0000000000020939

AUTHOR

Philippe Brunel

showing 12 related works from this author

Prevalence, risk factor burden, and severity of coronary artery disease in patients with heterozygous familial hypercholesterolemia hospitalized for …

2019

Individuals with heterozygous familial hypercholesterolemia (FH) are at high risk of early myocardial infarction (MI). However, coronary artery disease (CAD) burden of FH remains not well described, especially for French patients.The objective of this study was to assess the prevalence of FH and severity of CAD from a large database of a French regional registry of acute MI.All consecutive patients hospitalized for an acute MI in a multicenter database from 2001 to 2017 were considered. FH was diagnosed using an algorithm adapted from the Dutch Lipid Clinic Network criteria. The prevalence and clinical features of FH and the severity of CAD were assessed.Among the 11,624 patients included i…

Heterozygotemedicine.medical_specialtyEndocrinology Diabetes and Metabolism[SDV]Life Sciences [q-bio]Myocardial InfarctionFamilial hypercholesterolemia030204 cardiovascular system & hematologySeverity of Illness IndexCohort StudiesHyperlipoproteinemia Type IICoronary artery disease03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinePrevalenceInternal MedicinemedicineHumansIn patientRegistries030212 general & internal medicineMyocardial infarctionRisk factorAcute miLipid clinicAgedAged 80 and overNutrition and Dieteticsbusiness.industryCholesterol LDLMiddle AgedEzetimibemedicine.disease3. Good healthLarge cohortHospitalizationFranceHydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular Medicinebusiness
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0133: The Log Book as a new tool for the secondary prevention of coronary artery disease

2016

International audience; IntroductionThe Log book (LB) project was created by a multidisciplinary team of healthcare professionals from a regional care network and aimed to improve secondary prevention (SP) after acute myocardial infarction (MI) in Cote d’Or. LB includes information and advices for increasing self management of risk factors by the patient.MethodsA prospective interventional study on 469 patients hospitalised for an acute MI in the 2 Intensive Coronary Care unit of Côte d’Or (CHU Dijon and Clinique de Fontaine les Dijon) in 2012 and surviving at 1 year follow-up (FU). LB was randomly given at the time of their hospitalisation by the nursing team, also providing oral advices o…

medicine.medical_specialtyPediatrics030204 cardiovascular system & hematologyCoronary artery disease03 medical and health sciences0302 clinical medicine[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemMedicine030212 general & internal medicineMyocardial infarctionRisk factorAcute miSecondary preventionSelf-managementbusiness.industryPrevention[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemmedicine.disease3. Good healthMyocardial infarctionEmergency medicineCoronary care unitSelf careCardiology and Cardiovascular MedicinebusinessLog book
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P2485Log Book as a new tool for the secondary prevention of coronary artery disease

2017

Secondary preventionCoronary artery diseasemedicine.medical_specialtybusiness.industryInternal medicineCardiologyMedicineCardiology and Cardiovascular Medicinebusinessmedicine.diseaseEuropean Heart Journal
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0432: Impact of admission hyperglycemia on one-year mortality in non-diabetic patients admitted for rescue PCI: Data from the “Observatoire des infar…

2014

BackgroundRescue percutaneous coronary intervention (PCI) is associated with improved clinical outcomes for ST-segment myocardial infarction (STEMI) patients after failed fibrinolysis therapy. Hyperglycemia on admission has been shown to be a powerful predictor of mortality after acute myocardial infarction, particularly in non-diabetic patients. The aim of our study was to assess the predictive value of admission glucose levels on long-term mortality in patients with rescue PCI.Patients and MethodsFrom the “Observatoire des infarctus de Côte d’Or” (RICO) survey, 510 consecutive non-diabetic STEMI patients admitted to the intensive care unit for rescue PCI after failed fibrinolysis therapy …

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentPercutaneous coronary interventionmedicine.diseaseIntensive care unitSurgerylaw.inventionOne year mortalitysurgical procedures operativelawEmergency medicineConventional PCIFibrinolysismedicinecardiovascular diseasesMyocardial infarctionCardiology and Cardiovascular MedicinebusinessGlycemicNon diabeticArchives of Cardiovascular Diseases Supplements
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SYNTAX score is associated with in-hospital mortality as assessed by GRACE risk score in patients with acute myocardial infarction

2013

Coronary angiographymedicine.medical_specialtyFramingham Risk ScoreIn hospital mortalitybusiness.industryCoronary arteriosclerosisHospital mortalitymedicine.diseaseInternal medicineMedicineIn patientMyocardial infarctionMedical emergencyCardiology and Cardiovascular MedicineMulti vessel coronary artery diseasebusinessEuropean Heart Journal
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N-Terminal Fragment of Pro B-type Natriuretic Peptide as a Marker of Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention fo…

