Search results for "wt"

showing 10 items of 5424 documents

Effects of combined hormone replacement therapy or its effective agents on the IGF-1 pathway in skeletal muscle.

2010

Objectives To investigate the effects of combined hormone replacement therapy (HRT) and its effective agents on the IGF-1 signaling pathway. Design and methods To examine the effects of HRT on skeletal muscle in vivo, we utilized pre- and post-intervention samples from a randomized double blinded trial with 50–57-year-old women. The intervention included the year-long use of either HRT preparation (2 mg 17β-estradiol, E2; 1 mg norethisterone acetate, NETA, n = 10) or placebo (CO, n = 9). Microarray technology and quantitative PCR (qPCR) were used to study the expression of insulin-like growth factor I (IGF-1) and its splice variants as well as IGF-1 receptor, Akt1, mTOR, FOXO1, FOXO3, atrog…

estradioliTranscription GeneticEndocrinology Diabetes and MetabolismMuscle Fibers SkeletalEstrogen receptorpostmenopausal womenMuscle ProteinsFOXO1Receptor IGF Type 10302 clinical medicineEndocrinologyProtein IsoformsTestosteroneInsulin-Like Growth Factor IReceptorRandomized Controlled Trials as Topic0303 health sciencesEstradiolMyogenesisForkhead Box Protein O1TOR Serine-Threonine KinasesEstrogen Replacement TherapyForkhead Box Protein O3Forkhead Transcription FactorsMiddle Agedmedicine.anatomical_structureReceptors EstrogenReceptors AndrogenFemalemedicine.medical_specialtynorethisterone acetate030209 endocrinology & metabolismBiologypostmenopausaalinen nainen03 medical and health sciencesInternal medicinemedicineHumansnoretisteroniasetaattiluurankolihasskeletal muscleMuscle SkeletalProtein kinase BPI3K/AKT/mTOR pathway030304 developmental biologyhormonikorvaushoitoSKP Cullin F-Box Protein LigasesSkeletal muscleAndrogen receptorNorethindrone AcetateEndocrinologyHormone replacement therapyIGF-1 signalointiNorethindroneIGF-1 signalingProto-Oncogene Proteins c-aktGrowth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
researchProduct

Dewey, Hippie Communes, and Education

2021

Este artículo establece una conexión relevante entre la filosofía de la educación de John Dewey y las comunas hippies de los Estados Unidos durante los años sesenta y setenta. Después de analizar la filosofía de Dewey en el contexto de la contracultura de los años sesenta, el artículo resume y organiza la filosofía de Dewey en torno a los conceptos de crecimiento, experiencia, educación, democracia y ocupaciones. A continuación, el artículo recurre a siete textos autobiográficos que describen la vida en cinco comunas hippies diferentes, y los utiliza para ilustrar los fundamentos de la filosofía educativa de Dewey y de su significado contemporáneo. HAR2017-85230-R In this article I aim to e…

estudios culturalescontraculturaeducationsixties.democracyfilosofía de la educaciónoccupationsgrowthhippie communes:PEDAGOGÍA [UNESCO]UNESCO::PEDAGOGÍAJohn Dewey
researchProduct

Johtamisen eettiset konfliktit vahingoittavat työhyvinvointia suomalaisissa kasvuyrityksissä

2019

Kiinnostus eettistä johtamista eli johdon ja organisaation hyviä ja oikeudenmukaisia käytänteitä ja niiden vaikutuksia kohtaan on lisääntynyt. Eettinen johtaminen välittyy sekä työntekijöiden että asiakkaiden hyvinvointiin, ja se selittää jopa kolmanneksen organisaation innovaatiokyvystä. Epäeettinen toiminta ja sen tuottamat konfliktit taas aiheuttavat monia yksilöille, ryhmille ja organisaatioille epäedullisia seurauksia. nonPeerReviewed

ethicalityjohtaminenkasvuyrityksetconflicts (societal events)growth companieskonfliktitleadership (activity)eettisyys
researchProduct

Muistisairaan ihmisen kokemukset teknologiasta osana arkea - turvaa vai tunkeilevuutta

2018

Tässä tutkimuksessa selvitettiin muistisairaiden ihmisten arkea tukevan teknologian käyttöönottoa ja heidän sekä heidän läheistensä kokemuksia teknologian käytöstä. Tutkimuksen viitekehyksenä toimi Lawtonin ekologinen malli. Tutkimuksessa käytettiin etnografista näkökulmaa haastattelemalla ja havainnoimalla muistisairaita ihmisiä teknologian käyttötilanteissa. Ensimmäinen vaihe toteutettiin vuosina 2004-2007. Ensimmäisessä vaiheessa kohderyhmänä olivat 25 muistisairautta sairastavaa kotona yksin tai omaishoitajansa kanssa asuvaa henkilöä sekä heidän läheistään ja viisi vastaajaa kuntien kotihoidosta. Koteihin vietiin yhteensä 29 erilaista laitetta. Toinen keruuvaihe toteutettiin vuosina 201…

ethicalitykotihoitoLawtonin ekologinen mallitekniikka (laitteet)experienceomaishoitajatseurantaomaishoitomuistisairaudetautonomiapeople with dementiaapuvälineettracking technologymobilitystigmatliikkuvuusikääntyminensatelliittipaikannustechnologykokemuksetteknologiaetäseurantaliikkumineninsecuritymuistisairaatdementiaturvattomuus
researchProduct

