0000000000014826

AUTHOR

David E. Laaksonen

showing 12 related works from this author

Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children

2018

BACKGROUND There are few prospective studies on the associations of changes in objectively measured vigorous physical activity (VPA∆ ), moderate-to-vigorous physical activity (MVPA∆ ), light physical activity (LPA∆ ), and sedentary time (ST∆ ) with changes in cardiometabolic risk factors (∆ ) in children. We therefore investigated these relationships among children. METHODS The participants were a population sample of 258 children aged 6-8 years followed for 2 years. We assessed PA and ST by a combined heart rate and movement sensor; computed continuous age- and sex-adjusted z-scores for waist circumference, blood pressure, and fasting insulin, glucose, triglycerides, and high-density lipop…

Blood GlucoseMaleCross-sectional studyphysical activityBlood Pressureliikunta030204 cardiovascular system & hematologyBody fat percentagechemistry.chemical_compound0302 clinical medicineHeart RateRisk FactorsInsulinOrthopedics and Sports MedicineLongitudinal StudiesProspective StudiesChildta315Prospective cohort studyFinlandAnthropometryriskitekijätLipidsCardiovascular DiseasesFemalelipids (amino acids peptides and proteins)Waist Circumferencefyysinen aktiivisuusmedicine.medical_specialtyWaistPhysical Therapy Sports Therapy and Rehabilitationpitkittäistutkimusta3111Article03 medical and health sciencesMetabolic DiseaseschildrenInternal medicineHeart ratemedicineHumansExerciselapsetCholesterolbusiness.industryterveydentila030229 sport sciencesAnthropometrycardiometabolic risk factorsCross-Sectional StudiesBlood pressurechemistrySedentary BehaviorbusinessScandinavian Journal of Medicine & Science in Sports
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Heart Rate Dynamics after Combined Strength and Endurance Training in Middle-Aged Women: Heterogeneity of Responses

2013

The loss of complexity in physiological systems may be a dynamical biomarker of aging and disease. In this study the effects of combined strength and endurance training compared with those of endurance training or strength training alone on heart rate (HR) complexity and traditional HR variability indices were examined in middle-aged women. 90 previously untrained female volunteers between the age of 40 and 65 years completed a 21 week progressive training period of either strength training, endurance training or their combination, or served as controls. Continuous HR time series were obtained during supine rest and submaximal steady state exercise. The complexity of HR dynamics was assesse…

Adultsykemedicine.medical_specialtyAnatomy and PhysiologyTime FactorsSupine positionStrength trainingeducationPhysical fitnesslcsh:Medicine030204 cardiovascular system & hematologyBiologyCardiovascularCardiovascular Systemlaw.invention03 medical and health sciencesEngineering0302 clinical medicineRandomized controlled trialHeart RatelawEndurance trainingHeart rateheart ratemedicineStatistical Signal ProcessingHumansSports and Exercise Medicinelcsh:ScienceBiologyAgedTraining periodRelated factorsMultidisciplinarybusiness.industrylcsh:RResistance Training030229 sport sciencesMiddle AgedSignal ProcessingCirculatory PhysiologyPhysical EndurancePhysical therapyMedicinelcsh:QFemalebusinessResearch ArticlePLoS ONE
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A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC stud…

2020

Abstract Aims/hypothesis We studied for the first time the long-term effects of a combined physical activity and dietary intervention on insulin resistance and fasting plasma glucose in a general population of predominantly normal-weight children. Methods We carried out a 2 year non-randomised controlled trial in a population sample of 504 children aged 6–9 years at baseline. The children were allocated to a combined physical activity and dietary intervention group (306 children at baseline, 261 children at 2-year follow-up) or a control group (198 children, 177 children) without blinding. We measured fasting insulin and fasting glucose, calculated HOMA-IR, assessed physical activity and se…

