0000000000008157

AUTHOR

Massimiliano Caprio

0000-0003-0722-7163

showing 11 related works from this author

Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive …

2021

Background: Ketogenic diet (KD) is a nutritional approach that restricts daily carbohydrates, replacing most of the reduced energy with fat, while maintaining an adequate quantity of protein. Despite the widespread use of KD in weight loss in athletes, there are still many concerns about its use in sports requiring muscle mass accrual. Thus, the present study sought to investigate the influence of a KD in competitive natural body builders. Methods: Nineteen volunteers (27.4 &plusmn

Blood GlucoseMalemedicine.medical_treatmentDiet Carbohydrate-Restricted0302 clinical medicineNeurotrophic factorsWeight lossInsulinTestosteroneHealth Ketogenic diet Resistance training StrengthInsulin-Like Growth Factor ITestosteroneNutrition and DieteticsMuscleshealthAdipose Tissueketogenic dietBody CompositionCytokinesmedicine.symptomDiet Ketogenicstrengthlcsh:Nutrition. Foods and food supplySettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieAdultmedicine.medical_specialtyAdolescentCarbohydrates030209 endocrinology & metabolismlcsh:TX341-641ArticleProinflammatory cytokineHealth; Ketogenic diet; Resistance training; Strength03 medical and health sciencesYoung AdultInternal medicineWeight LossmedicineHumansMuscle StrengthTriglyceridesbusiness.industryInsulinBrain-Derived Neurotrophic Factor030229 sport sciencesEndocrinologyGlucoseAthletesDiet WesternBasal metabolic rateLean body massBasal Metabolismresistance trainingbusinessFood ScienceKetogenic dietNutrients
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Effects of a ketogenic diet in overweight women with polycystic ovary syndrome.

2019

Abstract Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during reproductive age. It is characterised clinically by oligo-ovulation or anovulation, hyper-androgenism, and the presence of polycystic ovaries. It is associated with an increased prevalence of metabolic syndrome, cardiovascular disease and type 2 diabetes. The onset of PCOS has been associated to several hereditary and environmental factors, but insulin resistance plays a key pathogenetic role. We sought to investigate the effects of a ketogenic diet (KD) on women of childbearing age with a diagnosis of PCOS. Methods Fourteen overweight women with diagnosis of PCOS underwent to a ketoge…

0301 basic medicinemedicine.medical_specialtyLow carbohydrate dietlcsh:Medicine030209 endocrinology & metabolismType 2 diabetesGeneral Biochemistry Genetics and Molecular BiologyBody Mass IndexAnovulation03 medical and health sciencesFollicle-stimulating hormoneHyperinsulinemia0302 clinical medicineSex hormone-binding globulinInsulin resistanceInternal medicinemedicinePCOSHumansInsulin030109 nutrition & dieteticsbiologybusiness.industryHyperinsulinemia Ketogenic diet Ketone bodies LCKD Low carbohydrate diet Overweight PCOSResearchlcsh:Rnutritional and metabolic diseasesGeneral MedicineLuteinizing HormoneOverweightKetogenic dietmedicine.diseaseLCKDPolycystic ovaryEndocrinologyDiabetes Mellitus Type 2Hyperinsulinemia; Ketogenic diet; Ketone bodies; LCKD; Low carbohydrate diet; Overweight; PCOSbiology.proteinLean body massKetone bodiesFemaleMetabolic syndromeInsulin ResistancebusinessDiet KetogenicSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotoriePolycystic Ovary SyndromeJournal of translational medicine
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Losing weight after menopause with minimal aerobic training and mediterranean diet

2020

Objective: It is a common belief that menopausal women have greater difficulty losing weight. The aim of this study was to assess the efficacy of a Mediterranean diet (MD) to promote weight loss in postmenopausal women. All participants were prescribed a hypocaloric traditional MD, tailored to the individual. Subjects were asked not to begin any kind of physical activity. Body composition was measured at the beginning and after 8 weeks of treatment. In total, 89 women (age 52.8 &plusmn

Weight lossMediterranean dietPhysiology030209 endocrinology & metabolismlcsh:TX341-641Diet MediterraneanPlant Proteins DietarySettore MED/49Body compositionArticle03 medical and health sciences0302 clinical medicineSettore MED/13Weight lossMediterranean dietAnimal Proteins DietaryMass variationHumansMedicineAerobic exerciseNutritional Physiological Phenomena030212 general & internal medicineExerciseNutrition and Dieteticsbusiness.industryMetabolic riskAge FactorsMiddle AgedChronic degenerative diseasesmedicine.diseaseLipoproteins LDLWeight Reduction ProgramsMenopauseBlood pressureAdipose TissueHeart Disease Risk FactorsFemalemedicine.symptomMenopausebusinesslcsh:Nutrition. Foods and food supplyFood ScienceLipoprotein
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Effects of quality and quantity of protein intake for type 2 Diabetes Mellitus prevention and metabolic control

