Search results for "value"

showing 10 items of 5321 documents

Muscle cross-sectional area and voluntary force production characteristics in elite strength- and endurance-trained athletes and sprinters

1989

Seven male elite strength-trained athletes (SA) from different weight categories, six elite sprinters (SPA) and seven elite endurance-trained athletes (EA) volunteered as subjects for examination of their muscle cross-sectional area (CSA), maximal voluntary isometric force, force-time and relaxation-time characteristics of the leg extensor muscles. The SA group demonstrated slightly greater CSA and maximal absolute strength than the SPA group, while the EA group demonstrated the smallest values both in CSA and especially in maximal strength (p<0.05). When the maximal forces were related to CSA of the muscles, the mean value for the SA group of 60.8±10.0 N·cm−2 remained slightly greater than…

AdultMaleMuscle tissuemedicine.medical_specialtyPhysiologyIsometric exerciseIsometric ContractionPhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineExercise physiologyExercisebiologybusiness.industryAthletesMusclesMean valuePublic Health Environmental and Occupational HealthGeneral Medicinebiology.organism_classificationCross section (geometry)medicine.anatomical_structureEndocrinologySprintTurnoverPhysical EndurancePhysical therapybusinessEuropean Journal of Applied Physiology and Occupational Physiology
researchProduct

The Use of Acoustic Rhinometry in Predicting Outcomes after Sinonasal Surgery

2000

Today's healthcare environment demands objective assessment of surgical outcomes. The recent otolaryngologic literature has established acoustic rhinometry (AR) as a valid instrument to objectively document nasal patency. The purpose of this article is to evaluate the utility of AR in predicting outcomes after sinonasal surgery. All patients scheduled for sinonasal surgery at the Tulane University and University of Mainz Departments of Otolaryngology between 10/1/98 and 12/15/98 were enrolled. All subjects underwent AR and completed a sinonasal outcome survey (SNOT-20) one day before and two months after their surgical procedure. Thirty-one patients were enrolled. The SNOT-20 raw scores im…

AdultMaleNasal cavitymedicine.medical_specialtyManometryObjective assessment03 medical and health sciencesSubjective improvement0302 clinical medicineAcoustic rhinometryPredictive Value of TestsParanasal SinusesmedicineHumansRaw score030223 otorhinolaryngologybusiness.industryMean valueSurgeryTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyOtorhinolaryngology030220 oncology & carcinogenesisFemalebusinessAmerican Journal of Rhinology
researchProduct

Spatial variability of muscle activity during human walking: The effects of different EMG normalization approaches

2015

Human leg muscles are often activated inhomogeneously, e.g. in standing. This may also occur in complex tasks like walking. Thus, bipolar surface electromyography (sEMG) may not accurately represent whole muscle activity. This study used 64-electrode high-density sEMG (HD-sEMG) to examine spatial variability of lateral gastrocnemius (LG) muscle activity during the stance phase of walking, maximal voluntary contractions (MVCs) and maximal M-waves, and determined the effects of different normalization approaches on spatial and inter-participant variability. Plantar flexion MVC, maximal electrically elicited M-waves and walking at self-selected speed were recorded in eight healthy males aged 2…

AdultMaleNormalization (statistics)EMG normalizationmedicine.medical_specialtyWalkingElectromyographyta3112Young AdultPhysical medicine and rehabilitationmedicineHumansHuman legMuscle activityMultichannel EMGMuscle Skeletalta315MathematicsLegmedicine.diagnostic_testElectromyographyGeneral NeuroscienceReproducibility of ResultsSignal Processing Computer-AssistedElectric StimulationElectromyogramData Interpretation StatisticalGait analysisPhysical therapySpatial variabilityGait analysisPeak valuehuman activitiesLateral gastrocnemiusNEUROSCIENCE
researchProduct

Topical Antibiotic, Antifungal, and Antiseptic Solutions Decrease Ciliary Activity in Nasal Respiratory Cells

2002

This study was designed to investigate whether topical solutions, as they are used in the treatment of selected cases of rhinosinusitis, influence nasal mucociliary clearance. The objective of this study was to evaluate the effects of the following topical solutions on the ciliary beat frequency (CBF) of nasal respiratory cells: ofloxacin as an antibiotic; Betadine and hydrogen peroxide (H2O2) as antiseptic; and amphotericin B, itraconazole, and clotrimazole as antifungal solutions. Differences are described between effects of each of these substances and we clarify whether ciliotoxic effects are dose dependent and if they can be reduced or eliminated by diluting the concentration of the a…