Blood GlucoseMaleEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPhysiologyphysical activitylean body massruokavaliotBody fat percentageHOMA-IRlaw.inventionBody Mass Indexglukoosi0302 clinical medicineRandomized controlled triallawInsulinBody Size030212 general & internal medicineglucoseChildChildreninterventioneducation.field_of_studyBody movementinterventiotutkimusFastingSedentary timebody fatLean body massBody fatBody CompositionFemalefyysinen aktiivisuusinsulinPopulationsedentary time030209 endocrinology & metabolismlapset (ikäryhmät)InterventioninsuliiniArticle03 medical and health sciencesInsulin resistancechildrenHeart rateInternal MedicinemedicineHumanseducationExercisekehonkoostumusbusiness.industryPhysical activityInsulinmedicine.diseaseDietGlucoseLean body massInsulin Resistancebusinessdiet
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Dietary fiber and the glycemic index: a background paper for the Nordic Nutrition Recommendations 2012

2013

The aim of this study is to review recent data on dietary fiber (DF) and the glycemic index (GI), with special focus on studies from the Nordic countries regarding cardiometabolic risk factors, type 2 diabetes, cardiovascular disease, cancer, and total mortality. In this study, recent guidelines and scientific background papers or updates on older reports on DF and GI published between 2000 and 2011 from the US, EU, WHO, and the World Cancer Research Fund were reviewed, as well as prospective cohort and intervention studies carried out in the Nordic countries. All of the reports support the role for fiber-rich foods and DF as an important part of a healthy diet. All of the five identified N…

0301 basic medicineGerontologyPopulation030209 endocrinology & metabolismlcsh:TX341-641DiseaseType 2 diabetesReview ArticleOverweightLower riskVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 81103 medical and health sciences0302 clinical medicineBreast cancermedicinedietary fiber; glycemic index; Nordic Nutrition RecommendationseducationProspective cohort studyeducation.field_of_study030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryPublic Health Environmental and Occupational HealthNordic Nutrition Recommendationsmedicine.diseasedietary fiberGlycemic indexpopulation characteristicsglycemic indexmedicine.symptombusinesslcsh:Nutrition. Foods and food supplyFood ScienceFood & Nutrition Research
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The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study

2020

Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126

Very low-density lipoproteinphysical activityMedicine (miscellaneous)030204 cardiovascular system & hematologyruokavaliot0302 clinical medicine030212 general & internal medicineChildChildreninterventioneducation.field_of_studyNutrition and DieteticsinterventiotutkimusOriginal ContributionLDL cholesterolmedicine.symptomfyysinen aktiivisuuselintavatmedicine.medical_specialtylipoproteiinitLipoproteinsPopulationPhysical activitylapset (ikäryhmät)Intervention03 medical and health scienceschildrenInternal medicineIntervention (counseling)Heart ratePlasma lipidsmedicineHumansLDL-kolesterolieducationExerciseTriglyceridesLdl cholesterolPhysical activitybusiness.industryCholesterol HDLPanicCholesterol LDLDietary FatsDietlipoproteinsEndocrinologysense organsSedentary BehaviordietbusinessEuropean Journal of Nutrition
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Does high sugar consumption exacerbate cardiometabolic risk factors and increase the risk of type 2 diabetes and cardiovascular disease?

2012

Consumption of sugar has been relatively high in the Nordic countries; the impact of sugar intake onmetabolic risk factors and related diseases has been debated. The objectives were to assess the effect of sugarintake (sugar-sweetened beverages, sucrose and fructose) on association with type 2 diabetes, cardiovasculardisease and related metabolic risk factors (impaired glucose tolerance, insulin sensitivity, dyslipidemia, bloodpressure, uric acid, inflammation markers), and on all-cause mortality, through a systematic review ofprospective cohort studies and randomised controlled intervention studies published between January 2000and search dates. The methods adopted were as follows: the fir…

0301 basic medicinemedicine.medical_specialtylcsh:TX341-641030209 endocrinology & metabolismType 2 diabetesDiseaseReview ArticleVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811fructoseImpaired glucose tolerance03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNordic nutrition recommendationssystematic reviewInternal medicinemedicineProspective cohort study030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryPublic Health Environmental and Occupational Healthmedicine.diseaseBlood pressurechemistrysugarUric acidbusinesssugar-sweetened beverageslcsh:Nutrition. Foods and food supplyDyslipidemiaFood ScienceCohort studyFoodnutrition research
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Associations of Physical Activity and Sedentary Behavior with Academic Skills – A Follow-Up Study among Primary School Children

