Search results for "zur"

showing 10 items of 321 documents

Pathogens and host immunity in the ancient human oral cavity.

2014

Calcified dental plaque (dental calculus) preserves for millennia and entraps biomolecules from all domains of life and viruses. We report the first high-resolution taxonomic and protein functional characterization of the ancient oral microbiome and demonstrate that the oral cavity has long served as a reservoir for bacteria implicated in both local and systemic disease. We characterize: (i) the ancient oral microbiome in a diseased state, (ii) 40 opportunistic pathogens, (iii) the first evidence of ancient human-associated putative antibiotic resistance genes, (iv) a genome reconstruction of the periodontal pathogen Tannerella forsythia, (v) 239 bacterial and 43 human proteins, allowing co…

ProteomeMolecular Sequence Data610 Medicine & health10071 Functional Genomics Center ZurichDental plaqueArticlePrehistòriaBacterial geneticsPeriodontal pathogenMicrobiology1311 GeneticsTandem Mass SpectrometryGermanyRNA Ribosomal 16SGeneticsmedicineTannerella forsythiaHumansDental CalculusMicrobiomePathogenPhylogenyMouthbiologyBase SequenceEcologyBacteroidetesMicrobiotaSequence Analysis DNAbiology.organism_classificationmedicine.diseaseRed complexHistory Medieval10182 Institute of Oral Biologystomatognathic diseasesArchaeology10076 Center for Integrative Human Physiology11294 Institute of Evolutionary Medicine570 Life sciences; biologyOral MicrobiomeFood AnalysisGenome BacterialNature genetics
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Reproducible and Consistent Quantification of the Saccharomyces cerevisiae Proteome by SWATH-mass spectrometry *

2015

Targeted mass spectrometry by selected reaction monitoring (S/MRM) has proven to be a suitable technique for the consistent and reproducible quantification of proteins across multiple biological samples and a wide dynamic range. This performance profile is an important prerequisite for systems biology and biomedical research. However, the method is limited to the measurements of a few hundred peptides per LC-MS analysis. Recently, we introduced SWATH-MS, a combination of data independent acquisition and targeted data analysis that vastly extends the number of peptides/proteins quantified per sample, while maintaining the favorable performance profile of S/MRM. Here we applied the SWATH-MS t…

ProteomicsOsmosisSaccharomyces cerevisiae Proteins1303 BiochemistryOsmotic shockSaccharomyces cerevisiae610 Medicine & health10071 Functional Genomics Center ZurichSaccharomyces cerevisiaeOsmosisMass spectrometryBiochemistryMass SpectrometryAnalytical Chemistry1312 Molecular BiologyData-independent acquisitionMolecular Biology1602 Analytical ChemistryChromatographybiologySelected reaction monitoringTechnological Innovation and ResourcesReproducibility of Resultsbiology.organism_classificationTargeted mass spectrometryProteomeCarbohydrate Metabolism570 Life sciences; biologyPeptidesMolecular & Cellular Proteomics
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La sépulture campaniforme d'enfant de la grotte Murée (Montagnac-Montpezat, Alpes-de-Haute-Provence)

2011

Provence-Alpes-Côte d'AzurMontagnac-MontpezatSépulture[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryCampaniformeEurope méditerranéennePréhistoireGrotte muréeChalcolithiqueArchéologie[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistoryrite funérairemobilier funéraireAlpes-de-Haute-ProvenceFranceenfantnouveau-né
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Un lieu de culte monumental gaulois dans le Mercantour : le site de la Cime de la Tournerie (commune de Roubion, Alpes-Maritimes)

2019

International audience; In the Southern Alps, the site of la Cime de La Tournerie, established on a mount peaking at an altitude of 1 816 m, is a monumental place of worship of the early second Iron Age. This site is caracterised by a network of concentric walls and ditches surronding a 500 m2 platform marked out by a monumental wall. Excavations conducted from 2014 to 2017 uncovered weapons, jewelry, remains of banquet, human bones, elements of monumental masonry and a Massaliot monetary storage of the third century BC.

Provence-Alpes-Côte d'Azur[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryDépartement des Alpes-MaritimesRoubion
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NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5-PHOSPHATE.

1964

Pyridoxal 5-PhosphateBrain chemistryCarboxy-LyasesBiochemistryCellular and Molecular Neurosciencechemistry.chemical_compoundNeurochemicalMesencephalonSeizuresCerebellumPonsIsoniazidPyridoxal phosphateTransaminasesBrain ChemistryPharmacologyMedulla OblongataGallamine TriethiodideChemistryAminobutyratesResearchBrainFrontal LobeElectrophysiologyBiochemistryPyridoxal PhosphateCatsJournal of neurochemistry
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The era of reference genomes in conservation genomics

2022

Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate reference genomes representing global biodiversity. These genomes provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses of population and functional genomics, and are expected to revolutionize conservation genomics.

