Search results for "type"

Pathophysiology of Campylobacter jejuni infections of humans.

2000

Campylobacter jejuni and closely related organisms are major causes of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.

Lectotypification of the name Cistus stipulatus, basyonim of Helianthemum stipulatum (Cistaceae)

2015

The typification of the name Cistus stipulatus Forsskål (≡ Helianthemum stipulatum (Forsskål) Christensen) is discussed. The designation of the nomenclatural type is based on an assessment of Forsskål’s original material. The name is lectotypified selecting a specimen from the Herbarium Forsskålii in the National Herbarium Copenhagen at C.

Lack of association betweenMDM2promoter SNP309 and clinical outcome in patients with neuroblastoma

2014

While a polymorphism located within the promoter region of the MDM2 proto-oncogene, SNP309 (T > G), has previously been associated with increased risk and aggressiveness of neuroblastoma and other tumor entities, a protective effect has also been reported in certain other cancers. In this study, we evaluated the association of MDM2 SNP309 with outcome in 496 patients with neuroblastoma and its effect on MDM2 expression. No significant difference in overall or event-free survival was observed among patients with neuroblastoma with or without MDM2 SNP309. The presence of SNP309 does not affect MDM2 expression in neuroblastoma. Pediatr Blood Cancer 2014; 61:1867–1870. © 2014 Wiley Periodicals,…

Neurotrophic effects of central nicotinic receptor activation

2000

A growing number of data have shown that compounds interacting with neuronal nicotinic acetylcholine receptors (nAChRs) have, both in vivo and in vitro, the potential to be neuroprotective and that treatment with nAChR agonists elicit long-lasting improvement of cognitive performance in a variety of behavioural tests in rats, monkeys and humans. Epidemiological and clinical studies suggested also a potential neuroprotective/trophic role of (-)-nicotine in neurodegenerative disease, such as Alzheimer's disease and Parkinson's disease. This neuroprotective/trophic role of nAChR activation has been mainly mediated by alpha7 and alpha4beta2 nAChR subtypes, as evidenced using selective nAChR ant…

Fine-grain beta diversity in Palaearctic open vegetation: variability within and between biomes and vegetation types

2021

Aims: To quantify how fine-grain (within-plot) beta diversity differs among biomes and vegetation types. Study area: Palaearctic biogeographic realm. Methods: We extracted 4,654 nested-plot series with at least four different grain sizes between 0.0001 m² and 1,024 m² from the GrassPlot database spanning broad geographic and ecological gradients. Next, we calculated the slope parameter (z-value) of the power-law species–area relationship (SAR) to use as a measure of multiplicative beta diversity. We did this separately for vascular plants, bryophytes and lichens and for the three groups combined (complete vegetation). We then tested whether z-values differed between biomes, ecological-physi…

Harmonic balance analysis of pull-in range and oscillatory behavior of third-order type 2 analog PLLs

2020

The most important design parameters of each phase-locked loop (PLL) are the local and global stability properties, and the pull-in range. To extend the pull-in range, engineers often use type 2 PLLs. However, the engineering design relies on approximations which prevent a full exploitation of the benefits of type 2 PLLs. Using an exact mathematical model and relying on a rigorous mathematical thinking this problem is revisited here and the stability and pull-in properties of the third-order type 2 analog PLLs are determined. Both the local and global stability conditions are derived. As a new idea, the harmonic balance method is used to derive the global stability conditions. That approach…

LIMITS OF TRANSURETHRAL RESECTION IN DETECTING UNCOMMON HISTOLOGICAL VARIANTS WITHIN BULKY BLADDER TUMORS IN REAL-LIFE CLINICAL PRACTICE

2017

Trunk and lower limb muscle activation in linear, circular and spin back kicks

2015

Background and Study Aim: As any martial art, taekwondo can be classified as a specialty that requires high technical skills, such as a fine motor control both in static and dynamic conditions. Practitioners predominantly use kicks with high amplitude in both combat and technique (poomse) modalities. The aim of this study was the knowledge about trunk and lower limb muscle activation according to the type of kick (circular, linear and spin back kick) in the taekwondo technique modality. Material and Methods: Twelve healthy and elite male taekwondo athletes voluntarily participated in this study. Surface electromyography (EMG) during maximal isometric voluntary contractions (MVC) and executi…

Convergence Analysis of Distributed Set-Valued Information Systems

2016

This paper focuses on the convergence of information in distributed systems of agents communicating over a network. The information on which the convergence is sought is not rep- resented by real numbers, as often in the literature, rather by sets. The dynamics of the evolution of information across the net- work is accordingly described by set-valued iterative maps. While the study of convergence of set-valued iterative maps is highly complex in general, this paper focuses on Boolean maps, which are comprised of arbitrary combinations of unions, intersections, and complements of sets. For these important class of systems, we provide tools to study both global and local convergence. A distr…

Cytotoxicity of the Urokinase-Plasminogen Activator Inhibitor Carbamimidothioic Acid (4-Boronophenyl) Methyl Ester Hydrobromide (BC-11) on Triple-Neg…

2015

BC-11 is an easily synthesized simple thiouronium-substituted phenylboronic acid, which has been shown to be cytotoxic on triple negative MDA-MB231 breast cancer cells by inducing a perturbation of cell cycle when administered at a concentration equal to its ED50 at 72 h (117 μM). Exposure of cells to BC-11, either pre-absorbed with a soluble preparation of the N-terminal fragment of urokinase-plasminogen activator (uPa), or in co-treatment with two different EGFR inhibitors, indicated that: (i) BC-11 acts via binding to the N-terminus of the enzyme where uPa- and EGF receptor-recognizing sites are present, thereby abrogating the growth-sustaining effect resulting from receptor binding