Search results for "valve"

showing 10 items of 576 documents

Exercise stress CMR reveals reduced aortic distensibility and impaired right-ventricular adaptation to exercise in patients with repaired tetralogy o…

2018

International audience; The aim of our study was to evaluate the feasibility of exercise cardiac magnetic resonance (CMR) in patients with repaired tetralogy of Fallot (RTOF) and to assess right and left ventricular adaptation and aortic wall response to exercise in comparison with volunteers.Methods11 RTOF and 11 volunteers underwent prospective CMR at rest and during exercise. A supine bicycle ergometer was employed to reach twice the resting heart rate during continuous exercise, blood pressure and heart rate were recorded. Bi-ventricular parameters and aortic stiffness were assessed using accelerated cine sequences and flow-encoding CMR. A t-test was used to compare values between group…

MalePhysical-ExerciseVentricular Dysfunction RightBlood PressureVascular MedicineVentricular Dysfunction Left[SPI]Engineering Sciences [physics]Heart RateMedicine and Health SciencesPublic and Occupational HealthProspective StudiesCardiac OutputMaterialsAortaTreadmillQRHeartRegurgitationMagnetic Resonance ImagingSports SciencePulmonary Valve-ReplacementPhysical SciencesTetralogy of FallotMagnetscardiovascular systemMedicineFemale[SDV.IB]Life Sciences [q-bio]/BioengineeringAnatomyResearch ArticleAdultCardiac VentriclesScienceHeart VentriclesRestMaterials ScienceCardiologyStress PhysiologicalAscending AortaHumansSports and Exercise MedicineExerciseCardiac MriHemodynamicsBiology and Life SciencesStroke VolumePhysical ActivityElasticityPhysical FitnessCongenital Heart-DiseaseExercise TestCardiovascular AnatomyRate-Pressure ProductFeasibility StudiesBlood VesselsArterial Stiffness
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Non-sutureless minimally invasive aortic valve replacement: mini-sternotomy versus mini-thoracotomy: a series of 1130 patients

2016

Objectives Aortic valve replacement through conventional sternotomy still represents the gold-standard surgical approach for aortic valve disease. However, given the increasing number of patients with comorbidities, strategies that can improve operative results are always sought. Minimally invasive aortic valve surgery, although related to a steep learning curve, might be associated with improved postoperative outcomes. The main aim of this study was to assess whether significant differences exist in terms of operative and early results between a mini-sternotomy and a right mini-thoracotomy approach for isolated aortic valve replacement without sutureless technologies. Methods This is an ob…

MalePulmonary and Respiratory MedicineAortic valveAortic valve replacement • Exposure • Incision • Minimally invasive surgery • Surgery • Techniquemedicine.medical_specialtymedicine.medical_treatmentHeart Valve Diseases030204 cardiovascular system & hematologylaw.invention03 medical and health sciences0302 clinical medicineAortic valve replacementlawmedicineCardiopulmonary bypassHumansMinimally Invasive Surgical ProceduresThoracotomyAgedRetrospective StudiesHeart Valve Prosthesis Implantationbusiness.industrySuture TechniquesAortic valve disorderRetrospective cohort studymedicine.diseaseSternotomySurgerymedicine.anatomical_structureThoracotomy030228 respiratory systemAortic ValveHeart Valve ProsthesisAortic valve surgeryFemaleSurgeryObservational studyCardiology and Cardiovascular Medicinebusiness
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Histological and genetic studies in patients with bicuspid aortic valve and ascending aorta complications.

2011

OBJECTIVES: Aneurysm diameter and growing rate does not represent a definite parameter for operation in bicuspid aortic valve (BAV), ascending aortic aneurysm and normal root patients. Thus, we investigated histological and immunohistochemical aspects of different segments of ascending aorta (precisely, aortic root without dilatation, aneurysmatic tubular portion, dissected ascending aorta) and genetic features of patients with BAV and ascending aorta complication (aneurysm or dissection). METHODS: Aorta tissue samples of 24 BAV patients were examined. The patients comprised of 18 men and 6 women; the mean age was 54.2 ± 14.3 years. All patients underwent composite aortic root replacement (…

MalePulmonary and Respiratory MedicineAortic valveGenotypeBicuspid aortic valveHeart Valve DiseasesAorta ThoracicApoptosisPolymerase Chain ReactionPolymorphism Single NucleotideAortic aneurysmAneurysmBicuspid aortic valveRisk Factorsmedicine.arteryAscending aortaIn Situ Nick-End LabelingmedicineHumansThoracic aortaSettore MED/05 - Patologia ClinicaGenetic Predisposition to DiseaseCystRetrospective StudiesAortaAortic Aneurysm Thoracicbusiness.industryDissectionSettore MED/23 - Chirurgia CardiacaFollow-up PapersDNAAnatomyMiddle Agedmedicine.diseaseImmunohistochemistryAneurysmEchocardiography Doppler ColorAortic Dissectionmedicine.anatomical_structureAortic Valvecardiovascular systemFemaleSurgeryCardiology and Cardiovascular MedicinebusinessBiomarkersEchocardiography TransesophagealFollow-Up Studies
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Relocation of Papillary Muscles for Ischemic Mitral Valve Regurgitation