2014

Background There are no prospective studies that would have compared the relationships of different types of physical activity (PA) and sedentary behavior (SB) with academic skills among children. We therefore investigated the associations of different types of PA and SB with reading and arithmetic skills in a follow-up study among children. Methods The participants were 186 children (107 boys, 79 girls, 6–8 yr) who were followed-up in Grades 1–3. PA and SB were assessed using a questionnaire in Grade 1. Reading fluency, reading comprehension and arithmetic skills were assessed using standardized tests at the end of Grades 1–3. Results Among all children more recess PA and more time spent i…

MaleParentsEpidemiologySocial Scienceslcsh:Medicinephysical activityDevelopmental and Pediatric NeurologyPediatricsDevelopmental psychologyChild DevelopmentCognitionSurveys and QuestionnairesReading (process)Medicine and Health SciencesPsychologyPublic and Occupational Healthta516Pediatric EpidemiologyChildlcsh:Scienceta315Finlandta515media_commonSchoolsMultidisciplinaryChild HealthFollow up studiesta3142Sedentary behaviorNeurologyEducational StatusFemaleBehavioral and Social Aspects of HealthComprehensionPsychologyResearch Articlemedia_common.quotation_subjecteducationPhysical activityStandardized testMotor ActivityFluencychildrenMental Health and PsychiatryHumansSports and Exercise MedicineStudentsBehaviorbusiness.industrylcsh:RBiology and Life SciencesReadingacademic skillsAcademic skillsReading comprehensionDevelopmental Psychologylcsh:QSedentary BehaviorbusinessMathematicsPLoS ONE
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Effects of strength and endurance training on metabolic risk factors in healthy 40–65-year-old men

2009

This study compared 21 weeks of combined high-intensity strength and endurance training with endurance or strength training only on metabolic risk factors in 40-65-year-old men. The healthy men (n=63) were randomized into endurance (E), strength (S), combined strength and endurance training (SE) and control (C) groups. S and E trained two times a week and SE 2+2 times a week. Systolic (SBP) and diastolic blood pressure decreased significantly both in E (-6+/-8 and -4+/-6 mmHg) and in S (-9+/-8 and -5+/-7 mmHg), but not in SE or C (P=0.003 for the difference in the changes of SBP between the groups). The changes in serum glucose and insulin during an oral glucose tolerance test did not diffe…

AdultMalemedicine.medical_specialtyStrength trainingLipoproteinsPhysical fitnessBlood lipidsBlood PressurePhysical Therapy Sports Therapy and RehabilitationOxygen ConsumptionRisk FactorsEndurance trainingInternal medicineHumansInsulinMedicineOrthopedics and Sports MedicineFinlandAgedAnthropometrybusiness.industryVO2 maxResistance TrainingCardiorespiratory fitnessMiddle Agedmedicine.diseaseGlucoseBlood pressureEndocrinologyExercise TestPhysical EnduranceMetabolic syndromeEnergy MetabolismbusinessScandinavian Journal of Medicine & Science in Sports
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Serum basal hormone concentrations, nutrition and physical fitness during strength and/or endurance training in 39-64-year-old women.

2009

We examined effects of 21 weeks of strength and/or endurance training and nutrition on serum hormones and physical fitness in 39-64-year-old women. Subjects (n=79) were randomized into the endurance group (E), strength group (S), combined group (SE) and controls (C). Total body strength training and high-intensity bicycle training were used. Average energy and nutrient intake remained the same in all groups. Body fat (dual energy X-ray absorptiometry) decreased significantly in all training groups and body mass index in E, SE and C. Only SE increased total body lean mass (2.2%, p=0.001), between groups p=0.044. Maximal cycling power increased more in E (16%) and SE (17%) than in S (8%)(all …

Adultmedicine.medical_specialtyStrength trainingPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationBody Mass IndexBasal (phylogenetics)EatingEndurance trainingInternal medicinemedicineHumansOrthopedics and Sports MedicineKneeInsulin-Like Growth Factor ISerum hormonesbusiness.industryResistance TrainingMiddle AgedAdaptation PhysiologicalHormonesEndocrinologyPhysical FitnessLean body massPhysical EnduranceFemalebusinessBody mass indexHormoneInternational journal of sports medicine
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Heart Rate Dynamics after Combined Endurance and Strength Training in Older Men