2020

Purpose of Review: The aim of this review is to evaluate the ideal protein quality and quantity and the dietary composition for the prevention and metabolic control of type 2 diabetes mellitus (T2DM). Introduction: Although some reviews demonstrate the advantages of a diet with a higher protein intake, other reviews have observed that a diet high in carbohydrates, with low-glycaemic index carbohydrates and good fibre intake, is equally effective in improving insulin sensitivity. Methods: Over 2831 articles were screened, and 24 from the last 5 years were analysed and summarised for this review, using the protein, diabetes and insulin glucose metabolic keywords in Pubmed in June 2019. Result…

0301 basic medicineDietary FiberMeatDatabases Factualmedicine.medical_treatmentPhysiology030209 endocrinology & metabolismType 2 diabetesDiet; Intake; Protein; Quality; Type 2 diabetesSettore MED/4903 medical and health sciencesEating0302 clinical medicineSettore MED/13Diabetes mellitusmedicineAnimalsHumansMetabolic Syndrome030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryInsulinProteinType 2 Diabetes MellitusProteinsType 2 diabetesmedicine.diseaseQualityDietDiabetes Mellitus Type 2Plant proteinGlycemic IndexMetabolic control analysisIntakeDairy ProductsMetabolic syndromeInsulin ResistancebusinessProtein qualityFood Science
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Diet Rich in Plant Protein May Prevent Type 2 Diabetes

2020

Purpose : The aim is to show the ideal protein quality and quantity and the dietary composition for the prevention and metabolic control of type 2 diabetes mellitus (T2DM). Introduction Although some reviews demonstrate the advantages of a diet with a higher protein intake, other reviews have observed that a diet high in carbohydrates, with low-glycaemic index carbohydrates and good fibre intake, is equally effective in improving insulin sensitivity. Methods Over 2831 articles were screened, and 24 from the last 5 years were analysed and summarised for this review, using the protein, diabetes and insulin glucose metabolic keywords in Pubmed in June 2019. Results Eleven studies demonstrate t…

business.industryInsulinmedicine.medical_treatmentType 2 Diabetes MellitusType 2 diabetesmedicine.diseasePlant proteinMetabolic control analysisDiabetes mellitusmedicineFood scienceMetabolic syndromebusinessProtein qualityProceedings of The 1st International Electronic Conference on Plant Science
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The different daily distribution of proteins does not influence the variations in body composition in a sample of subjects undergoing a low-calorie m…

2021

BACKGROUND Controversy exists regarding whether the different daily balances of proteins between meals and snacks in a low-calorie diet may influence the effects on body composition (BC) results. Aim of this study is to evaluate BC changes made by a lifestyle intervention in a randomized homogeneous sample of two groups with equal daily caloric reduction but different protein distributions between meals. METHODS Forty-seven men and women (mean age: 32±10 years; Body Mass Index: 28.4±2.4 kg/m2) consumed an energy-restricted diet (788 kcal/d below the requirement) for eight weeks in a free-living contest. Subjects consumed 90.1 g protein/d (1.10±0.16 g/kg/day) and were randomized in an EVEN (…

AdultMaleWeight lossEndocrinology Diabetes and MetabolismOverweightBody compositionSettore MED/49Young AdultAnimal scienceSettore MED/13Weight reduction programsLifestyle interventionInternal MedicineHumansMedicineMealsCaloric RestrictionReducing dietbusiness.industrydigestive oral and skin physiologyGastroenterologyProteinsLow calorieMean ageDietDistribution patternLean body massFemaleComposition (visual arts)medicine.symptomEnergy IntakebusinessBody mass index
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High plant-based diet and physical activity in women during menopausal transition

2021

Purpose The menopausal transition (MT) is a period when there may be an increase in visceral fat mass and a worsening of cardiometabolic risk factors. Few studies have evaluated the efficacy of plant-based low-calorie diets on groups of women at different stages of MT. The purpose of this study is to compare the effectiveness of a high plant-to-animal protein ratio diet in women of similar age but with different fertility statuses. Design/methodology/approach Subjects were divided into three groups according to their fertility status at the baseline: “premenopausal” (n = 11), “perimenopause” (n = 14) and “postmenopause” (n = 18). Body composition (BC) was measured at the beginning and afte…

Weight lossNutrition and DieteticsPhysical activitybusiness.industryPhysical activityPhysiologyPlant basedmedicine.diseaseBody compositionPlant-based dietMenopauseWeight lossmedicineMenopausemedicine.symptombusinessFood ScienceNutrition & Food Science
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Exploring the Role of Skeletal Muscle in Insulin Resistance: Lessons from Cultured Cells to Animal Models

2021

Skeletal muscle is essential to maintain vital functions such as movement, breathing, and thermogenesis, and it is now recognized as an endocrine organ. Muscles release factors named myokines, which can regulate several physiological processes. Moreover, skeletal muscle is particularly important in maintaining body homeostasis, since it is responsible for more than 75% of all insulin-mediated glucose disposal. Alterations of skeletal muscle differentiation and function, with subsequent dysfunctional expression and secretion of myokines, play a key role in the pathogenesis of obesity, type 2 diabetes, and other metabolic diseases, finally leading to cardiometabolic complications. Hence, a de…

