Search results for "visual_art"

showing 10 items of 2987 documents

3-acetylaltholactone and related styryl-lactones, mitochondrial respiratory chain inhibitors.

2000

A novel furano-pyrone, 3-acetylaltholactone, and two other known styryl-lactones, altholactone and 5-acetoxyisogoniothalamin oxide, have been isolated from Goniothalamus arvensis (Annonaceae) stem bark. We report here the isolation and structural elucidation of these compounds with furane-pyrone and styryl-pyrone skeletons, postulating also for the first time their mechanism of cytotoxicity based on inhibition on mammalian mitochondrial respiratory chain.

Models MolecularStereochemistryChemical structureSubmitochondrial ParticlesMolecular ConformationPlant ScienceHorticultureBiochemistryMitochondria HeartStyrenesLactonesOxygen ConsumptionAnimals3-acetylaltholactoneCytotoxicityFuransMolecular BiologyGoniothalamusStem barkPlants MedicinalbiologyMolecular StructurePlant StemsUncoupling AgentsGeneral Medicinebiology.organism_classificationNADKineticsMitochondrial respiratory chainAnnonaceaePyronesvisual_artvisual_art.visual_art_mediumBarkCattlePhytochemistry
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Hydrogen and copper ion-induced molecular reorganizations in scorpionand-like ligands. A potentiometric, mechanistic, and solid-state study.

2007

Two aza scorpionand-like macrocycles (L2 and L3) have been prepared. L2 consists of a tren amine with two of its arms cyclizized with a 2,6-bis(bromomethyl)pyridine. In L3, the remaining pendant arm has been further functionalized with a fluorophoric naphthalene group. X-ray data on the compounds [H(L3)]ClO4.H2O (1) and [H3(L3)](H2PO4)3.H2O (2) as well as solution studies (pH-metry, UV-vis, and fluorescence data) show the movement of the pendant arm as a result of the protonation degree of the macrocycles and of the formation of intramolecular hydrogen bonds. X-ray data on the complexes [Cu(L2)](ClO4)2]2.H2O (3) and [Cu(L3)](ClO4)2 (4) and solution studies on Cu2+ coordination show the impl…

Models MolecularStereochemistryPotentiometric titrationProtonationLigandsInorganic ChemistryMetalchemistry.chemical_compoundX-Ray DiffractionPyridinePolymer chemistryMoleculePhysical and Theoretical ChemistryIonsMolecular StructureHydrogen bondWaterHydrogen-Ion ConcentrationPhosphorus AcidsKineticschemistryvisual_artIntramolecular forcevisual_art.visual_art_mediumPotentiometryAmine gas treatingCopperHydrogenInorganic chemistry
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Development of Bimetallic Titanocene−Ruthenium−Arene Complexes As Anticancer Agents: Relationships between Structural and Biological Properties

2010

A series of bimetallic titanium-ruthenium complexes of general formula [(η(5)-C(5)H(5))(μ-η(5):κ(1)-C(5)H(4)(CR(2))(n)PR'R'')TiCl(2)](η(6)-p-cymene)RuCl(2) (n = 0, 1, 2 or 4; R = H or Me; R' = H, Ph, or Cy; R'' = Ph or Cy) have been synthesized, including two novel compounds as well as two cationic derivatives of formula [(η(5)-C(5)H(5))(μ-η(5):κ(1)-C(5)H(4)(CH(2))(n)PPh(2))TiCl(2)] [(η(6)-p-cymene)RuCl](BF(4)) (n = 0 or 2). The solid state structure of two of these compounds was also established by X-ray crystallography. The complexes showed a cytotoxic effect on human ovarian cancer cells and were markedly more active than their Ti or Ru monometallic analogues titanocene dichloride and RA…

Models MolecularStereochemistrychemistry.chemical_elementAntineoplastic AgentsCrystal structureCrystallography X-RayRutheniumCathepsin BMetalStructure-Activity Relationshipchemistry.chemical_compoundCoordination ComplexesCell Line TumorDrug DiscoveryAnimalsHumansBimetallic stripAlkylTitaniumchemistry.chemical_classificationCationic polymerizationTitanocene dichlorideRutheniumEnzymechemistryDrug Resistance Neoplasmvisual_artvisual_art.visual_art_mediumMolecular MedicineCattleDrug Screening Assays AntitumorProtein BindingJournal of Medicinal Chemistry
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Synthetically persistent, self assembled [V(IV)2V(V)4] polyoxovanadates: facile synthesis, structure and magnetic analysis.

