0000000000020680
AUTHOR
David Brown
showing 13 related works from this author
Reflexive Modernization and the Disembedding of Jūdō from 1946 to the 2000 Sydney Olympics
2004
This article considers some of the sociologically significant changes to jūdō in its process of transformation from a Budō based martial art into a modern competitive spectator sport. Taking the period of time from 1946 until the Sydney Olympics, an examination is undertaken using Giddens’s notion of reflexive modernization in which key aspects of the original jūdō are disembedded or ‘lifted out’ of the practice. They are then re-embedded with western structures, practices and meanings. Central themes to emerge from this analysis are the social forces of internationalization, institutionalization and commodification of jūdō over this period, each of which contributes to a reflexive moderni…
Rationale and design of the EMBRACE STEMI Study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability …
2012
Background Although significant efforts have been made to improve ST-segment elevation myocardial infarction (STEMI) outcomes by reducing symptom-onset-to-reperfusion times, strategies to decrease the clinical impact of ischemic reperfusion injury have demonstrated limited success. Bendavia, an intravenously administered mitochondrial targeting peptide, has been shown to reduce myocardial infarct size and attenuate coronary no-reflow in experimental modelswhen given before reperfusion. Design The EMBRACE STEMI study is a phase 2a, randomized, double-blind, placebo-controlled trial enrolling 300 patients with a first-time anterior STEMI and an occluded proximal or mid–left anterior descendin…
Old World Megadroughts and Pluvials During the Common Era
2015
An atlas of megadroughts in Europe and in the Mediterranean Basin during the Common Era provides insights into climate variability.
Studien zum Vorgang der Wasserstoffübertragung, 41. Elektroreduktion von Acetophenon unter Mitwirkung optisch aktiver Leitsalze
1977
Die Anderung des Carbinol/Pinakol-Verhaltnisses2) (C/P) und der optischen Induktion bei der Elektroreduktion von Acetophenon mit (1 R, 2S)-N-(3-Cyanpropyl)-N-methylephedriniumbromid (1) und (1 R, 2 S)-N,N-Dimethylephedriniumbromid (2) als Leitsalze wird untersucht in Abhangigkeit: a) vom Potential (Tabelle 1), b) von der Stromdichte (Tabelle 2), c) von Pulsbedingungen (Tabelle 3), d) vom pH (Tabelle 4), e) von der Anwesenheit anderer Kationen (Tabelle 5), f) vom Losungsmittel (Tabelle 6), g) von der Temperatur (Tabelle 7) und h) von der Art des Elektrodenmaterials (Tabelle 8). — Es werden tensammetrische und cyclovoltammetrische Messungen durchgefuhrt. Die in trockenem Dimethylformamid erha…
Evidence for Simultaneous Production ofJ/ψandϒMesons
2016
We report evidence for the simultaneous production of $J/\psi$ and $\Upsilon$ mesons in 8.1 fb$^{-1}$ of data collected at $\sqrt{s}=$1.96 TeV by the D0 experiment at the Fermilab $p \bar p$ Tevatron Collider. Events with these characteristics are expected to be produced predominantly by gluon-gluon interactions. In this analysis, we extract the effective cross section characterizing the initial parton spatial distribution, $\sigma_{eff}=2.2\pm 0.7\mbox{(stat)} \pm 0.9 \mbox{(syst)} ~\mbox{mb}$.