2014

Objective The assessment of the mitral valve apparatus (MVA) and its modifications during ischemic mitral regurgitation (IMR) is better performed by three-dimensional (3D) transesophageal echocardiography (TEE). The aim of our study was to carry out nonrestrictive mitral annuloplasty in addition to relocation of papillary muscles (PPMs) oriented by preoperative real-time 3D TEE through the mitral valve quantification dedicated software. Methods Since January 2008, a total of 70 patients with severe IMR were examined both before and after mitral valve repair. The mean (SD) coaptation depth and the mean (SD) tenting area were 1.4 (0.4) cm and 3.2 (0.5) cm2, respectively. Intraoperative 3D TEE…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyMitral Valve AnnuloplastyMyocardial ischemiamedicine.medical_treatmentTreatment outcomeMyocardial IschemiaEchocardiography Three-DimensionalThree-dimensional echocardiographyPapillary MuscleIschemic mitral valve regurgitationIntraoperative PeriodRetrospective StudieInternal medicineMitral valveMitral valve annuloplastymedicineHumansRetrospective StudiesAgedMitral valve repairIschemic mitral regurgitationbusiness.industryMitral Valve InsufficiencyGeneral MedicinePapillary Musclesmedicine.diseaseFeasibility StudieTreatment Outcomemedicine.anatomical_structureCardiologyFeasibility StudiesFemaleSurgeryIntraoperative PeriodbusinessMitral valve regurgitationCardiology and Cardiovascular MedicineMitral valve repairEchocardiography TransesophagealHumanInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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Impact of moderate ischemic mitral regurgitation after isolated coronary artery bypass grafting

2009

The aim of the study was to evaluate the clinical and echocardiographic outcomes, at rest and under exercise testing, of patients with moderate ischemic mitral regurgitation (IMR) undergoing isolated coronary artery bypass graft surgery (CABG).Between February 2003 and March 2008, 180 patients with moderate IMR who had isolated CABG were enrolled. Patients were matched 1:2 (n = 360) with patients who underwent isolated CABG without IMR (by propensity score). The study endpoints were freedom from all death, cardiac related-death, late events, and cardiac-related events. Late outcomes and left ventricular remodeling were evaluated according to preoperative percent of ejection fraction. Sympto…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtycoronary artery byoass graftingRestmedicine.medical_treatmentMyocardial Ischemiamoderate ischemic mitral regurgitationCoronary Artery DiseaseCoronary artery diseaseInternal medicineMitral valvemedicineHumansMyocardial infarctionCoronary Artery BypassPropensity ScoreVentricular remodelingAgedMitral valve repairMitral regurgitationEjection fractionVentricular Remodelingbusiness.industryMitral Valve InsufficiencyMiddle Agedmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureEchocardiographyExercise TestCardiologyFemaleSurgeryCardiology and Cardiovascular MedicinebusinessArtery
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Compliance and Pulse Wave Velocity Assessed by MRI Detect Early Aortic Impairment in Young Patients With Mutation of the Smooth Muscle Myosin Heavy C…

2008

Purpose To evaluate aortic elasticity with MRI on young asymptomatic individuals with mutation of the smooth muscle myosin heavy chain in whom aortic enlargement is not present. Materials and Methods Aortic compliance, aortic distensibility, and pulse wave velocity (PWV) were semiautomatically measured from MRI in 8 asymptomatic subjects having a mutation of the MYH11 gene (M+) and 21 nonmutated relatives (M−) of similar age, sex, and blood pressure characteristics. Results Despite a similar aortic diameter in both groups, the aortic compliance and distensibility were significantly lower in M+ subjects compared with M− (0.84 ± 0.33 versus 2.03 ± 0.54 mm2/mmHg, 1.18 ± 0.62 10−3 versus 5.11 ±…

MalePulsatile flow030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging0302 clinical medicinemagnetic resonance imaginggeneticsPulse wave velocityComputingMilieux_MISCELLANEOUSmedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingPrognosisPulsatile FlowAortic valve stenosiscardiovascular systemCardiologyElasticity Imaging TechniquesFemalemedicine.symptomAlgorithmsBlood Flow VelocityAdultmedicine.medical_specialtypulse wave velocityAortic Valve InsufficiencySensitivity and SpecificityAsymptomaticYoung Adult03 medical and health sciencesElastic Modulusmedicine.arteryInternal medicineImage Interpretation Computer-Assistedmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansGenetic Predisposition to DiseaseRadiology Nuclear Medicine and imagingAortaMyosin Heavy ChainsReceiver operating characteristicbusiness.industryReproducibility of ResultsMagnetic resonance imagingAortic Valve StenosisImage Enhancementmedicine.diseaseaortaBlood pressureMutationelasticitybusiness
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Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics

