0000000000023881

AUTHOR

G.f. Ayala

showing 4 related works from this author

Towards a genetic history of Sicily

2000

ArcheologyGeographyChemistry (miscellaneous)Materials Science (miscellaneous)ConservationGeneral Economics Econometrics and FinanceSpectroscopy
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Suggestive evidence for association of D2S2188 marker (2q31.1) with autism in 143 Sicilian (Italian) TRIO families

2005

We have screened 143 Sicilian (Italian) families with one autistic child to verify, by a linkage disequilibrium approach, the involvement of the 2q31.1 region in the cause of the disease in these families. Our study design includes the use of intrafamilial association to prevent a population stratification bias and ethnic homogeneity of the sample. The results of our analysis provided suggestive evidence of the occurrence of transmission disequilibrium between autism and the D2S2188 polymorphism in Sicilian TRIO families, a finding which provides further and independent support to the hypothesis of the existence of a susceptibility gene (or genes) for autism on chromosome 2q.

Genetic MarkersLinkage disequilibriumDisequilibriumEthnic groupautism ds2188 pcrDiseaseBiologyPopulation stratificationSettore BIO/13 - Biologia ApplicataPolymorphism (computer science)GeneticsmedicineHumansFamilyAutistic DisorderSicilyBiological PsychiatryGenetics (clinical)GeneticsPolymorphism GeneticChromosome Mappingmedicine.diseaselanguage.human_languagePsychiatry and Mental healthChromosomes Human Pair 2languageAutismmedicine.symptomSicilianPsychiatric Genetics
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Lack of association of HOXA1 and HOXB1 mutations and autism in Sicilian (Italian) patients

2003

Lack of association of HOXA1 and HOXB1 mutations and autism in Sicilian (Italian) patients

Homeodomain Proteinsmedicine.medical_specialtyanimal structuresGenetic LinkageBiologymedicine.diseasebehavioral disciplines and activitieslanguage.human_languageCellular and Molecular NeurosciencePsychiatry and Mental healthmental disordersembryonic structuresmedicinelanguageHumansAutismAutistic DisorderAssociation (psychology)PsychiatrySicilyMolecular BiologySicilianTranscription FactorsMolecular Psychiatry
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Mutations and polymorphisms of the PAH gene in Sicily: comparison with other DNA polymorphisms

2000

GeneticsArcheologyChemistry (miscellaneous)Materials Science (miscellaneous)Dna polymorphismConservationBiologyGeneral Economics Econometrics and FinanceGeneSpectroscopyJournal of Cultural Heritage
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