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showing 10 items of 6927 documents

Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspec…

2019

Abstract Corylus avellana (hazelnut) is one of the most popular tree nuts on a worldwide basis. The main products of C. avellana are kernels, a nutritious food, with a high content of healthy lipids, contained in a hard shell. In recent years, along with the ongoing research carried out on hazelnut kernels, a growing interest has been addressed to the hazelnut byproducts including hazelnut skin, hazelnut hard shell, and hazelnut green leafy cover as well as hazelnut tree leaf. These byproducts deriving from the roasting, cracking, shelling/hulling, and harvesting processes have been found as a source of “phytochemicals” with biological activity. The aim of this review is to provide a compre…

phenolicsPharmaceutical ScienceAntineoplastic Agents01 natural sciencesNutritious foodAnalytical ChemistryHuman healthCorylusAnti-Infective AgentsBetulaceaeDrug Discoveryanalytical tools; Betulaceae; biological activities; Corylus avellana; diarylheptanoids; phenolics; taxanes; Animals; Anti-Infective Agents; Antineoplastic Agents; Antipain; Corylus; Humans; Nuts; Plant ExtractsAnimalsAntipainHumansNutsFood scienceHazelnut treeBeneficial effectsRoastingPharmacology010405 organic chemistryChemistryPlant ExtractsOrganic Chemistrybiological activitiestaxanes0104 chemical sciences010404 medicinal & biomolecular chemistrydiarylheptanoidsComplementary and alternative medicineMolecular Medicineanalytical toolsCorylus avellana
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Subjective stress, objective heart rate variability-based stress, and recovery on workdays among overweight and psychologically distressed individual…

2015

Background: The present study aimed to investigate how subjective self-reported stress is associated with objective heart rate variability (HRV)-based stress and recovery on workdays. Another aim was to investigate how physical activity (PA), body composition, and age are associated with subjective stress, objective stress, and recovery. Methods: Working-age participants (n = 221; 185 women, 36 men) in this cross-sectional study were overweight (body mass index, 25.3-40.1 kg/m(2)) and psychologically distressed (>= 3/12 points on the General Health Questionnaire). Objective stress and recovery were based on HRV recordings over 1-3 workdays. Subjective stress was assessed by the Perceived St…

physical activityPerceived Stress Scaleobjective stressOverweightToxicologyBody fat percentageRecoveryHeart rate variabilityMedicineMETABOLIC SYNDROMEASSOCIATIONSphysiological stress2. Zero hungerheart rate variabilityJOB STRAINEFFORT-REWARD IMBALANCEObjective stressRELIABILITYmedicine.symptomSafety ResearchBioelectrical impedance analysismedicine.medical_specialty515 PsychologyStress assessmentAPPLICABILITYrecoveryperceived stress scalestress assessmentpsychological stressMETAANALYSISHeart rate variabilitysubjective stressWork-related stressJob strainPhysical activitybusiness.industryResearchAMBULATORY BLOOD-PRESSUREPublic Health Environmental and Occupational HealthCARDIOVASCULAR-DISEASE RISK3141 Health care sciencePerceived stress scalePHYSICAL-ACTIVITYPsychological stressPhysiological stresswork-related stressPhysical therapySubjective stressGeneral Health QuestionnairebusinessBody mass indexJournal of Occupational Medicine and Toxicology
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Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia

2022

Drug resistance is the ability of cancer cells to gain resistance to both conventional and novel chemotherapy agents, and remains a major problem in cancer therapy. Resistance mechanisms are multifactorial and involve more strictly pharmacological factors, such as P-glycoprotein (P-gp) and biological factors such as inhibitor of apoptosis proteins (IAPs) and the nuclear factor-kappa B (NF-κB) pathway. Possible therapeutic strategies for the treatment of acute myeloid leukemia (AML) have increased in recent years; however, drug resistance remains a problem for most pa-tients. Phytol and heptacosane are the major compounds of Euphorbia intisy essential oil (EO) which were demonstrated to inhi…

phytolmultidrug resistanceP-gp inhibitorDrug DiscoveryP-glycoprotein; multidrug resistance; acute myeloid leukemia cell; P-gp inhibitors; phytol; heptacosaneheptacosaneSettore BIO/14 - FarmacologiaPharmaceutical ScienceMolecular MedicineP-glycoproteinSettore CHIM/08 - Chimica Farmaceuticaacute myeloid leukemia cell
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I piani nazionali di ripresa e resilienza in prospettiva comparata