AdultMaleOfloxacinAntifungal AgentsMucociliary clearanceItraconazolemedicine.drug_classAntibioticsPharmacologySensitivity and SpecificityMicrobiology03 medical and health sciences0302 clinical medicineAntisepticReference ValuesAmphotericin BAmphotericin BmedicineHumansClotrimazoleRespiratory system030223 otorhinolaryngologyPovidone-IodineCells CulturedDose-Response Relationship Drugbusiness.industryClotrimazoleNasal MucosaOtorhinolaryngologyMucociliary Clearance030220 oncology & carcinogenesisAnti-Infective Agents LocalFemaleOfloxacinItraconazolebusinessmedicine.drugAmerican Journal of Rhinology
researchProduct

The clinical value of tumor burden at diagnosis in Hodgkin lymphoma

2004

BACKGROUND The authors investigated the clinical role of tumor burden (TB) in patients with Hodgkin lymphoma, relating this parameter to most of the current clinical and prognostic factors and to the best predictive multifactorial models. METHODS The volume of TB at diagnosis was measured directly from the initial staging computed tomography scans in 351 patients who were treated on standard protocols. The mean patient age was 34.0 years ± 16.4 years. Forty-six patients had clinical Stage I disease, 201 patients had Stage II disease, 64 patients had Stage III disease, and 40 patients had Stage IV disease. There were 146 symptomatic patients. Overall survival (OS), disease-free survival (DFS…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyTime FactorsMultivariate analysisAdolescentBody Surface AreaDiseaseLogistic regressionText miningPredictive Value of TestsInternal medicineBiomarkers TumormedicineHumansTreatment FailureStage (cooking)Neoplasm StagingRetrospective StudiesBody surface areabusiness.industryRemission InductionCancerMiddle AgedPrognosismedicine.diseaseHodgkin DiseaseSurgeryLymphomaSurvival RateOncologyFemaleTomography X-Ray ComputedbusinessCancer
researchProduct

Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease

2014

Chronic obstructive pulmonary disease (COPD) and lung cancer are widespread lung diseases. Cigarette smoking is a high risk factor for both the diseases. COPD may increase the risk of developing lung cancer. Thus, it is crucial to be able to distinguish between these two pathological states, especially considering the early stages of lung cancer. Novel diagnostic and monitoring tools are required to properly determine lung cancer progression because this information directly impacts the type of the treatment prescribed. In this study, serum samples collected from 22 COPD and 77 lung cancer (TNM stages I, II, III, and IV) patients were analyzed. Then, a collection of NMR metabolic fingerprin…

AdultMaleOncologymedicine.medical_specialtyLung NeoplasmsMagnetic Resonance SpectroscopyClinical BiochemistryPharmaceutical ScienceCreatineAnalytical ChemistryDiagnosis DifferentialPulmonary Disease Chronic Obstructivechemistry.chemical_compoundPredictive Value of TestsCarcinoma Non-Small-Cell LungInternal medicineDrug DiscoveryBiomarkers TumormedicineHumansMetabolomicsLeast-Squares AnalysisRisk factorLung cancerLungPathologicalEarly Detection of CancerSpectroscopyAgedNeoplasm StagingAged 80 and overUnivariate analysisCOPDLungChemistryDiscriminant AnalysisMiddle AgedPrognosismedicine.diseaserespiratory tract diseasesmedicine.anatomical_structureMultivariate AnalysisDisease ProgressionFemaleLung cancer stagingJournal of Pharmaceutical and Biomedical Analysis
researchProduct

PML expression in soft tissue sarcoma: Prognostic and predictive value in alkylating agents/antracycline-based first line therapy

2012

Soft tissue sarcomas are aggressive tumors representing <1% of all adult neoplasms. Aim of our study was to evaluate promyelocytic leukemia gene expression value as prognostic factor and as a factor predicting response to alkylating agents/antracycline-based first line therapy. One hundred eleven patients affected by locally advanced and metastatic soft tissue sarcoma were selected. PML expression was evaluated by immunohistochemical analysis in pathological samples and in the corresponding normal tissue from each case. PML immunohistochemical results were correlated with prognosis and with radiological response to alkylating agents/antracycline-based first line therapy. PML expression was …

