Search results for "urea"
showing 10 items of 888 documents
Helicobacter pylori infection does not affect the early rebleeding rate in patients with peptic ulcer bleeding after successful endoscopic hemostasis…
2003
Background and study aims Eradication of Helicobacter pylori infection can reduce the rebleeding rate of peptic ulcer bleeding in the long term. There are few data on the influence of H. pylori on the rebleeding rate in the acute phase of bleeding however. We therefore prospectively investigated the influence of H. pylori infection on the early rebleeding rate in patients who had undergone successful endoscopic hemostasis treatment for peptic ulcer bleeding. Patients and methods Between January 1996 and November 2000 all patients with peptic ulcer bleeding were evaluated consecutively. The diagnosis of H. pylori infection was made at index endoscopy, using histology and the rapid urease tes…
Pioglitazone in addition to metformin improves erythrocyte deformability in patients with Type 2 diabetes mellitus
2010
The aim of the present study was to compare the effect of PIO (pioglitazone) or GLIM (glimepiride) on erythrocyte deformability in T2DM (Type 2 diabetes mellitus). The study covered 23 metformin-treated T2DM patients with an HbA1c (glycated haemoglobin) >6.5%. Patients were randomized to receive either PIO (15 mg, twice a day) or GLIM (1 mg, twice a day) in combination with metformin (850 mg, twice a day) for 6 months. Blood samples were taken for the measurement of fasting glucose, HbA1c, fasting insulin, intact proinsulin, adiponectin and Hct (haematocrit). In addition, the erythrocyte EI (elongation index) was measured using laser diffractoscopy. Both treatments significantly impr…
Treatment with essential amino acids in patients on chronic hemodialysis: a double blind cross-over study.
1978
Patients on chronic hemodialysis may suffer from a latent protein deficiency, and therapy with essential amino acids has been recommended. In a double blind cross-over study, 13 hemodialysis patients received orally 15.7 g of essential amino acids daily over a 3-month period. Patients were on a liberal diet, containing 1 g of protein per kilogram of body weight per day. Hemodialysis was adequate. Therapy resulted in an increase in urea, uric acid, C3 c complement factor and a fall in C4. Lysine levels increased and phenylalanine fell. Malnutrition could not account for the observed metabolic changes, which are more likely due to uremic metabolic disturbances. A liberal diet of 1 g of protei…
Being an ethnic minority nursing student - A meta synthesis.
2022
Background Our society is characterized by a general globalization and has become more culturally diverse. This diversity is mirrored in nursing education. Purpose The purpose of the meta-synthesis is to identify and synthesize data from primary, qualitative studies of ethnic minority nursing students' experiences in a nursing program. Method Electronic databases, Medline, Embase, and CINAHL, were searched for studies published in English or Nordic languages from 1980 to February 2020. Results The search generated 1070 unique citations, of which 19 articles met the inclusion criteria. The included studies had a total sample size of 255 students, age range 19–50 years. The participants origi…
A case of severe dermatitis in a patient with Polycythemia Vera during cytoreductive therapy
2019
Polycythemia Vera (PV) is a Philadelphia-negative chronic myeloproliferative neoplasm (MPN) mainly characterized by erythrocytosis. In this report we describe a case of severe cutaneous toxicity in patients with PV treated with hydroxyurea. A 72-year-old woman diagnosed with PV with V617F mutation of JAK2 performed more than 10 years before and treated with hydroxyurea plus phlebotomies and low-dose ASA for about 7 years addressed our center for the appearance of serious dermatitis at the face symptomatic for severe itch. The patient underwent a dermatology visit with diagnosis of desquamative dermatitis due to iatrogenic cause related to the use of hydroxyurea. HU was stopped for a month w…