2018

International audience; Importance - The natural history and the management of patients with asymptomatic aortic stenosis (AS) have not been fully examined in the current era. Objective - To determine the clinical outcomes of patients with asymptomatic AS using data from the Heart Valve Clinic International Database. Design, setting, and participants - This registry was assembled by merging data from prospectively gathered institutional databases from 10 heart valve clinics in Europe, Canada, and the United States. Asymptomatic patients with an aortic valve area of 1.5 cm2 or less and preserved left ventricular ejection fraction (LVEF) greater than 50% at entry were considered for the prese…

MaleRegistrieUnited StateCanadamedicine.medical_specialty030204 cardiovascular system & hematologyAsymptomaticSudden deathDisease-Free Survival03 medical and health sciences0302 clinical medicineAortic valve replacementRetrospective StudieInternal medicinemedicineHumansProspective StudiesRegistries030212 general & internal medicineHeart valveWatchful WaitingProspective cohort studyRetrospective StudiesAgedAged 80 and overAsymptomatic DiseaseEjection fractionbusiness.industryDisease ManagementAortic Valve StenosisMiddle Agedmedicine.diseaseAortic Valve StenosiUnited States3. Good healthEuropeProspective StudieStenosisDeath Sudden Cardiacmedicine.anatomical_structureAortic valve stenosisAsymptomatic DiseasesCardiology[SDV.IB]Life Sciences [q-bio]/BioengineeringFemalemedicine.symptombusinessCardiology and Cardiovascular MedicineHuman
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Modified Danielson Technique for Prosthetic Aortic Valve Endocarditis and Aortoventricular Discontinuity

2020

Endocarditis is a devastating complication of prosthetic aortic valve replacement. The infective process can destroy aortic annulus tissue, making conventional surgical valve replacement difficult or impossible and causing aortoventricular discontinuity. Several treatment techniques have been proposed. One of these, the Danielson technique, involves translocating the aortic valve to the native ascending aorta, débriding the abscess cavity, closing the coronary ostia, and bypassing the coronary arteries with a Y anastomosis between 2 vein grafts. We describe our use of a modified Danielson technique in a 68-year-old man with advanced prosthetic valve endocarditis that was associated with aor…

MaleReoperationAortic valvemedicine.medical_specialtyProsthesis-Related Infectionsmedicine.medical_treatmentAnastomosisValve replacementAortic valve replacementmedicine.arteryAscending aortaHumansMedicineEndocarditisCardiac skeletonCardiac Surgical ProceduresAgedbusiness.industryEndocarditis Bacterialmedicine.diseaseTechniquesSurgeryCoronary arteriesmedicine.anatomical_structureEchocardiographyAortic ValveHeart Valve Prosthesiscardiovascular systemCardiology and Cardiovascular MedicinebusinessTexas Heart Institute Journal
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Chronic Urticaria After Implantation of a Mitral Annuloplasty Ring in a Nickel-Allergic Patient

2017

MaleReoperationNickel allergymedicine.medical_specialtyMitral Valve AnnuloplastyUrticariaImmunology030204 cardiovascular system & hematologyProsthesis DesignImmunoglobulin E03 medical and health sciences0302 clinical medicineMitral annuloplasty ringDevice removalNickelMitral valve annuloplastyInternal medicineHumansImmunology and AllergyMedicineProsthesis designDevice RemovalChronic urticariaHeart Valve Prosthesis Implantationbiologybusiness.industryMiddle AgedPatch TestsSurgeryChronic diseaseHeart Valve ProsthesisChronic DiseaseDermatitis Allergic ContactCardiologybiology.proteinMitral Valvebusiness030217 neurology & neurosurgeryJournal of Investigational Allergology and Clinical Immunology
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Supracoronary ascending aortic replacement in patients with acute aortic dissection type A: What happens to the aortic root in the long run?

2013

ObjectiveOur objective was to determine long-term outcome predictors for patients with acute aortic dissection type A (AADA) and aortic root involvement.MethodsFrom 2001 through 2009, 119 of 152 patients operated on for AADA at a tertiary medical center underwent supracoronary ascending aortic replacement (52 women; mean age, 61 ± 15 years). Those with at least 1-year follow-up (n = 97) were retrospectively assessed for preoperative aortic root disease. Follow-up data were assessed for evidence of new-onset aortic root disease by computed tomography and echocardiography, and for reoperation for aortic root disease.ResultsMedian follow-up was 33.8 months (range, 0-112 months). Twenty-six (27…

MaleReoperationPulmonary and Respiratory Medicinemedicine.medical_specialtyTime FactorsAortic rootAortic Valve InsufficiencyComputed tomographyKaplan-Meier EstimateDissection (medical)Independent predictorAortographySeverity of Illness IndexNew onsetTertiary Care CentersBlood Vessel Prosthesis ImplantationPredictive Value of TestsRisk FactorsInternal medicineOdds RatiomedicineHumansIn patientAgedRetrospective StudiesUltrasonographyAortic dissectionmedicine.diagnostic_testbusiness.industryMean ageMiddle AgedSinus of Valsalvamedicine.diseaseAortic AneurysmSurgeryAortic DissectionLogistic ModelsTreatment OutcomeAcute DiseaseMultivariate Analysiscardiovascular systemCardiologyFemaleSurgeryTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessDilatation PathologicThe Journal of Thoracic and Cardiovascular Surgery
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