AdultMaleOncologymedicine.medical_specialtySettore MED/06 - Oncologia MedicaPhysiologyClinical BiochemistryCellDown-RegulationSoft Tissue NeoplasmsPromyelocytic Leukemia ProteinLiposarcomaPleomorphic LiposarcomaYoung AdultPredictive Value of TestsInternal medicinemedicineHumansAnthracyclinesAntineoplastic Agents AlkylatingPathologicalAgedRetrospective StudiesAged 80 and overPMLbusiness.industryTumor Suppressor ProteinsSoft tissue sarcomaNuclear ProteinsSoft tissueSarcomaCell BiologyMiddle AgedPrognosismedicine.diseaseImmunohistochemistrymedicine.anatomical_structuresoft tissue sarcomas; PMLDrug Resistance Neoplasmsoft tissue sarcomaImmunologyImmunohistochemistryFemaleSarcomabusinessTranscription Factors
researchProduct

Insight in schizophrenia–course and predictors during the acute treatment phase of patients suffering from a schizophrenia spectrum disorder

2012

AbstractBackgroundTo analyse insight of illness during the course of inpatient treatment, and to identify influencing factors and predictors of insight.MethodsInsight into illness was examined in 399 patients using the item G12 of the Positive and Negative Syndrome Scale (“lack of insight and judgement”). Ratings of the PANSS, HAMD, UKU, GAF, SOFAS, SWN-K and Kemp's compliance scale were performed and examined regarding their potential association with insight. The item G12 was kept as an ordinal variable to compare insight between subgroups of patients.ResultsAlmost 70% of patients had deficits in their insight into illness at admission. A significant improvement of impairments of insight …

AdultMaleOrdinal datamedicine.medical_specialtyMedizin03 medical and health sciences0302 clinical medicineTreatment targetsPredictive Value of TestsHamdmedicineHumansPsychiatryPsychiatric Status Rating ScalesPositive and Negative Syndrome ScaleAwarenessmedicine.disease030227 psychiatryPsychiatry and Mental healthInsight into illnessSchizophreniaAcute DiseaseSchizophreniaFemaleSchizophrenic PsychologyPsychology030217 neurology & neurosurgeryClinical psychologySchizophrenia spectrumEuropean Psychiatry
researchProduct

An experimental study of the esthetic effect of facial profiles

1998

In this study good-looking "male" and "female" as well as ugly facial profiles were shaped by 104 lay persons using an especially constructed device according to specific instructions. These profiles were photographed and subsequently evaluated using a series of parameters from soft tissue profile analyses. Although some significant mean value differences were found between the good-looking and ugly profile variants, they were not substantial. In contrast, markedly significant differences were revealed between the variances of all variables. In some instances the variance of the ugly profiles was more than 3 to 4 times higher than that of the good-looking profiles. These findings were convi…

AdultMaleOrthodonticsAdolescentCephalometryFacial profileMean valueContrast (statistics)OrthodonticsEsthetics DentalMiddle AgedConvexityBeautyFacePhotographyHumansFemaleOral SurgeryAgedMathematicsJournal of Orofacial Orthopedics / Fortschritte der Kieferorthop�die
researchProduct

Pain-evoked blink reflex

1997

The electrically evoked blink reflex (BR) consists of an ipsilateral R1 component (R1) at 11 ms and two bilateral components R2 at 33 ms and R3 at 83 ms. It is still unclear whether the R2 is mediated by activation of tactile or nociceptive afferents. For testing the nociceptive hypothesis, nociceptors of the supraorbital nerve were selectively activated by infrared laser stimuli in 10 subjects. Only painful laser stimuli evoked a bilateral early polyphasic BR response (LR2) at 71 ms. Stimulation of infraorbital and mental nerve dermatomes was equally effective. A late bilateral reflex response at 130 ms was occasionally observed. Regarding the nociceptor activation time of about 40 ms, ons…

AdultMalePain ThresholdChinHot TemperatureInfrared RaysPhysiologyPainStimulationReflex responseCellular and Molecular NeuroscienceReference ValuesPhysiology (medical)Reaction TimeHumansMedicineNervous System Physiological PhenomenaCorneal reflexSkinBlinkingbusiness.industryLasersNociceptorsSupraorbital nerveMental nerveElectric StimulationLipNociceptionNociceptorFemaleNeurology (clinical)businessOrbitNeuroscienceMuscle &amp; Nerve
researchProduct