Acetylcholine receptors (muscarinic) in GtoPdb v.2021.3
2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in the human body and are therefore attractive targets for many disorders. Functionally, M1, M3, and M5 mAChRs preferentially couple to Gq/11 proteins, whilst M2 and M4 mAChRs predominantly couple to Gi/o proteins. Both agonists and antagonists of mAChRs are clinically approved drugs, including pilocarpine for the treatment of elevated intra-ocular pressure and glaucoma, and atropine for the treatment of bradycardia and poisoning by muscarinic age…
Acetylcholine receptors (muscarinic) in GtoPdb v.2021.2
2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in the human body and are therefore attractive targets for many disorders. Functionally, M1, M3, and M5 mAChRs preferentially couple to Gq/11 proteins, whilst M2 and M4 mAChRs predominantly couple to Gi/o proteins. Both agonists and antagonists of mAChRs are clinically approved drugs, including pilocarpine for the treatment of elevated intra-ocular pressure and glaucoma, and atropine for the treatment of bradycardia and poisoning by muscarinic age…
FIDO science payload simulating the Athena Payload
2002
[1] The Jet Propulsion Laboratory's Field Integrated Development and Operations rover (FIDO) emulates and tests operational rover capabilities for advanced Mars rover missions, such as those originally planned for the Mars Surveyor 2001 Rover and currently planned for the Athena Payload on the Mars Exploration Rovers scheduled for launch in 2003. This paper describes FIDO's science instrument payload, which is fully integrated with rover hardware and software. Remote science teams visualize instrument suite data and generate FIDO commands using the Web Interface for Telescience. FIDO's instrument suite has been used in terrestrial laboratory and field tests to simulate Mars operations, to t…
Acetylcholine receptors (muscarinic) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
2019
Muscarinic acetylcholine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [45]) are GPCRs of the Class A, rhodopsin-like family where the endogenous agonist is acetylcholine. In addition to the agents listed in the table, AC-42, its structural analogues AC-260584 and 77-LH-28-1, N-desmethylclozapine, TBPB and LuAE51090 have been described as functionally selective agonists of the M1 receptor subtype via binding in a mode distinct from that utilized by non-selective agonists [243, 242, 253, 155, 154, 181, 137, 11, 230]. There are two pharmacologically characterised allosteric sites on muscarinic receptors, one defined by it binding gallami…
Odderon Exchange from Elastic Scattering Differences between pp and pp¯ Data at 1.96 TeV and from pp Forward Scattering Measurements
2021
We describe an analysis comparing the p p ¯ elastic cross section as measured by the D0 Collaboration at a center-of-mass energy of 1.96 TeV to that in p p collisions as measured by the TOTEM Collaboration at 2.76, 7, 8, and 13 TeV using a model-independent approach. The TOTEM cross sections, extrapolated to a center-of-mass energy of s = 1.96 TeV , are compared with the D0 measurement in the region of the diffractive minimum and the second maximum of the p p cross section. The two data sets disagree at the 3.4 σ level and thus provide evidence for the t -channel exchange of a colorless, C -odd gluonic compound, also known as the odderon. We combine these results with a TOTEM analysis of th…
9-Month Clinical and Angiographic Outcomes of the COBRA Polyzene-F NanoCoated Coronary Stent System
2016
Abstract Objectives The aim of this study was to assess the safety and effectiveness of the COBRA Polyzene-F NanoCoated Coronary Stent System (CeloNova Biosciences, San Antonio, Texas) for the treatment of de novo coronary artery lesions. Background Polyzene-F–coated coronary stents have shown reduced thrombogenicity and inflammation in preclinical studies. Methods Patients with de novo coronary artery lesions meeting eligibility criteria were enrolled in a nonrandomized, prospective clinical trial. The primary endpoint was target vessel failure (TVF) (defined as a composite of cardiac death, myocardial infarction, or clinically driven target vessel revascularization) at 9 months. A pre-spe…
When Physical Activity Participation Promotes Inactivity
2010
This article analyses negative experiences in physical education and sport reported during qualitative interviews of a group of inactive adolescent Spanish boys and girls. The purpose of this analysis is twofold. First and most important, it seeks to give voice to these young people reporting negative experiences and connect them to contexts of physical activity and sport in which they occurred in order to show how, ironically, inactivity is an unintended consequence. Second, the authors attempt to connect inactivity through negative experiences by drawing on conceptual notions of a gendered performativity culture, and symbolic violence. The authors conclude by commenting on how these insi…
Evidence for aBs0π±State
2016
Made available in DSpace on 2022-04-28T19:03:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-07-07 We report evidence for a narrow structure, X(5568), in the decay sequence X(5568)→Bs0π±, Bs0→J/ψφ, J/ψ→μ+μ-, φ→K+K-. This is evidence for the first instance of a hadronic state with valence quarks of four different flavors. The mass and natural width of this state are measured to be m=5567.8±2.9(stat)-1.9+0.9(syst) MeV/c2 and Γ=21.9±6.4(stat)-2.5+5.0(syst) MeV/c2. If the decay is X(5568)→Bs∗π±→Bs0γπ± with an unseen γ, m(X(5568)) will be shifted up by m(Bs∗)-m(Bs0)∼49 MeV/c2. This measurement is based on 10.4 fb-1 of pp collision data at s=1.96 TeV collected by the D0 experiment at th…