2021

L’articolo propone un’analisi dei piani di ripresa e resilienza di Francia, Germania, Italia, Spagna, Grecia e Portogallo. Per ogni caso di studio si prendono in considerazione vari elementi. Innanzitutto, è oggetto di disamina il contesto economico nel quale è calato il singolo piano, con un approfondimento sull’impatto della pandemia sulle finanze di ciascun Paese. Successivamente, si dà conto delle dimensioni e delle caratteristiche del piano. In particolare, si esaminano la portata finanziaria complessiva del piano, i settori in cui sono concentrate le risorse, la ripartizione dei finanziamenti previsti tra sovvenzioni e prestiti. Si ricostruisce, inoltre, il modello di governance di og…

piani di ripresa e resilienza analisi comparataSettore IUS/10 - Diritto Amministrativorecovery and resilience plans comparative analysis
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Recovery of pickling acid solutions by membrane technology: the EU REWACEM Project

2017

Resource recovery from industrial waste water by cutting edge membrane technologies

pickling recovery of hydrochloric acid
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Deepening Inside the Pictorial Layers of Etruscan Sarcophagus of Hasti Afunei: An Innovative Micro-Sampling Technique for Raman/SERS Analyses

2019

The Hasti Afunei sarcophagus is a large Etruscan urn, made up of two chalky alabaster monoliths. Dated from the last quarter of the third century BC, it was found in 1826 in the small town of Chiusi (Tuscany- Il Colle place) by a landowner, Pietro Bonci Casuccini, who made it part of his private collection. The noble owner&rsquo

pictorial layerSmall townmedia_common.quotation_subjectPharmaceutical ScienceColor02 engineering and technologyengineering.materialmadder lakeSpectrum Analysis Raman01 natural sciencesArticlesarcophagusSERS analysesAnalytical Chemistrylcsh:QD241-441Egyptian bluechemistry.chemical_compoundImaging Three-Dimensionallcsh:Organic chemistryDrug Discoverymicrosampling techniquepictorial layer; Etruscan; sarcophagus; SERS analyses; Egyptian blue; madder lake; microsampling techniquePhysical and Theoretical ChemistryIconographyColoring Agentsmedia_common010401 analytical chemistryOrganic ChemistrySettore CHIM/06 - Chimica OrganicaArt021001 nanoscience & nanotechnologyArchaeology0104 chemical sciencesCultural heritageAlabasterchemistryArchaeologyItalyChemistry (miscellaneous)Egyptian blueMicro samplingengineeringMolecular MedicineMicrotechnologyPrivate collectionSarcophagus0210 nano-technologyEtruscanSarcophaguMolecules
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A giant planet beyond the snow line in microlensing event OGLE-2011-BLG-0251

2013

We present the analysis of the gravitational microlensing event OGLE-2011-BLG-0251. This anomalous event was observed by several survey and follow-up collaborations conducting microlensing observations towards the Galactic Bulge. Based on detailed modelling of the observed light curve, we find that the lens is composed of two masses with a mass ratio q=1.9 x 10^-3. Thanks to our detection of higher-order effects on the light curve due to the Earth's orbital motion and the finite size of source, we are able to measure the mass and distance to the lens unambiguously. We find that the lens is made up of a planet of mass 0.53 +- 0.21,M_Jup orbiting an M dwarf host star with a mass of 0.26 +- 0.…