QH301-705.5glucose metabolismAdipose tissueReviewType 2 diabetesCarbohydrate metabolismMuscle DevelopmentBioinformaticsCatalysisInorganic ChemistryInsulin resistanceMyokineAnimalsHumansMedicinePhysical and Theoretical ChemistryBiology (General)Muscle SkeletalMolecular BiologyQD1-999Spectroscopybusiness.industryOrganic ChemistrySkeletal musclefree fatty acidsGeneral Medicinemedicine.diseaseComputer Science Applicationsadipose tissueglycemiaDisease Models AnimalChemistrymedicine.anatomical_structureDiabetes Mellitus Type 2Adipose tissue Free fatty acids Glucose metabolism Glycemia Myofibers Animals Diabetes Mellitus Type 2 Humans Muscle Skeletal Disease Models Animal Insulin Resistance Muscle DevelopmentInsulin ResistancebusinessThermogenesismyofibersHomeostasisInternational Journal of Molecular Sciences
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Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome

2022

Metabolic Syndrome (MetS) is a cluster of metabolic alterations mostly related to visceral adiposity, which in turn promotes glucose intolerance and a chronic systemic inflammatory state, characterized by immune cell infiltration. Such immune system activation increases the risk of severe disease subsequent to viral infections. Strong correlations between elevated body mass index (BMI), type-2-diabetes and increased risk of hospitalization after pandemic influenza H1N1 infection have been described. Similarly, a correlation between elevated blood glucose level and SARS-CoV-2 infection severity and mortality has been described, indicating MetS as an important predictor of clinical outcomes i…

InflammationMetabolic SyndromeobesityNutrition and DieteticsadipokineSARS-CoV-2agingmyokinesImmunityphysical activityCOVID-19Nutritional Statusmyokineadipose tissuenutritionSettore MED/13Influenza A Virus H1N1 SubtypeInfluenza A VirusHumansH1N1 Subtypeskeletal muscleadipokinesExerciseimmune functionFood ScienceNutrients
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Liraglutide improves metabolic parameters and carotid intima-media thickness in diabetic patients with the metabolic syndrome: an 18-month prospectiv…

2016

Abstract Background Liraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers. However, the effects of liraglutide on cardiovascular (CV) risk markers in subjects with the metabolic syndrome (MetS) are still largely unknown. We herein explored its effects on various cardio-metabolic risk markers of the MetS in subjects with T2DM. Methods We performed an 18-month prospective, real-world study. All subjects had T2DM and the MetS based on the AHA/NHLBI criteria. Subjects with a history of a major CV event were excluded. One hundred-twenty-one subject…

Carotid Artery DiseasesMaleEndocrinology Diabetes and MetabolismPredictive Value of Test030204 cardiovascular system & hematologyCarotid intima-media thickne0302 clinical medicineRisk FactorsPrevalenceProspective StudiesCarotid intima-media thicknessProspective cohort studyOriginal Investigation2. Zero hungerIncretinMiddle AgedMetabolic syndromeMetformin3. Good healthMetforminTreatment OutcomeItalyCardiologyDrug Therapy CombinationFemaleCardiology and Cardiovascular MedicineHumanmedicine.drugmedicine.medical_specialtyIncretin030209 endocrinology & metabolismIncretins03 medical and health sciencesPredictive Value of TestsInternal medicineDiabetes mellitusmedicineHumansHypoglycemic AgentsCardiovascular risk Carotid intima-media thickness Liraglutide Metabolic syndromeAgedCarotid Artery DiseaseHypoglycemic AgentLiraglutidebusiness.industryRisk FactorBiomarkerLiraglutideCardiovascular riskmedicine.diseaseEchocardiography Doppler ColorProspective StudieDiabetes Mellitus Type 2Intima-media thicknessMetabolic syndromebusinessBody mass indexBiomarkersCardiovascular Diabetology
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Effect of 30 days of ketogenic Mediterranean diet with phytoextracts on athletes' gut microbiome composition.

2022

BackgroundRecent research suggest that gut microbiome may play a fundamental role in athlete's health and performance. Interestingly, nutrition can affect athletic performance by influencing the gut microbiome composition. Among different dietary patterns, ketogenic diet represents an efficient nutritional approach to get adequate body composition in athletes, however, some concerns have been raised about its potential detrimental effect on gut microbiome. To the best of our knowledge, only one study investigated the effect of ketogenic diet on the gut microbiome in athletes (elite race walkers), whilst no studies are available in a model of mixed endurance/power sport such as soccer. This …

athletes; exercise; gut microbiota; ketogenic diet; sport nutritionNutrition and Dieteticsathletesexercisegut microbiotaketogenic dietEndocrinology Diabetes and Metabolismsport nutritionFood ScienceFrontiers in nutrition
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