Search results for "wt"

Persistent joblessness and fertility intentions

2019

Background: The vast majority of demographic studies have approached and operationalised the notion of economic uncertainty using snapshot indicators. Hence, the complexity and diversity of individuals' employment careers were largely hidden. We posit that the persistence of joblessness - that is, repeated and close spells of joblessness - represents a crucial marker of economic uncertainty in the realm of fertility (intention) research. Objective: We aim to explore the association between persistent joblessness of both members of the couple and women's fertility intentions among those who entered employment at least once in the last five years. Methods: We develop an index of persistent jo…

Enseñanza de las ciencias : revista de investigación y experiencias didácticas

2006

Resumen basado en el de la publicación Resumen en inglés Se muestra el importante papel de uno de los instrumentos más comunes, el péndulo, en la construcción del paradigma newtoniano. Del análisis de algunas aplicaciones interesantes llevadas a cabo por los mejores científicos de ese tiempo, se concluye que el uso apropiado del péndulo en el aula puede ser una manera fácil de introducir la evolución histórica y epistemológica de conceptos físicos básicos. ESP

Association between genetic variations in the insulin/insulin-like growth factor (Igf-1) signaling pathway and longevity: a systematic review and met…

2013

Some studies have shown that polymorphisms in the insulin growth factor-1 (IGF-1) signaling pathway genes could influence human longevity. However, the results of different studies are often inconsistent. Our aim was to investigate by systematic review and meta-analysis the association of the common polymorphisms defining the genetic variability of the IGF-1 signaling pathway associated with human longevity. Eleven studies investigating the association between the polymorphisms in the IGF-1 signaling pathway genes (IGF-1, IGF-1 receptor (IGF-1R), Forkhead box O3A (FOXO3A) and Silent mating type Information Regulation 1 (SIRT1) and longevity were found and analyzed. The modelfree approach wa…

Exclusion of Saccharomyces kudriavzevii from a wine model system mediated by Saccharomyces cerevisiae.

2010

This study investigated the competition and potential hybrid generation between the species Saccharomyces cerevisiae and S. kudriavzevii in a wine-model environment. Our main goal was to understand why S. kudriavzevii has not been found in wine fermentations whilst their hybrids are present. Auxotrophic mutants (Ura(-) and Lys(-)) were used to favour the selection of hybrids and to specifically differentiate the two species in mixed fermentations carried out at different temperatures (17 °C, 24 °C and 31 °C). Both yeasts showed a reduction in their maximum specific growth rates in mixed fermentations, indicating a clear antagonistic effect between the two microorganisms. Temperature played …

Migrations, trauma and mental health: A literature update on psychological assessment

2020

Introduction Migrants and refugees often face potentially traumatic events and post-migratory stressors. Upon arrival in the host country, they can be referred to mental health services to assess the impact of their previous experiences. These cross-cultural clinical encounters may raise questions, particularly regarding the assessment of mental health using models based on Western conceptions of psychopathology. Objectives and method The objective of the present non-systematic review of the literature is to discuss the psychological evaluation of post-traumatic reactions in migrants and refugees. More specifically, we present current research on psychopathology, resilience and post-traumat…

Autosomal recessive severe dwarfism in a Sicilian girl: a new form of osteodysplastic primordial dwarfism?

1996

A new type of osteodysplastic primordial dwarfism is delineated in a 5- year-old female child with severe growth retardation of prenatal onset, gross skeletal changes, a non-Seckel facial phenotype, and presumed autosomal recessive inheritance.

Externalizing behavior problems and interest in reading as predictors of later reading skills and educational aspirations

2017

This study examined the developments in children’s externalizing problems and interest in reading during their first four years of school (Grades 1–4) and investigated whether this development predicted the children’s Grade 6 reading skills and educational aspirations. Data comprised (1) teachers’ ratings of externalizing problems and children’s (N = 642; 43% girls) self-ratings of their interest in reading, collected between Grades 1 and 4, and (2) measures of reading fluency and comprehension, and children’s self-reports of educational aspirations, collected at Grade 6. First, latent growth modeling showed that a higher level of externalizing problems in Grade 1 was associated with a lowe…

Does ICT Usage Erode Routine Occupations at the Firm Level?

2019

We present decompositions and regression analyses that evaluate the routinization hypothesis and occupational polarization at the firm level. We establish two important facts. First, the results for the increasing abstract and declining routine occupation shares of total wage bill are consistent with the routinization hypothesis at the firm level. Second, the observed changes coincide with the usage of ICT in firms. This implies that disappearing middle-level (routine) work can be traced to firm-level technological change. Peer reviewed

Data from: Predator–vole interactions in northern Europe: the role of small mustelids revised

2014

The cyclic population dynamics of vole and predator communities is a key phenomenon in northern ecosystems, and it appears to be influenced by climate change. Reports of collapsing rodent cycles have attributed the changes to warmer winters, which weaken the interaction between voles and their specialist subnivean predators. Using population data collected throughout Finland during 1986–2011, we analyse the spatio-temporal variation in the interactions between populations of voles and specialist, generalist and avian predators, and investigate by simulations the roles of the different predators in the vole cycle. We test the hypothesis that vole population cyclicity is dependent on predator…

2019

(1) Background: The high-grade neuroepithelial tumor of the central nervous system with BCOR alteration (HGNET-BCOR) is a highly malignant tumor. Preclinical models and molecular targets are urgently required for this cancer. Previous data suggest a potential role of insulin-like growth factor (IGF) signaling in HGNET-BCOR. (2) Methods: The primary HGNET-BCOR cells PhKh1 were characterized by western blot, copy number variation, and methylation analysis and by electron microscopy. The expression of IGF2 and IGF1R was assessed by qRT-PCR. The effect of chemotherapeutics and IGF1R inhibitors on PhKh1 proliferation was tested. The phosphorylation of IGF1R and downstream molecules was assessed …