2011

Slow diffusion in a H-tube at room temperature of a methanolic solution of [VO(acac)(2)] (Hacac = acetylacetone) and 1,10-phenanthroline (phen) or 2,2'-bipyridine (bipy) into an aqueous solution of sodium pyrophosphate (Na(4)P(2)O(7)) resulted in the serendipitous formation of X-ray quality crystals of mixed-valent, hexameric oxovanadates of general formula [V(6)O(12)(OCH(3))(4)(L)(4)]·solv [L = 1,10-phenanthroline (phen) for 1· 2CH(3)OH · 4H(2)O (1a), and 2,2'-bipyridine (bipy) for 2· 4H(2)O (2a)]. These were characterized by single-crystal X-ray diffraction, IR, elemental and thermogravimetric analysis (TGA). A facile, rationalized synthetic route for the isolation of 1a and 2a could be e…

Models MolecularThermogravimetric analysisAqueous solutionChemistryStereochemistryAcetylacetoneMagnetic PhenomenaMolecular ConformationCrystal structureHydrogen-Ion Concentrationlaw.inventionInorganic ChemistryCrystalMetalCrystallographychemistry.chemical_compoundlawvisual_artvisual_art.visual_art_mediumSolventsMoleculeCrystallizationVanadatesDalton transactions (Cambridge, England : 2003)
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A Tetracopper(II)-Tetraradical Cuboidal Core and Its Reactivity as a Functional Model of Phenoxazinone Synthase

2007

The coordination chemistry of the tridentate ligand N-(2-hydroxy-3,5-di-tert-butylphenyl)-2-aminobenzylalcohol H3L has been studied with the copper(II) ion. The ligand is noninnocent in the sense that it is readily oxidized in the presence of air to its o-iminobenzosemiquinonato [L*]2- radical form. The crystal structure of the synthesized tetracopper(II)-tetraradical complex [CuII4(L*)4] (1), has been determined by X-ray crystallography at 100 K. Variable-temperature (2-290 K) magnetic susceptibility measurements of complex 1 containing eight paramagnetic centers establish the spin ground state to be diamagnetic (St=0) arising from the antiferromagnetic interactions. Electrochemical measur…

Models Molecularchemistry.chemical_classificationSpectrometry Mass Electrospray IonizationMagnetic Resonance SpectroscopySpectrophotometry InfraredLigandChemistryStereochemistryCrystal structureCrystallography X-RayMagnetic susceptibilityCoordination complexInorganic ChemistryMetalMagneticsCrystallographyParamagnetismvisual_artElectrochemistryvisual_art.visual_art_mediumAntiferromagnetismReactivity (chemistry)Physical and Theoretical ChemistryOxidoreductasesCopperInorganic Chemistry
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Thermodynamic studies of actinide complexes. 1. A reappraisal of the solution equilibria between plutonium(IV) and ethylenediaminetetraacetic acid (E…

2007

Abstract A detailed reevaluation of the complexation equilibria of plutonium(IV) with the polyaminocarboxylic sequestering agent EDTA4− has been performed in 1 M (H,K)NO3 media at 298 K by means of visible absorption spectrophotometry and glass-electrode potentiometry at millimolar concentration levels. The high binding affinity even under strongly acidic conditions supports the exclusive formation of the neutral Pu(EDTA) complex over the range 0.01 ≤ [H+] ≤ 0.9 M with an apparent formation constant of log β110 = 25.8(1) at 0.9 M HNO3. Extrapolation to zero ionic strength using the SIT approach provides the first ever-reported NEA–TDB compliant estimate of β 110 0 ( log β 110 0 = 32.2 ( 3 )…

Molar concentrationEDTA complexesGeneral Chemical EngineeringPotentiometric titrationEthylenediaminetetraacetic acid010402 general chemistry01 natural sciencesMetalchemistry.chemical_compoundSpectrophotometrymedicinespectrophotometryComputingMilieux_MISCELLANEOUSmedicine.diagnostic_testactinides010405 organic chemistryplutonium(IV) complexessolution thermodynamicsGeneral ChemistrySolubility equilibrium0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistrychemistryspeciationIonic strengthStability constants of complexespotentiometryvisual_art[ CHIM.THEO ] Chemical Sciences/Theoretical and/or physical chemistryvisual_art.visual_art_mediumNuclear chemistry
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The turnover of dental microwear texture: Testing the" last supper" effect in small mammals in a controlled feeding experiment

