Search results for "uci"

Alcoholic beverages, obesity, physical activity and other nutritional factors, and cancer risk: A review of the evidence

2016

International audience; Purpose: Prevention is a priority in the fight against cancers, especially nutritional prevention. To update the levels of evidence of relationships between 10 nutritional factors and cancer risk, the scientific literature published from 2006 to 2014 was reviewed by an expert group.Methods: Data from 133 meta-analyses, pooled analyses or intervention trials were examined. Nearly 150 relationships between nutritional factors and cancer at various sites were evaluated.Results: According to the evidence graded as convincing or probable, these factors were divided in two groups. Factors which increase the risk of cancer are alcoholic beverages, overweight and obesity, re…

Xenohormones and oral homeostasis : impact on taste preferences and salivary glands

2012

Oral homeostasis strongly influences taste perceptions. It depends on a healthy oral epithelium and salivary gland secretions, which are both regulated by sex hormones. The aim of this thesis was to identify the effect of an oral exposure to Bisphenol A, a food packaging and dental sealer component, and of a soy-diet containing phytoestrogens on oral homeostasisTwo experiments were conducted in adult rats: a dose-response study of BPA (5μg 12.5 mg / kj / day), and a study about the impact of a soy-diet on the BPA disrupting effects. By using gustation choice tests, and histological and qPCR-TR molecular approach, we identify for the first time an action of BPA on dry mouth. We found that BP…

Effect of incorporation of Brassica napus L. residues in soils on mycorrhizal fungus colonisation of roots and phosphorus uptake by maize (Zea mays L…

2007

International audience; Plants in the Brassicaceae family are known to contain thioglucoside compounds that produce isothiocyanates when tissues are disrupted. These chemicals have a negative effect on soil-borne fungal pathogens, and possibly on vesicular-arbuscular mycorrhizal (AM) fungi. We investigated the effect of incorporation of Brassica napus L. residues in a soil on mycorrhizal colonisation of roots, P uptake and growth of following maize (Zea mays L.) crop. A pot experiment was carried out in a glasshouse with pre-inoculation with Glomus intraradices (+I and -I), incorporation of B. napus L. residues (+R and -R) and mineral P fertilization (+P and -P) as studied factors. The soil…

Impact du système endocannabinoïdien sur la physiologie de l'obésité : effets de l'antagonisme des récepteurs CB1 sur le métabolisme glucido-lipidiqu…

2010

The endocannabinoïd system (ECS) is involved in many biological functions such as regulation of energy metabolism. Recently, several studies have shown an association between obesity and ECS overactivity. In addition, specific CB1R antagonists such as Rimonabant (SR141716) improved metabolic parameters in obese patients essentially through inactivation of central CB1R. However, peripheral CB1R inactivation could also contribute to the improvement of these parameters and it is this notion that we have studied. To this purpose, we tested the effects of SR141716 on obese mice in order to establish relationships between the ECS activity and lipid metabolism by looking more specifically to its r…

The σ B -dependent regulatory sRNA Rli47 represses isoleucine biosynthesis in Listeria monocytogenes through a direct interaction with the ilvA trans…

2019

International audience; The facultative intracellular pathogen Listeria monocytogenes can persist and grow in a diverse range of environmental conditions, both outside and within its mammalian host. The alternative sigma factor Sigma B (sigma(B)) plays an important role in this adaptability and is critical for the transition into the host. While some of the functions of the sigma(B) regulon in facilitating this transition are understood the role of sigma(B)-dependent small regulatory RNAs (sRNAs) remain poorly characterized. In this study, we focused on elucidating the function of Rli47, a sigma(B)-dependent sRNA that is highly induced in the intestine and in macrophages. Using a combinatio…

Identification and diagnosis of patients with familial chylomicronaemia syndrome (FCS): Expert panel recommendations and proposal of an "FCS score".

2018

Familial chylomicronaemia syndrome (FCS) is a rare, inherited disorder characterised by impaired clearance of triglyceride (TG)-rich lipoproteins from plasma, leading to severe hypertriglyceridaemia (HTG) and a markedly increased risk of acute pancreatitis. It is due to the lack of lipoprotein lipase (LPL) function, resulting from recessive loss of function mutations in the genes coding LPL or its modulators. A large overlap in the phenotype between FCS and multifactorial chylomicronaemia syndrome (MCS) contributes to the inconsistency in how patients are diagnosed and managed worldwide, whereas the incidence of acute hypertriglyceridaemic pancreatitis is more frequent in FCS. A panel of Eu…

"La faucille après le marteau"

2012

Arrêt des procédures d'exécution. Distribution du prix d'adjudication d'un immeuble

2020

International audience; (Com. 17 avr. 2019, n° 17-15.960, arrêt n° 338 F-P+B, Sté Caisse d'épargne CEPAC c/ Me V. De Carrière ès qual. et a., D. 2019. 1479, note A. Touzain ; Gaz. Pal. 15 oct. 2019, p. 43, note M. Guastella)

''La faucille après le marteau'' : le communisme aux champs dans l'entre-deux-guerres

2006

Las desigualdades de renta en la sociedad andaluza

1989

International audience