planets and satellites: detection010504 meteorology & atmospheric sciencesSatellitesbulge [Galaxy]FOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsDiscoveryGravitational microlensing01 natural sciencesGalaxy: bulgeEinstein radiusLensgravitational lensing: weakSettore FIS/05 - Astronomia e AstrofisicaPlanetSnow0103 physical sciencesgravitational lensing; weak; planets and satellites; detection; planetary systems; Galaxy; bulgegravitational lensing: weak; planets and satellites: detection; planetary systems; Galaxy: bulgeBinaryQB Astronomy010303 astronomy & astrophysicsplanetary systemsAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesQBPhysicsEarth and Planetary Astrophysics (astro-ph.EP)Giant planetSystemsSearchAstronomy and AstrophysicsRadiusFrequencyPlanetary systemMass ratioMassLight curveStarsAlgorithmdetection [Planets and satellites]Planetary systemsSpace and Planetary ScienceDwarfAstrophysics::Earth and Planetary Astrophysicsweak [Gravitational lensing]Astrophysics - Earth and Planetary AstrophysicsAstronomy and Astrophysics
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Effects of arbuscular mycorrhizal symbiosis on the nitrogen uptake of three durum wheat genotypes from two different organic sources

2012

plant genotypearbuscular mycorrhizal symbiosi15N-Nitrogen recoveryorganic matterSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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Targeted Drug Delivery in Plants: Enzyme‐Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevine Trunk Disease Esca

2019

Abstract Nanocarrier (NC)‐mediated drug delivery is widely researched in medicine but to date has not been used in agriculture. The first curative NC‐based treatment of the worldwide occurring grapevine trunk disease Esca, with more than 2 billion infected plants causing a loss yearly of $1.5 billion, is presented. To date, only repetitive spraying of fungicides is used to reduce chances of infection. This long‐term treatment against Esca uses minimal amounts of fungicide encapsulated in biobased and biodegradable lignin NCs. A single trunk injection of <10 mg fungicide results in curing of an infected plant. Only upon Esca infection, ligninolytic enzymes, secreted by the Esca‐associated fu…

plant protectionminiemulsionGeneral Chemical EngineeringGeneral Physics and AstronomyMedicine (miscellaneous)02 engineering and technologyBiology010402 general chemistry01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)Toxicologychemistry.chemical_compoundLigninGeneral Materials Sciencegrapevine trunk diseasesVitis viniferalcsh:Scienceagriculture2. Zero hungerchemistry.chemical_classificationFull PapernanocarriersfungiGeneral Engineeringfood and beveragesFull Papers021001 nanoscience & nanotechnology3. Good health0104 chemical sciencesFungicideEnzymechemistryTargeted drug deliveryCurative treatmentDrug deliverylcsh:QNanocarriers0210 nano-technology
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Drug Delivery in Plants: Targeted Drug Delivery in Plants: Enzyme-Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevin…

2019

In article number 1802315, Jochen Fischer, Frederik R. Wurm, and co‐workers report the first nanocarrier‐mediated drug delivery in plants. Enzyme‐degradable lignin nanocarriers are injected into the trunks of grapevine plants. They release a fungicide selectively inside of the plants and are able to cure the worldwide fungal plant disease Esca for the first time. This strategy will reduce the extensive spraying of pesticides in agriculture. Image credit: Katharina Maisenbacher.

plant protectionminiemulsionInside Back CoverGeneral Chemical EngineeringGeneral Physics and AstronomyMedicine (miscellaneous)DiseasePharmacologyBiochemistry Genetics and Molecular Biology (miscellaneous)chemistry.chemical_compoundLigninMedicineGeneral Materials Sciencegrapevine trunk diseasesagriculturechemistry.chemical_classificationnanocarriersbusiness.industryfungiGeneral Engineeringfood and beveragesEnzymechemistryTargeted drug deliveryCurative treatmentDrug deliveryNanocarriersbusinessAdvanced Science
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