Self-assembly of Clicked Star-Shaped Triazines into Functional Nanostructures

Two non‐amphiphilic star‐shaped 2,4,6‐tris(1,2,3‐triazol‐4‐yl)‐1,3,5‐triazines showing different behavior in terms of self‐assembly and luminescent properties are described. They aggregate in the liquid phase to form low‐dimensional nanostructures with a variety of morphologies, such as spherical particles, one‐hole hollow spheres, toroids, twisted fibers or helical nanotubes, just by varying the conditions of a straightforward reprecipitation method. Aggregation has an opposite effect concerning the fluorescent properties of the proposed compounds, either causing the enhancement or the quenching of the emission after the self‐assembly. Quantum chemical calculations have been also performed…

Cover Feature: Self-Assembly of Clicked Star-Shaped Triazines into Functional Nanostructures (ChemNanoMat 1/2019)

An update on the management and prevention of cytomegalovirus infection following allogeneic hematopoietic stem cell transplantation

ABSTRACT  A significant progress has been made in deciphering critical aspects of the biology and immunology of CMV infection in the allogeneic stem cell transplantation setting. Genetic traits predisposing to active CMV infection and CMV end-organ disease have begun to be delineated. Reliable molecular assays for CMV DNA load quantitation in body fluids have been developed. Elucidation of immune mechanisms affording control of CMV infection will help to improve the management of active CMV infection. Finally, the advent of new CMV-specific antivirals and promising vaccine prototypes as well as the development of fine procedures for large-scale ex vivo generation of functional CMV-specific…