QH301 Biology580 Plants (Botany)Genetics -- ResearchEvolutionsbiologibiodiversity conservation; conservation genetics; ERGA; European Reference Genome AtlasConservation genetics; Biodiversity conservation; European Reference Genome Atlas; ERGAAnimal genome mappingudc:630*1GenomeGEERGA[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDE.BE.BIOD]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.biodERGA ; Biodiversity [MeSH] ; Genomics [MeSH] ; Ecology Evolution Behavior and Systematics ; conservation genetics ; Genome [MeSH] ; biodiversity conservation ; European Reference Genome Atlas3rd-DASGenomicsBiodiversityreferenčni genomi[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM][SDE.BE.BEC]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.becChemistry10121 Department of Systematic and Evolutionary BotanygenomikaGE Environmental Sciences:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]biodiverzitetaSettore BIO/18 - GENETICAeducationQH426 GeneticsQH301European Reference Genome AtlasVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470[SDE.BE.EVO]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.evoGeneticsconservation genetics ; biodiversity conservation ; European Reference Genome Atlas ; ERGAgenomi10211 Zurich-Basel Plant Science CenterGenomesGenetikBiologyQH426Ecology Evolution Behavior and SystematicsEvolutionary BiologyBiodiversity conservation; Conservation genetics; European Reference Genome AtlasAmbientaleEcologíaGenética1105 Ecology Evolution Behavior and Systematicsconservation geneticsWildlife conservation570 Life sciences; biologyHuman medicinebiodiversity conservationAnimal genetics[SDE.BE]Environmental Sciences/Biodiversity and EcologyGenètica
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Determination of five pesticide residues in oranges by matrix solid-phase dispersion and liquid chromatography to estimate daily intake of consumers.

2001

Abstract Residues of benzoylphenylurea insecticides (diflubenzuron, hexaflumuron, and flufenuxuron), carboxamide acaricides (hexythiazox), and carbamate insecticides (benfuracarb) were determined in 150 orange fruit samples from September 1998 to June 1999, to estimate exposure of the Valencian population to oranges contaminated with these newly developed pesticides. The method for monitoring these residues is based on matrix solid-phase dispersion and liquid chromatography with UV or atmospheric pressure chemical ionization/mass spectrometry (APCI/MS) detection. Orange samples representing 11 varieties were collected from an agricultural cooperative and examined for the 5 pesticides. In 74…

Quality ControlCarbamateCitrusInsecticidesBenzoylphenylureamedicine.medical_treatmentPopulationFood ContaminationOrange (colour)Mass SpectrometryAnalytical Chemistrychemistry.chemical_compoundmedicineEnvironmental ChemistryeducationBenzofuransPharmacologyeducation.field_of_studyChromatographyPesticide residueChemistryAcaricidePhenylurea CompoundsPesticide ResiduesReproducibility of ResultsPesticideDiflubenzuronBenzamidesbeta-AlanineDiflubenzuronAgronomy and Crop ScienceFood ScienceChromatography LiquidJournal of AOAC International
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Matrix solid-phase dispersion microextraction and determination by high-performance liquid chromatography with UV detection of pesticide residues in …

1999

A multiresidue method based on matrix solid-phase dispersion (MSPD) microextraction was studied to determine the carbamate, benfuracarb, and urea insecticides, diflubenzuron, flufenoxuron hexaflumuron and hexythiazox, used in control of citrus pests. Optimisation of different parameters, such as the type of solid support for matrix dispersion, elution solvents and the clean-up step were carried out. The method used 0.5 g of orange sample, C8 bonded silica as MSPD sorbent and dichloromethane as eluting solvent. Recoveries, at spiked concentrations below the maximum residue levels established by Spanish Government, were between 74 and 84% with relative standard deviations ranging from 2 to 4%…

Quality ControlCarbamateInsecticidesmedicine.medical_treatmentBiochemistryHigh-performance liquid chromatographySensitivity and SpecificityAnalytical ChemistrymedicineSample preparationSolid phase extractionChromatography High Pressure LiquidBenzofuransChromatographyPesticide residueChemistryElutionPhenylurea CompoundsOrganic ChemistryPesticide ResiduesGeneral MedicineReversed-phase chromatographySolventFruitBenzamidesbeta-AlanineIndicators and ReagentsDiflubenzuronJournal of chromatography. A
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Photon Production from the Vacuum Close to the Superradiant Transition: Linking the Dynamical Casimir Effect to the Kibble-Zurek Mechanism

2012

The dynamical Casimir effect (DCE) predicts the generation of photons from the vacuum due to the parametric amplification of the quantum fluctuations of an electromagnetic field. The verification of such an effect is still elusive in optical systems due to the very demanding requirements of its experimental implementation. We show that an ensemble of two-level atoms collectively coupled to the electromagnetic field of a cavity, driven at low frequencies and close to a quantum phase transition, stimulates the production of photons from the vacuum. This paves the way to an effective simulation of the DCE through a mechanism that has recently found experimental demonstration. The spectral prop…

Quantum phase transitionKibble-Zurek mechanismElectromagnetic fieldPhysicsPhotonCavity quantum electrodynamicsGeneral Physics and AstronomyDynamical Casimir Effect Cold Atoms Cavity QEDRadiation01 natural sciencesSettore FIS/03 - Fisica Della Materia010305 fluids & plasmasCasimir effectQuantum mechanics0103 physical sciences010306 general physicsQuantum fluctuation
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Doege-Potter syndrome: When seizures and hypoglycemia collide.

2018

Reactive HypoglycemiaSeizuresInsulin-Like Growth FactorsElectroencephalographySolitary Fibrous Tumor of the PleuraLetter to EditorHypoglycemiaIranian journal of neurology
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