The Influence of Student Abilities and High School on Student Growth: A Case Study of Chinese National College Entrance Exam

2019

Enabled by available educational data and data mining techniques, educational data analysis has become a hot topic. Current researches mainly focus on the prediction of problems and performance rather than revealing the underlying causal relationships. Based on a unique exam data, we extracted the abilities of examinee from HSEE (High School Entrance Exam) based on the knowledge of educational experts, then we measured student growth from middle school to high school in total score and subject scores. We studied the impact of high school ranking and student abilities of HSEE on student growth by multiple linear regression model, in which high school ranking is divided into 5 levels, Level 1…

evaluationGeneral Computer Scienceeducational data miningEducational dataeducationGeneral EngineeringEquity (finance)Multiple linear regression modelEducational data miningEntrance examRankingstudent abilityMathematics educationGeneral Materials ScienceActive listeninglcsh:Electrical engineering. Electronics. Nuclear engineeringElectrical and Electronic EngineeringStudent growthlcsh:TK1-9971high school ranking
researchProduct

Synthesis of Monodisperse Spherical Nanocrystals

2016

Nanoparticles, small units of matter with dimensions in the range 1-100 nm, exhibit many advantageous size-dependent magnetic, electrical, chemical and optical prop- erties, which are not observed at the microscale or bulk. These properties are extremely sensitive to particle size, and thus the ability to produce monodisperse particles is critical. Due to its ease of use and flexibility, precipitation of nanoparticles from solution is one of the most widely used synthesis methods. The main disadvantage of this method is that the relationship between particle growth and system conditions is not fully understood. In practice, the optimal reaction conditions are usually ascertained empirically…

evolution of the nanoparticle size distributionOstwald ripeningFlexibility (engineering)Materials sciencenanoparticle growthPrecipitation (chemistry)Dispersitysize focussing and defocussingNanoparticleCrystal growthparticle sizemonodisperse particlessymbols.namesakeNanocrystalChemical physicssymbolsNanoparticlesParticle size
researchProduct

Trattamento induratio penis plastica: benefici e svantaggi dell'extra-corporeal shock therapy (ESWT). Studio prospettico randomizzato v/s placebo.

2011

extra-corporeal shock therapy (ESWT)Trattamento induratio penis plasticaStudio prospettico randomizzato v/s placebo.Settore MED/24 - Urologia
researchProduct

Effects of weekend starvation and the duration of daily feeding on production parameters of rainbow trout Oncorhynchus mykiss

2021

It would often be practical to starve the cultivated fishes over the weekends, e.g. to save in labour costs. We evaluated the possibility that domesticated juvenile rainbow trout (Oncorhynchus mykiss) could compensate for the lost growth of the 2-day weekend starvation by either hyperphagic response and/or by lower feed conversion ratio, compared to the fish fed every day in an 8-week experiment. Rainbow trout (initial weight c. 30 g, temperature 16 °C) starved during the weekends were able to increase feed intake during the weekdays clearly above the intake of the control fish after the first two weekends, also seen as an increase of the compensation coefficients over the last four weeks o…

feed conversion ratiofeeding frequencykalanviljelyfastingkirjolohisalmonidsruokintalohikalatcompensation coefficientkasvupaastocompensatory growth
researchProduct

THE IMPACT OF FISCAL POLICY ON ECONOMIC GROWTH IN THE FOUNDING COUNTRIES OF THE EUROPEAN UNION

2015

Changes in fiscal policy have an impact on aggregate demand, the allocation of resources and income distribution. The present study highlights the impact of fiscal policy on the founding countries of the European Union in the period 2000-2011. The evolution of GDP / capita was explained using the structure of tax revenues, inflation, budget deficit and also qualitative variables like the economic crisis and weather conditions. The results of the analysis indicate that fiscal policy has a significant negative impact on the founding countries of the European Union, in particular through measures taken in respect of value added tax, excise duties, income taxes for households and corporations a…

fiscal policy economic growth budget deficit tax revenuesRevista Economica
researchProduct

FISCAL POLICY`S INFLUENCE ON ECONOMIC GROWTH IN THE EUROPEAN UNION

2012

In this paper we study the impact of the fiscal policy on the economic growth for European Union, for the period 2000-2009. This subject represents a very debated problem in the economic literature. Our findings shows that, from the analysis of correlation between economic growth rate and total rate of taxation, there is generally an inverse relationship, meaning that an increase in the tax rate adversely affects economic growth. Continuing the analysis of the correlation between economic growth rate and total tax rate components it can be seen that there is an inverse relationship between labor taxation and capital taxation and economic growth in EU Member States. Both labour and capital t…

fiscal policy economic growth taxes on labour taxes on capital taxes on consumption.jel:E62jel:H20health care economics and organizationsRevista economica
researchProduct