Urea Cycle Metabolites and Atrial Fibrillation or Heart Failure Risk: Two Case-Control Studies in the PREDIMED Trial
2021
OBJECTIVES: To prospectively analyze the associations between urea cycle metabolites and incident atrial fibrillation (AF) or heart failure (HF), and to evaluate the effect of a Mediterranean diet (MD) intervention on such associations. METHODS: We designed two nested case-control studies within the PREDIMED trial, a randomized controlled trial aimed to evaluate the effect of two MD interventions, supplemented with either extra virgin olive oil (EVOO) or nuts, on cardiovascular disease (CVD). Fasting blood samples were collected at baseline and urea cycle metabolites (arginine, citrulline, and ornithine) and methylarginines (asymmetric dimethylarginine/symmetric dimethylarginine ratio (ADMA…
Manejo de la hiperglucemia con fármacos no insulínicos en pacientes adultos con diabetes tipo 2
2019
Resumen: El adecuado tratamiento de la diabetes mellitus tipo 2 (DM2) incluye la alimentación saludable y el ejercicio (150 min/semana) como pilares básicos. Para el tratamiento farmacológico, la metformina es el fármaco de elección inicial, salvo contraindicación o intolerancia; en caso de mal control, se dispone de 8 familias terapéuticas (6 orales y 2 inyectables) como posibles combinaciones. Se presenta un algoritmo y unas recomendaciones para el tratamiento de la DM2. En prevención secundaria cardiovascular se recomienda asociar un inhibidor del cotransportador sodio-glucosa tipo 2 (iSGLT2) o un agonista del receptor de glucagon-like peptide-1 (arGLP1) en pacientes con obesidad. En pre…
Le fortificazioni di Akragas: il settore presso la cosiddetta Porta Aurea
2020
L’identificazione della porta ad mare ferens, ricordata da Livio per le vicende della conquista romana di Agrigento nel 211/0 a.C., ha costituito uno degli argomenti di maggior interesse per gli studiosi della topografia della città, in connessione con la localizzazione dell’agorà-foro e del non lontano tempio di Eracle/Ercole. Nel quindicennio scorso ha prevalso l’ipotesi, avanzata da G. Tripodi nel 2003, che la porta principale di collegamento con la costa sia da ubicare a Est (attuale giardino di Villa Aurea) e non già ad Ovest (sito della cosiddetta Porta Aurea) del Tempio A/ cosiddetto Tempio di Eracle; da ultimo, V. Caminneci e G. Cucchiara hanno invece rivalutato l’importanza anche d…
Centaurea aspera subsp. geladensis, subsp. nov. (sect. seridia (Juss.) DC., Asteraceae), un nuevo taxon para la flora valenciana
2018
Se describe una nueva subespecie de Centaurea aspera L. (sect. Seridia (Juss.) DC., Asteraceae) procedente de las dunas fósiles del Parque Natural de Serra Gelada (L’Alfàs del Pi y Benidorm, Alicante, España). Se proporcionan datos morfológicos y ecológicos que permiten la diferenciación de la nueva subespecie con sus dos parientes cercanos C. aspera subsp. aspera y C. aspera subsp. stenophylla. A new subspecies of Centaurea aspera L. (sect. Seridia (Juss.) DC., Asteraceae) is described from the fossil dunes of Serra Gelada Natural Park (L’Alfàs del Pi and Benidorm, Alicante, Spain). Morphological and ecological data are provided which allow differentiation from the close relatives C. asper…
Üher den Ureidstoffwechsel heim Lauhmoosprotonema von Funaria hygrometrica L. (SIBTH.)
1974
Summary The uptake of allantoine-7- 14 C by moss protonema grown in submerged culture is controlled by light and by the degree of catabolisation within the cell. The rate of uptake was enhanced by the application of ATP + glucose to the medium of a dark grown culture. The degradation products of allantoine-7- 14 C in light grown protonema are allantoic acid and urea. Urea is degraded in the Henseleit-Krebs-cycle to ornithine, citrulline and arginine. Urea is a further source of radioactive CO 2 . In darkness, the single product of allantoine degradation is allantoic acid. Allantoicase is blocked in the dark but the metabolism can be activated by the application of ATP or ATP + glucose to th…