Kutane und systemische Veränderungen mit Ähnlichkeiten zum Omenn‐Syndrom bei heterozygoter Mutation im RAG2‐Gen

2021

Keratoacanthoma Centrifugum Marginatum (KCM) after photodynamic therapy with good response to oral retinoids and topical 5‐fluorouracil

2019

Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma (KA), characterized by progressive peripheral growth, and usually devoid of deep invasion. Different systemic (oral retinoids) or topical treatments have been reported, but there is not a well-defined therapeutic protocol. We report the case of a KCM developing after photodynamic therapy (PDT) on the right leg of a 64-year-old woman. It was treated successfully with oral acitretin combined with topical 5-Fluorouracil + salicylic acid for 5 months. This is the first case of KCM developing after PDT and successfully treated with oral retinoid combined with topical treatment.

Asymptomatic erythematous hardened plaque on the scalp

2018

A heterozygous mutation in the RAG2 gene with cutaneous and systemic manifestations partially resembling Omenn syndrome

2021

Ulcerative pyoderma gangrenosum associated with cocaine use

2020

Pioderma gangrenoso ulcerativo por consumo de cocaína

2020

Morpheaform Plaques and an Infiltrated Scar: Answer.

2021

Síndrome de Gianotti-Crosti-like secundario a Molluscum contagiosum

2020

Characteristics of mucocutaneous vascular malformations drawn from a decade of a multidisciplinary committee experience.

2021

Vascular malformations (VM) are congenital, benign, and relatively frequent lesions. Scant data have been published about the epidemiology, clinical presentation, and treatment of VM from a dermatologist's perspective. The substantial differences between subtypes, broad range of specialists consulted and confusing nomenclature used over previous years may hamper a correct diagnosis. The main objective of this study is to describe VM epidemiology. As a secondary endpoint we evaluate clinical characteristics, clinical-radiological correlation and treatment approaches. We carried out an observational, descriptive, retrospective study. Cases presented to the multidisciplinary committee of our h…

Depressed indurated plaque with elastorrhexis as a distinctive lesion in Buschke‐Ollendorff syndrome

2020

Buschke-Ollendorff syndrome (BOS) is a rare autosomal dominant genodermatosis caused by heterozygous mutations in LEMD3 and characterized by connective tissue nevi and sclerotic bone lesions known as osteopoikilosis. We report a family with three individuals affected by BOS, two of whom manifested clinical and histopathological peculiarities, presenting with a depressed indurated plaque as the main cutaneous manifestation instead of the classic connective tissue nevi. Notable elastorrhexis was present in both biopsies.

Cutaneous manifestations in COVID‐19: a new contribution

2020

Abstract We have read with great interest Dr Recalcati’s review about skin manifestations in COVID‐19 as it is the first report on this subject1. In a recent review on clinical characteristics of coronavirus disease 2019 in China, rash was observed in 0,2% of cases2. However, from the trained eyes of a dermatologist, this percentage may be higher.

Levetiracetam‐induced pediatric toxic epidermal necrolysis successfully treated with etanercept

2020

Successful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor-α inhibitors has been described in adults, but few cases have been reported in children. To date, only four pediatric cases of TEN treated with infliximab and one with etanercept have been published. We present the case of an 8-year-old boy diagnosed with TEN induced by levetiracetam, successfully treated with etanercept, systemic corticosteroids, and intravenous immunoglobulin.

A pigmented and eroded lesion on the buttock.

2019

Pseudoxanthoma elasticum‐like syndrome with coagulation deficiency associated with carotid artery hypoplasia and a novel gamma‐glutamyl carboxylase g…

2020

Morpheaform Plaques and an Infiltrated Scar: Challenge

2021

Estudio retrospectivo de hemangiomas infantiles: Características clínicas, perinatales y factores predictores del desarrollo de secuelas residuales

2021

Resumen Introduccion El hemangioma infantil (HI) es el tumor mas frecuente de la infancia. Es un tumor benigno de origen vascular, que afecta a la edad pediatrica exclusivamente. La mayoria sigue un curso clinico benigno y se resuelve sin necesidad de tratamiento, aunque con frecuencia origina lesiones residuales una vez resuelto. El objetivo de este estudio fue realizar un estudio descriptivo de los HI evaluados en un hospital terciario, evaluar la incidencia de lesiones residuales y predecir los factores relacionados con el desarrollo de las mismas. Material y metodos Se realizo un estudio observacional retrospectivo recogiendo los HI de los que se disponia de imagenes clinicas evaluados …