Search results for "usage"

Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria

2005

International audience; Most endosymbiotic bacteria have extremely reduced genomes, accelerated evolutionary rates, and strong AT base compositional bias thought to reflect reduced efficacy of selection and increased mutational pressure. Here, we present a comparative study of evolutionary forces shaping five fully sequenced bacterial endosymbionts of insects. The results of this study were three-fold: (i) Stronger conservation of high expression genes at not just nonsynonymous, but also synonymous, sites. (ii) Variation in amino acid usage strongly correlates with GC content and expression level of genes. This pattern is largely explained by greater conservation of high expression genes, l…

A manipulative parasite increasing an antipredator response decreases its vulnerability to a nonhost predator.

2009

8 pages; International audience; Trophically transmitted parasites have to deal with the antipredator adaptations of their intermediate hosts. Some of these parasites induce behavioural changes in their intermediate hosts that make them more vulnerable to predation by definitive hosts. However, the adaptiveness of behavioural manipulation also depends on the probability of being eaten by a nonhost predator. Parasites might therefore try to use specific antipredator responses of intermediate hosts to avoid this dead end. We tested this hypothesis using the acanthocephalan Polymorphus minutus and its intermediate amphipod host, Gammarus roeseli. In their natural habitat, uninfected G. roeseli…

Evolutionary Changes after Translational Challenges Imposed by Horizontal Gene Transfer

2019

International audience; Genes acquired by horizontal gene transfer (HGT) may provide the recipient organism with potentially new functions, but proper expression level and integration of the transferred genes in the novel environment are not granted. Notably, transferred genes can differ from the receiving genome in codon usage preferences, leading to impaired translation and reduced functionality. Here, we characterize the genomic and proteomic changes undergone during experimental evolution of Escherichia coli after HGT of three synonymous versions, presenting very different codon usage preference, of an antibiotic resistance gene. The experimental evolution was conducted with and without…

2018

Amino acid usage in a proteome depends mostly on its taxonomy, as it does the codon usage in transcriptomes. Here, we explore the level of variation in the codon usage of a specific amino acid, glutamine, in relation to the number of consecutive glutamine residues. We show that CAG triplets are consistently more abundant in short glutamine homorepeats (polyQ, four to eight residues) than in shorter glutamine stretches (one to three residues), leading to the evolutionary growth of the repeat region in a CAG-dependent manner. The length of orthologous polyQ regions is mostly stable in primates, particularly the short ones. Interestingly, given a short polyQ the CAG usage is higher in unstable…

Study of the polysemic term of minerality in wine: Segmentation of consumers based on their textual responses to an open-ended survey

2016

International audience; Over the past 20 years, the word "minerality" has been increasingly used in the description of wines. However, a precise definition of the concept of minerality appears to be inexistent, and no consensual meaning, even among wine professionals, can be identified. Although this word usage seems to spread out from wine professionals to consumers, research on what consumers assume about minerality is scarce. This paper aims to study the various concepts about minerality held-by consumers by using an open-ended questionnaire.A total of 1697 French-speaking consumers responded to an, online survey and their free answers were analysed using statistical textual methods. The…

Predicting response to transdiagnostic iCBT for emotional disorders from patient and therapist involvement

2021

Background Transdiagnostic iCBT has been shown to be effective for the treatment of emotional disorders. Less is known about the optimal level of therapist and patient involvement in these interventions. Specific characteristics of Internet-delivered interventions include treatment adherence (e.g., amount of review of the materials) and guidance (e.g., amount of therapist support). Exploring the importance of these elements in treatment outcome may help to maximize the efficiency of Internet-delivered psychological interventions. Aim In this study, we aimed to analyze the relationship between patient and therapist involvement (i.e., platform usage and amount of therapist guidance) in a samp…

Between ideologies and realities: Multilingual competence in a languagised world

2016

AbstractRecent developments in sociolinguistics and applied linguistics have put emphasis on the contrast between ideologies of distinct ‘languages’ and the multifaceted reality of linguistic practices. This article argues that recent usage-based reconceptualisations of the notions of competence and repertoire can help paint a more complex picture of the relationship between monolingual ‘ideologies’ and diverse linguistic ‘realities’. Drawing on data from interviews with highly proficient adult speakers of Finnish as a second language, I explore some aspects of how speakers’ competence can be understood as shaped by language use, and what role linguistic ideologies, social expectations and …

Sharenting and the exercise of parental authority: the first court decisions

2020

El sharenting, fenómeno social ampliamente extendido que consiste en que los progenitores publican fotografías y vídeos de sus hijos menores de edad en sus redes sociales, plantea el problema de si es suficiente el consentimiento del progenitor usuario de la red social o es necesario el de ambos progenitores. Acerca de esta cuestión se han pronunciado varias Audiencias Provinciales, cuyas sentencias se analizan en el presente trabajo. Las mismas se refieren, en primer lugar, a la cuestión de en qué medida el sharenting afecta al derecho a la propia imagen y al de protección de datos personales de los menores y cuándo es necesario el consentimiento de los progenitores para la disposición de …

E-book on the library shelf: access and usage in the researchprocess

2014

Presentation from the workshop "Informational services for research process" (14.-16.04.2014., Riga).

Digital resources in senegalese hight education : state of play and prospective study

2014

It is in the context of poverty or information exclusion that the massive dissemination of information and technology tools in Senegalese academic libraries responds to an urgent need for transformation and improvement of operational modes as well as modernization of services for different audiences, in particular students. Currently, in almost all academic and research libraries of Senegal digitization activities that crossed the rise of the Internet are being developed. This has created a real increasing effect of digital resources, by the establishment of means of creation and by expansion of access and of sharing of scientific and technical information in higher education institutions. …