0000000000025096

AUTHOR

Dirk T. Leube

showing 2 related works from this author

Low concentration of ziprasidone in human milk: a case report

2009

Although second-generation antipsychotics are established as the first-line treatment for schizophrenia, female patients are often excluded from this efficient treatment for safety reasons in pregnancy or whilst breastfeeding. For this reason, research on this subject mostly relies on case reports, although there is a great need to establish modern guidelines for treatment. Milk-to-plasma (M:P) ratios have been reported for clozapine (2.79–4.32; Winans, 2001), olanzapine (0.10–0.84; Gardiner et al. 2003), risperidone/9-OH risperidone (0.10–0.42/0.24–0.50; Gentile, 2004) and aripiprazole (0.18–0.20; Schlotterbeck et al. 2007). According to one case report, the infant ingests 0.09–0.43% of th…

PharmacologyOlanzapinemedicine.medical_specialtyPediatricsRisperidonebusiness.industryBreastfeedingPsychiatry and Mental healthPsychiatric historymedicinePsychiatric hospitalQuetiapinePharmacology (medical)AripiprazoleZiprasidonebusinessPsychiatrymedicine.drugThe International Journal of Neuropsychopharmacology
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Aripiprazole in human milk

2007

Second-generation antipsychotics are now the established first-line treatment for schizophrenia. However, there are limited data on the use of these compounds in pregnant and breastfeeding women with mental disorders. For ethical reasons, research on these subjects mostly relies on collection of single datasets of cases in order to establish treatment guidelines.

Pharmacologymedicine.medical_specialtybusiness.industryBreastfeedingMEDLINEHuman metabolismmedicine.diseasePsychiatry and Mental healthSchizophreniamedicinePharmacology (medical)AripiprazolePsychiatrybusinessmedicine.drugThe International Journal of Neuropsychopharmacology
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