2015

Contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) is frequent and associated with long-term renal impairment and mortality. Early markers of CIN are needed to improve risk stratification. We aimed to assess whether N-terminal fragment of pro B-type natriuretic peptide (Nt-proBNP) could be associated with CIN. From the French regional RICO survey, all the consecutive patients who underwent primary PCI for STEMI, from January 1, 2001, to December 3, 2013, were included. Nt-proBNP circulating levels were assessed on admission. CIN was defined as an increase in serum creatinine26.5 μmol/L or50% within 48 to 7…

Malemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentPopulationContrast-induced nephropathyMyocardial InfarctionContrast MediaRisk AssessmentCohort StudiesPercutaneous Coronary InterventionRisk FactorsInternal medicineNatriuretic Peptide BrainNatriuretic peptidemedicineDiabetes MellitusHumanscardiovascular diseasesMyocardial infarctionProspective StudieseducationProspective cohort studyAgedAged 80 and overeducation.field_of_studybusiness.industryAge FactorsPercutaneous coronary interventionOdds ratioAcute Kidney InjuryMiddle Agedmedicine.diseasePrognosisPeptide Fragmentssurgical procedures operativeCase-Control StudiesConventional PCICardiologyFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersThe American journal of cardiology
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Cardiac rehabilitation and 5-year mortality after acute coronary syndromes: The 2005 French FAST-MI study.

2016

IF 2.271; International audience; Background. - Clinical studies have shown a beneficial effect of cardiac rehabilitation (CR) on mortality.Objective. - To study the effect of CR prescription at discharge on 5-year mortality in patients with acute myocardial infarction (AMI).Methods. - Participants, from the 2005 French FAST-MI hospital registry, were 2894 survivors at discharge, divided according to AMI type: ST-segment elevation myocardial infarction (STEMI; n=1523) and non-STEMI (NSTEMI; n=1371). The effect of CR prescription on mortality was analysed using a Cox proportional hazards model.Results. - At discharge, 22.1% of patients had a CR prescription. Patients referred to CR were youn…

MaleMESH: Chi-Square Distributionmedicine.medical_treatmentMESH : Acute Coronary SyndromeMyocardial InfarctionMESH : AgedMESH : Prospective StudiesCardiac rehabilitationMESH: Risk Assessment0302 clinical medicineMyocardial infarctionProspective StudiesReferral and ConsultationMESH: Treatment OutcomeRehabilitationMESH: Middle AgedGeneral MedicineMESH: Follow-Up Studies3. Good healthMESH: Myocardial InfarctionMESH : Patient DischargeCardiology and Cardiovascular Medicinemedicine.medical_specialtyAcute myocardial infarctionMortalitéRisk Assessment03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemHumansMESH : Middle AgedAcute Coronary SyndromeMESH: Kaplan-Meier EstimateAgedChi-Square DistributionMESH: HumansMESH : Chi-Square DistributionProportional hazards modelMESH: Patient DischargeMESH : HumansPatient survivalMESH : Follow-Up Studiesmedicine.diseaseMESH : Proportional Hazards ModelsMESH: Acute Coronary SyndromeST-segment elevation myocardial infarctionMESH: FemaleTime FactorsMESH: RegistriesKaplan-Meier Estimate030204 cardiovascular system & hematologyMESH : Referral and ConsultationMESH: Proportional Hazards ModelsOlder patientsRisk FactorsMESH: Risk FactorsMESH : Female030212 general & internal medicineRegistriesMESH : Risk AssessmentMESH: AgedEjection fractionNon–ST-segment elevation myocardial infarctionMiddle Aged[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemMESH : Risk FactorsPatient DischargeTreatment OutcomeFemaleFranceMESH : Time FactorsMESH : MaleMESH : Treatment OutcomeMESH: Multivariate AnalysisMESH : Kaplan-Meier EstimateMESH: Referral and ConsultationInternal medicineInfarctus du myocarde sans sus-décalage du segment STmedicineIn patientcardiovascular diseasesMedical prescriptionMortalityRéadaptation cardiaqueMESH : FranceProportional Hazards Modelsbusiness.industryInfarctus du myocarde avec sus-décalage du segment STMESH: Time FactorsMESH : Multivariate AnalysisMESH: MaleMESH: Prospective StudiesSurgeryMESH: FranceInfarctus du myocarde aiguMultivariate AnalysisMESH : Myocardial InfarctionbusinessMESH : RegistriesFollow-Up Studies
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Impact of admission hyperglycemia on one-year mortality in non-diabetic patients admitted for rescue PCI

2013

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentCardiogenic shockPercutaneous coronary interventionInfarctionmedicine.diseaseIntensive care unitlaw.inventionlawDiabetes mellitusEmergency medicineConventional PCIMedicineMyocardial infarctionMedical emergencyCardiology and Cardiovascular MedicinebusinessNon diabeticEuropean Heart Journal
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Classification of coronary artery bifurcation lesions and treatments: time for a consensus