2009

Purpose: Aging alters cardiac autonomic function, which may contribute to a higher risk of cardiac events. Spectral measures of HR variability (HRV) and fractal-like behavior of HR are considered as markers of a healthy heart. The present study examined the effects of combining endurance and strength training compared with endurance or strength training alone on HR dynamics and physical fitness in older previously untrained men aged 40-67 yr. Methods: Subjects were randomized into endurance training (E, n = 23), strength training (S, n = 25), combined endurance and strength training (ES, n = 29), or control group (C, n = 16). Short-term fractal scaling exponent ([alpha]1) and spectral HRV w…

MaleAgingmedicine.medical_specialtyTime FactorsErgometryStrength trainingPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationPhysical exerciseAutonomic Nervous SystemOxygen ConsumptionHeart RateRisk FactorsEndurance trainingIsometric ContractionOne-repetition maximumInternal medicineHeart ratemedicineHumansOrthopedics and Sports MedicineMuscle StrengthMuscle SkeletalExerciseAerobic capacityAgedAnalysis of Variancebusiness.industryAge FactorsVO2 maxMiddle AgedPhysical EnduranceCardiologyPhysical therapybusinessMedicine & Science in Sports & Exercise
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Body Composition and Fitness during Strength and/or Endurance Training in Older Men

2008

PURPOSE: This study examined adaptations in body composition and physical fitness during a 21-wk strength and/or endurance training period in 40- to 65-yr-old men. We also compared the usefulness of different methods for the analysis of body composition to detect training-induced adaptations. METHODS: Fifty-three men were randomized into the endurance training (E: N = 14), strength training (S: N = 13), combined strength and endurance training (SE: N = 15), or control (C: N = 11) groups. S and E trained 2 and SE 2 x 2 times a week for strength and endurance. RESULTS: Percentage of fat (fat%) decreased (5-8%) similarly in all training groups. Fat% measured by DXA at baseline and its change c…

AdultMalemedicine.medical_specialtyWaistStrength trainingPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationAbsorptiometry PhotonOxygen ConsumptionAnimal scienceEndurance trainingElectric ImpedanceHumansMedicineOrthopedics and Sports MedicineAgedAnalysis of VariancePhysical Education and Trainingbusiness.industryReproducibility of ResultsVO2 maxMiddle AgedAdaptation PhysiologicalWaistlinePhysical FitnessBody CompositionExercise TestPhysical EndurancePhysical therapyLean body massAnalysis of variancebusinessMedicine & Science in Sports & Exercise
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Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in child…

2016

Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited. Objective: We investigated the effects of a dietary and physical activity intervention on plasma fatty acid composition of cholesteryl esters (CEs) and phospholipids and estimated desaturase and elongase activities in children. Design: We conducted a 2-y controlled dietary and physical activity intervention based on Finnish nutrition and physical activity recommendations in a population sample of 506 children aged 6–8 y. We assessed plasma fatty acid composition by gas chromatography and estimated desaturase and elongase activities as the ratio of product fatty acids to pr…

Fatty Acid DesaturasesMaleHealth BehaviorMedicine (miscellaneous)physical activity030204 cardiovascular system & hematologychemistry.chemical_compound0302 clinical medicineFood scienceChildta315FinlandPhospholipidsinterventionchemistry.chemical_classificationNutrition and Dieteticsalpha-Linolenic Acidta3141elongaseLipidsTreatment OutcomeBiochemistrycholesteryl esterFatty Acids UnsaturatedCholesteryl esterFemaleCholesterol EstersStearic acidPolyunsaturated fatty acidFatty Acid ElongasesLinoleic acidPhysical activityPhospholipidGuidelines as Topic030209 endocrinology & metabolismHealth Promotionta3111Linoleic Acid03 medical and health scienceschildrenAcetyltransferasesHumansExerciseLife StylephospholipidFatty acidOleic acidchemistryfatty aciddietdesaturaseAmerican Journal of Clinical Nutrition
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