Search results for "zur"
showing 10 items of 321 documents
Brivaracetam as Early Add-On Treatment in Patients with Focal Seizures: A Retrospective, Multicenter, RealWorld Study
2022
Introduction: In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Most real-world research on BRV has focused on refractory epilepsy. The aim of this analysis was to assess the 12-month effectiveness and tolerability of adjunctive BRV when used as early or late adjunctive treatment in patients included in the BRIVAracetam add-on First Italian netwoRk Study (BRIVAFIRST). Methods: BRIVAFIRST was a 12-month retrospective, multicenter study including adult patients prescribed adjunctive BRV. Effectiveness outcomes included the rates of sustained seizure response, sustained seizure freedom, and treatment discontinua…
Vis/NIR spectroelectrochemical analysis of poly-(Azure A) on ITO electrode
2006
Electrochromic behavior of poly-(Azure A) on indium–tin oxide electrode is analyzed in an aqueous potassium nitrate solution. The dependence of the absorbance on the applied potential during cyclic voltammograms proves very interesting at two selected characteristic wavelengths: at 925 nm, attributed to an intermediate species and another at 735 nm, attributed to the oxidized form of the polymer. Molar absorptivity coefficients for both species have been calculated from the relationship between current and the derivative of absorbance with respect to time. Voltammograms of formation of the intermediate are simulated from spectroelectrochemical results. Keywords: Poly-(Azure A), Spectroelect…
Non-Invasive Investigation of Pigments of Wall Painting in S. Maria Delle Palate di Tusa (Messina, Italy)
2019
The characterization of materials used in the archaeological field needs an experimental approach in order to avoid the destruction or perturbation of artworks. In order to afford this purpose, a multi-analytical spectroscopic approach is regularly used. We combined non-invasive analysis by using handheld spectroscopic instrumentations (mainly XRF and Raman spectrometers) in order to characterize the wall painting preserved in the church of S. Maria delle Palate at Halaesa Arconidea archeological site (Tusa, Messina, Italy). The aim of the work is the characterization of the nature of pigments used for the realization of the wall painting. The wall painting, probably representing St. Franci…
Neurogenic pulmonary oedema after generalized epileptic seizure
1998
The diagnosis 'tonic clonic seizure' is frequently established by emergency physicians on scene. In patients with epilepsy mortality due to accidents, asphyxia, cardiac arrhythmias or postictal neurogenic pulmonary oedema (NPO) is twice as high as in the general population. We report a case of acute pulmonary oedema after a tonic clonic seizure. Following this event, the patient developed respiratory insufficiency and evidence of pulmonary oedema not associated with the classic aetiologies of congestive heart failure, aspiration or toxic exposure. The patient survived the incident after aggressive prehospital treatment, long-term intensive care and subsequent rehabilitation. A systematic ca…
Virtuālā aģenta izveide komunikācijas atbalstam
2020
Šī darba mērķis ir izpētīt virtuālos komunikācijas aģentus un izveidot savu virtuālo aģentu, lai risinātu reālu biznesa problēmu. Šī darba ietvaros ir izpētīta virtuālo aģentu būtība, kā arī to darba pamatprincips. Ir sastādīta virtuālo aģentu klasifikācija pēc dažādiem kritērijiem, ir izpētītas visizplatītākās platformas to veidošanai, kā arī ir izstrādāts savs virtuālais aģents priekš MS Teams ar Microsoft Bot Framework palīdzību. Darba pamattekstā ir 80 lappuses, 53 attēli, 5 tabulas un 30 informācijas avotu nosaukumi.
The clinical and molecular spectrum of QRICH1 associated neurodevelopmental disorder
2022
De novo variants in QRICH1 (Glutamine-rich protein 1) has recently been reported in 11 individuals with intellectual disability. The function of QRICH1 is largely unknown but it is likely to play a key role in the unfolded response of endoplasmic reticulum (ER) stress through transcriptional control of proteostasis. In this study, we present 27 additional individuals and delineate the clinical and molecular spectrum of the individuals (n=38) with QRICH1 variants. The main clinical features were mild to moderate developmental delay/intellectual disability (71%), non-specific facial dysmorphism (92%) and hypotonia (39%). Additional findings included poor weight gain (29%), short stature (29%)…
Family Matters : Abusing Family Refresh Tokens to Gain Unauthorised Access to Microsoft Cloud Services Exploratory Study of Azure Active Directory Fa…
2022
Azure Active Directory (Azure AD) is an identity and access management service used by Microsoft 365 and Azure services and thousands of third-party service providers. Azure AD uses OIDC and OAuth protocols for authentication and authorisation, respectively. OAuth authorisation involves four parties: client, resource owner, resource server, and authorisation server. The resource owner can access the resource server using the specific client after the authorisation server has authorised the access. The authorisation is presented using a cryptographically signed Access Token, which includes the identity of the resource owner, client, and resource. During the authorisation, Azure AD assigns Ac…
Exploring Azure Active Directory Attack Surface: Enumerating Authentication Methods with Open-Source Intelligence Tools
2022
Azure Active Directory (Azure AD) is Microsoft’s identity and access management service used globally by 90 per cent of Fortune 500 companies and many other organisations. Recent attacks by nation-state adversaries have targeted these organisations by exploiting known attack vectors. In this paper, open-source intelligence (OSINT) is gathered from organisations using Azure AD to explore the current attack surface. OSINT is collected from Fortune 500 companies and top 2000 universities globally. The collected OSINT includes authentication methods used by the organisation and the full name and phone number of the primary technical contact. The findings reveal that most organisations are using…
Pathogenic correlation between mosaic variegated aneuploidy 1 (MVA1) and a novel BUB1B variant: a reappraisal of a severe syndrome.
2022
Funder: Università degli Studi di Catania
Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort
2013
The work conducted at the WTCHG was supported by Wellcome Trust grants [076566/Z/05/Z] and [075491/Z/04]; the work in Zurich partly by an SNSF grant [32-108130]. We also thank MAF (Mutation Analysis core Facility) at the Karolinska Institute, Novum, Huddinge. The French part of the project was funded by Agence Nationale de la Recherche (ANR-06-NEURO-019-01 GENEDYS) and Ville de Paris. S Paracchini is a Royal Society University Research Fellow. D Czamara was supported by the Deutsche Forschungsgemeinschaft (German Research Foundation) within the framework of the Munich Cluster for Systems Neurology (EXC 1010 SyNergy). Dyslexia is one of the most common childhood disorders with a prevalence o…