Search results for "value"

PS-039 DokuPIK – Pharmaceutical interventions: Do ward pharmacists know how to document?

2014

Background The internet-based categorical, hierarchical documentation system for routine pharmaceutical interventions (PIs) DokuPIK is widely used especially among German ward-based pharmacists. Purpose To conduct a survey-based study on its clinical usability. Materials and methods Out of 498 registered DokuPIK users, 37 volunteered to independently evaluate 24 standardised case reports 1 between 01–03 2012. Case evaluation was restricted to the reason for PI and was performed based on 26 given survey items with no limit on the number of items chosen. Ratings were conducted electronically and anonymously. In order to define meaningful reference item selections, majority decisions made by 5…

Evidence-based medicine and the problem of healthy volunteers

2017

Abstract Healthy controls are subjects without the disease being studied but may have other conditions indirectly affecting outcome. In the present epidemics of obesity a few subjects with undiagnosed nonalcoholic fatty liver disease enter clinical studies as controls, producing biased results. Stricter selection criteria should be considered to prevent this risk.

268Prognostic value of dipyridamole stress CMR in patients with known or suspected coronary artery disease: a long term follow-up study

2019

Magnetic Resonance Assessment of Left Ventricular Ejection Fraction at Any Time Post-Infarction for Prediction of Subsequent Events in a Large Multic…

2021

Background Magnetic resonance imaging (MRI) is the most accurate imaging technique for left ventricular ejection fraction (LVEF) quantification, but as yet the prognostic value of LVEF assessment at any time after ST-segment elevation myocardial infarction (STEMI) for subsequent major adverse cardiac event (MACE) prediction is uncertain. Purpose To explore the prognostic impact of MRI-derived LVEF at any time post-STEMI to predict subsequent MACE (cardiovascular death or re-admission for acute heart failure). Study Type Prospective. Population One thousand thirteen STEMI patients were included in a multicenter registry. Field Strength/Sequence 1.5-T. Balanced steady-state free precession (c…

Long-term prognostic implications of revascularization in patients with known or suspected chronic coronary syndromes without ischemia in vasodilator…

2021

In this study, we evaluated the association between symptoms-guided revascularization occurred within three months following a negative vasodilator stress cardiovascular magnetic resonance (negative stress-CMR) and long-term adverse events in patients with known or suspected chronic coronary syndrome (CCS).We retrospectively evaluated 3517 patients in which the stress first-pass perfusion imaging revealed no ischemia. The primary endpoint was the composite of death, spontaneous myocardial infarction, heart failure (HF), or stroke. The association between symptoms-guided revascularization after a negative stress-CMR and the endpoint was assessed using the multivariable Cox proportional hazar…

Stress cardiac magnetic resonance for mortality prediction and decision-making: registry of 2496 elderly patients with chronic coronary syndrome

2022

Abstract Introduction and objectives The management of elderly patients with chronic coronary syndrome (CCS) is challenging. We explored the prognostic value and usefulness for decision-making of ischemic burden determined by vasodilator stress cardiac magnetic resonance (CMR) imaging in elderly patients with known or suspected CCS. Methods The study group comprised 2496 patients older than 70 years who underwent vasodilator stress CMR for known or suspected CCS. The ischemic burden (number of segments with stress-induced perfusion deficit) was calculated following the 17-segment model. Subsequently, we retrospectively analyzed its association with all-cause mortality and the effect of CMR-…

Undetected Malignancies of the Breast: Dynamic Contrast-enhanced MR Imaging at 1.0 T

2002

To assess the prevalence and characteristics of malignant breast lesions not identified with magnetic resonance (MR) imaging.Breast tissue specimens were obtained in 464 of 967 patients who had undergone dynamic gadolinium-enhanced T1-weighted fast low-angle shot three-dimensional MR imaging of both breasts. A comparison of sensitivity, specificity, and predictive values of the prospectively recorded findings of mammography, ultrasonography (US), and MR imaging with the histopathologic results was performed with receiver operating characteristic (ROC) curve analysis. MR imaging examination findings that caused a false-negative diagnosis were reviewed to identify possible sources of error.Hi…

Fair Value Accounting versus Historical Cost Accounting: a theoretical framework for judgment in financial crisis

2013

Since the 2008 global economical and financial crisis, the fair value measurement has acquired a controversial position both within the accounting regulatory committees and the accounting theory. The literature generally examines two opposite central paradigms of evaluation, namely the Fair Value Accounting (FVA) and the Historical Cost Accounting (HCA). The paper, after a literature review through both these opposite sides, suggests a theoretical framework, using the basic concept of “accounting system”, for the choice between the opposite paradigms, considered noteworthy in times of crisis as it should allow to conceptualize a ‘mixed system’, combining FVA and HCA in different ways accord…

Radiation transmission data for radionuclides and materials relevant to brachytherapy facility shielding

2008

To address the limited availability of radiation shielding data for brachytherapy as well as some disparity in existing data, Monte Carlo simulation was used to generate radiation transmission data for 60Co, 137CS, 198Au, 192Ir 169Yb, 170Tm, 131Cs, 125I, and 103pd photons through concrete, stainless steel, lead, as well as lead glass and baryte concrete. Results accounting for the oblique incidence of radiation to the barrier, spectral variation with barrier thickness, and broad beam conditions in a realistic geometry are compared to corresponding data in the literature in terms of the half value layer (HVL) and tenth value layer (TVL) indices. It is also shown that radiation shielding calc…

Broad-beam transmission data for new brachytherapy sources, Tm-170 and Yb-169

2005

The characteristics of the radionuclides (170)Tm and (169)Yb are highly interesting for their use as high dose-rate brachytherapy sources. The introduction of brachytherapy equipment containing these sources will lead to smaller required thicknesses of the materials used in radiation protection barriers compared with the use of conventional sources such as (192)Ir and (137)Cs. The purpose of this study is to determine the required thicknesses of protection material for the design of the protecting walls. Using the Monte Carlo method, transmission data were derived for broad-beam geometries through lead and concrete barriers, from which the first half value layer and tenth value layer are ob…