2020

Dental microwear texture (DMT) analysis is commonly applied for dietary reconstruction of vertebrates. The temporal scale on which dietarily informative microscopic wear forms on enamel surfaces is crucial to infer dietary flexibility and seasonality. Microwear is assumed to form shortly before the individual's death, reflecting information pertaining to the last meals consumed (“last supper” effect). In primate feeding experiments, microwear features formed within hours, suggesting rates of turnover within one to two weeks. As DMT formation experiments testing the persistence of microwear three-dimensionally (textures) are still lacking, we test how quickly DMTs form and pr…

Molar010506 paleontology10253 Department of Small AnimalsDiet switchEvolutionDental Wear1904 Earth-Surface ProcessesTexture (music)010502 geochemistry & geophysicsOceanography01 natural sciencesMandibular second molarAnimal scienceBehavior and Systematics1910 OceanographyEcology Evolution Behavior and Systematics0105 earth and related environmental sciencesEarth-Surface Processes2. Zero hungerEnamel paint630 AgricultureEcologyPalaeontologyPaleontologyEarth1911 Paleontology1105 Ecology Evolution Behavior and SystematicsSurface Processesvisual_artvisual_art.visual_art_medium570 Life sciences; biologyGeology
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Everything matters: Molar microwear texture in goats (Capra aegagrus hircus) fed diets of different abrasiveness

2020

There is an ongoing discourse about whether or not external abrasives influence the microscopic wear in herbivore teeth, including a statement that “dust does not matter”. We submitted the maxillary and mandibular second molar of 28 goats (Capra aegagrus hircus) to dental microwear texture analysis (DMTA). The study animals were divided into four groups, which received diets of increasing phytolith-based abrasiveness (L: lucerne based pellets, very low phytolith abrasion diet, acting as control; G: grass-based pellets, medium abrasive phytolith diet; GR: grass and rice husk pellets, high abrasion phytolith diet), or a diet with added external abrasives (GRS: the GR diet with add…

Molar010506 paleontology10253 Department of Small AnimalsEvolutionPhytolith1904 Earth-Surface ProcessesGrazerGrit010502 geochemistry & geophysicsOceanography01 natural sciencesMesowearMesowearAnimal scienceBehavior and SystematicsGrazing1910 Oceanographymedia_common.cataloged_instanceEcology Evolution Behavior and Systematics0105 earth and related environmental sciencesEarth-Surface Processesmedia_common2. Zero hungerEnamel paintbiology630 AgricultureEcologyPalaeontologyTooth wearPaleontologyEarthbiology.organism_classification1911 Paleontology1105 Ecology Evolution Behavior and SystematicsTexture analysisConnochaetes taurinusSurface ProcessesTooth wearPhytolithvisual_artvisual_art.visual_art_medium570 Life sciences; biologyGeologyGiraffa camelopardalis
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Modulation of metallothionein and metal partitioning in liver and kidney of Solea senegalensis after long-term acclimation to two environmental tempe…

2014

9 pages, 3 figures, 5 tables

MolarAcclimatizationchemistry.chemical_elementBioconcentrationKidneyBiochemistryAcclimatizationMetalSeleniummedicineAnimalsMetallothioneinInductively coupled plasma mass spectrometryBenthic fishGeneral Environmental ScienceKidneyTemperaturesChemistryTemperaturemedicine.anatomical_structureLiverMetalsvisual_artEnvironmental chemistryFlatfishesvisual_art.visual_art_mediumMetallothioneinFood AnalysisSeleniumEnvironmental Research 132: 197-205 (2014)
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Optical magnification has no benefits on the detection of occlusal caries lesions in permanent molars using different visual scoring systems: An in v…

2020

Background Some studies have addressed the influence of optical magnification on the detection of caries lesions using a visual scoring system. However, there is a lack of research related to the use of the CAST and ADA-CCS visual scoring systems. In addition, the reliability and accuracy of ADA-CCS index in permanent teeth were not studied yet. So, the aim of this study was to evaluate, in vitro, the influence of different levels of optical magnification on the detection of occlusal caries lesions in permanent molars using three visual scoring systems. Material and Methods One occlusal site per tooth was analyzed in 120 extracted permanent molars. Two trained examiners inspected the teeth …

MolarCaries detectionMagnificationMagnification03 medical and health sciences0302 clinical medicinestomatognathic systemDentinmedicineVisual examination030212 general & internal medicineGeneral DentistryPermanent teethOrthodonticsReproducibilityEnamel paintbusiness.industryResearchOcclusal caries030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Community and Preventive Dentistrystomatognathic diseasesmedicine.anatomical_structurevisual_artUNESCO::CIENCIAS MÉDICASDental cariesvisual_art.visual_art_mediumPermanent teethbusinessOperating microscopeJournal of Clinical and Experimental Dentistry
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