2008

Background: Percutaneous coronary intervention (PCI) of coronary bifurcation lesions remains a subject of debate. Many studies have been published in this setting. They are often small scale and display methodological flaws and other shortcomings such as inaccurate designation of lesions, heterogeneity, and inadequate description of techniques implemented. Methods: The aim is to propose a consensus established by the European Bifurcation Club (EBC), on the definition and classification of bifurcation lesions and treatments implemented with the purpose of allowing comparisons between techniques in various anatomical and clinical settings. Results: A bifurcation lesion is a coronary artery na…

medicine.medical_specialtyBifurcation lesionmedicine.medical_treatmentCoronary AngiographyLesionProsthesis Implantationbifurcation lesionsAngioplastyTerminology as TopicmedicineHumansRadiology Nuclear Medicine and imagingclassification of bifurcation lesionsAngioplasty Balloon CoronaryClassification of bifurcation lesionBifurcationQCA.QCAbusiness.industryCoronary StenosisPercutaneous coronary interventionStentGeneral MedicineClassification of treatmentmedicine.anatomical_structureHomogeneousConventional PCISettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREStentsRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessArtery
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Pre-Infarction Angina and Outcomes in Non-ST-Segment Elevation Myocardial Infarction: Data from the RICO Survey

2012

BACKGROUND: The presence of pre-infarction angina (PIA) has been shown to confer cardioprotection after ST-segment elevation myocardial infarction (STEMI). However, the clinical impact of PIA in non-ST-segment elevation myocardial infarction (NSTEMI) remains to be determined. METHODS AND RESULTS: From the obseRvatoire des Infarctus de Côte d'Or (RICO) survey, 1541 consecutive patients admitted in intensive care unit with a first NSTEMI were included. Patients who experienced chest pain <7 days before the episode leading to admission were defined as having PIA and were compared with patients without PIA. Incidence of in-hospital ventricular arrhythmias (VAs), heart failure and 30-day mortali…

MaleNon-Clinical MedicineMyocardial Infarctionlcsh:MedicineInfarctionCoronary AngiographyCardiovascularChest painAnginaIschemiaST segmentProspective StudiesMyocardial infarctionlcsh:ScienceMultidisciplinaryData CollectionClinical PharmacologyMiddle AgedAnginaPrognosisTreatment OutcomeCardiologyMedicineFemaleFrancemedicine.symptomResearch ArticleDrugs and Devicesmedicine.medical_specialtyCritical CareCardiologyHealth InformaticsCardiovascular PharmacologyAngina PectorisIntensive careInternal medicinemedicineHumansAgedHealth Care Policybusiness.industrylcsh:RArrhythmias Cardiacmedicine.diseaseHealth SurveysHeart failureMultivariate AnalysisMyocardial infarction complicationslcsh:QHealth StatisticsbusinessPLoS ONE
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Post-infectious myocardial Infarction: Does percutaneous coronary intervention improve outcomes? A propensity-score matched analysis

2020

Acute infection is a frequent trigger of myocardial infarction (MI). However, whether percutaneous coronary intervention (PCI) improves post-infectious MI prognosis is a major but unsolved issue. In this prospective multicenter study from coronary care units, we performed propensity score-matched analysis to compare outcomes in patients with and without PCI for post-infectious MI with angiography-proven significant coronary stenosis (&gt

medicine.medical_specialtyrespiratory tract infectionmedicine.medical_treatmentlcsh:Medicine030204 cardiovascular system & hematologyArticletype 2 myocardial infarctionCoronary artery disease03 medical and health sciences0302 clinical medicineInternal medicinemedicinepneumonia030212 general & internal medicinecardiovascular diseasesMyocardial infarctionProspective cohort studycoronary care unitbusiness.industrylcsh:Rpercutaneous coronary interventionPercutaneous coronary interventionGeneral Medicinemedicine.diseasemortalityStenosismyocardial infarctionsurgical procedures operativeConventional PCIPropensity score matchingCoronary care unitoutcomeCardiologyObservational studyCardiology and Cardiovascular Medicinebusinessacute infectionArchives of Cardiovascular Diseases Supplements
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0437: SYNTAX score is associated with in-hospital mortality as assessed by GRACE risk score in patients with acute myocardial infarction

2014

BackgroundCurrent guidelines for the management of patients with acute myocardial infarction (AMI) recommend the GRACE score for risk stratification with assessment of admission variables. The syntax score (SS) is a comprehensive angiographic scoring system that is derived entirely from the coronary anatomy and lesion characteristics. We investigated the relationship between severity of coronary artery disease (CAD) assessed with SYNTAX Score (SS) and GRACE Score (GS) in patients with AMI.Patients and MethodsFrom the obseRvatoire des Infarctus de Côte d’Or (RICO) survey, 614 consecutive patients hospitalized for an AMI from 1st march 2011 to 30 august 2012 and who underwent coronary angiogr…

medicine.medical_specialtyScoring systemFramingham Risk ScoreIn hospital mortalitybusiness.industryCoronary anatomymedicine.diseaseSurgeryLesionCoronary artery diseaseInternal medicinemedicineIn patientMyocardial infarctionmedicine.symptombusinessCardiology and Cardiovascular MedicineArchives of Cardiovascular Diseases Supplements
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