Search results for "viral"
showing 10 items of 2737 documents
Medical masks and Respirators for the Protection of Healthcare Workers from SARS-CoV-2 and other viruses
2020
The use of medical masks and respirators as personal protective equipment is pivotal to reducing the level of biological hazard to which healthcare workers are exposed during the outbreak of highly diffusible pathogens, such as the recent novel coronavirus SARS-CoV-2. Unfortunately, during this pandemic, supplies are rapidly running out worldwide, with potential consequences for the rate of occupational infections. Also, knowledge about specific characteristics of respirators is of utmost importance to select the proper type according to the clinical setting. A wide variety of literature is available on the topic, but mostly based on Influenza viruses infection models. Clinical evidence on …
Study of the interactions between Broad bean wilt virus 1 and its host plants
Broad bean wilt virus 1 (BBWV-1) is the type member of the Fabavirus genus, in the Secoviridae family. BBWV-1 is worldwide distributed and infects important horticultural and ornamental crops causing considerable economic losses. However, information about the biological and molecular characteristics of BBWV-1 isolates is scarce. BBWV-1 is composed of two molecules of positive single-stranded RNA (ssRNA+) that are separately encapsidated in virions of icosahedral morphology. Each ssRNA+ encodes polyproteins which are processed by proteolytic cleavage into functional peptides. RNA1 (~ 5.8 kb) encodes for one polyprotein that renders proteins involved in viral replication: a protease cofactor…
New developments in the management of hepatitis C virus infection: focus on boceprevir
2012
Chronic hepatitis C virus infection is an important public health problem, and the standard treatment (combination of pegylated interferon-α and ribavirin) has an effectiveness rate of only 40%-50%. Novel virus-specific drugs have recently been designed, and multiple compounds are under development. The approval for the clinical use of direct-acting antivirals in 2011 (boceprevir [BOC] and telaprevir, viral NS3 protease inhibitors) has increased recovery rates by up to 70%. Therefore, a highly effective treatment has been envisioned for the first time. This paper focuses on BOC and the implementation of new BOC-based treatment regimes.
Meme marketing: How marketers can drive better engagement using viral memes?
2022
Scholars and industry stakeholders have exhibited an interest in identifying the underlying dimensions of viral memes. However, the recipe for creating a viral meme remains obscure. This study makes a phenomenological contribution by examining viral memes, exploring the antecedents (i.e., content-related factors, customer-related factors, and media-related factors), consequences, and moderating factors using a mixed-method approach. The study presents a holistic framework for creating viral memes based on the perceptions of customers and industry stakeholders. Four quantitative studies (i.e., a lab experiment, an online quasi-experiment, an event study, and a brand recall study) validate th…
Cultural Contagion from Micro to Macro: A Semiopragmatics Approach
2017
International audience; Although cultures are a group-based process, cultural change occurs on the level of the individual, through micro-level interactions which give rise to new representations. Based on the semiopragmatics approach to communications, this contribution will theorize this process of cultural evolution, linked to the phenomenon of contagion, notably assisted by media and internet-based communication, based on examples of recent emerging cultural trends.
L’irrespect sur les réseaux socionumériques
2018
La viralité dans l’espace public numérique
2018
Depuis 2007 et la campagne électorale de Ségolène Royal, « Désir d’avenir », les communicants, les militants et les activistes utilisent la potentialité des dispositifs sociotechniques au service de leur candidat et de la propagation de leurs idées. Les réseaux sociaux ont profondément changé la stratégie de communication des équipes de campagne qui ont préempté l’espace numérique en multipliant leur présence social (Facebook, Twitter, Instagram, etc.). Souvent composées de digital natives et d’individus maitrisant les codes et les rites en vigueur sur ces dispositifs, les équipes intègrent la force du canal de communication afin de renouveler la relation et la communication entre le politi…
An ancient virus type from extreme environments
2014
Nonlinearities in plant RNA virus fitness
2012
Una de las mayores amenazas tanto para la salud humana y animal, como para la agronomía es la emergencia de nuevas enfermedades infecciosas, la mayoría de las cuales están causadas por los virus de RNA. La emergencia viral es un problema complejo que consista en la adquisición de la variación genética, por mutación o recombinación, dentro de la población viral en el huésped reservorio la cual podría facilitar la capacidad de infectar de manera eficiente nuevos huéspedes. Los virus de RNA presentan a una evolucionabilidad extraordinaria por sus grandes tamaños poblacionales, cortos tiempos de generación y altas tasas de mutación y recombinación. Comprender los mecanismos evolutivos que podrí…
The interplay between the host microbiome and pathogenic viral infections
2021
The microorganisms associated with an organism, the microbiome, have a strong and wide impact in their host biology. In particular, the microbiome modulates both the host defense responses and immunity, thus influencing the fate of infections by pathogens. Indeed, this immune modulation and/or interaction with pathogenic viruses can be essential to define the outcome of viral infections. Understanding the interplay between the microbiome and pathogenic viruses opens future venues to fight viral infections and enhance the efficacy of antiviral therapies. An increasing number of researchers are focusing on microbiome-virus interactions, studying diverse combinations of microbial communities, …