0000000000038552

AUTHOR

Jelena Kotur-stevuljevic

showing 2 related works from this author

Atherogenic dyslipidemia and oxidative stress: a new look

2009

Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with antioxidants might reduce vascular events. Oxidative modifications of low-density lipoproteins (LDL) represent an early stage of atherosclerosis, and small, dense LDL are more susceptible to oxidation than larger, more buoyant particles. Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis. Recent studies suggested that novel therapeutic strategies may take into account the removal of such particles from circulation. Future research is required …

medicine.medical_specialty10265 Clinic for Endocrinology and Diabetology610 Medicine & healthOxidative phosphorylation030204 cardiovascular system & hematology2704 Biochemistry (medical)medicine.disease_causeAtherogenic dyslipidemia oxidative stressCoronary artery disease03 medical and health sciences2737 Physiology (medical)0302 clinical medicinePhysiology (medical)Internal medicineHumansMedicineDyslipidemias030304 developmental biologySubclinical infectionchemistry.chemical_classification0303 health sciencesReactive oxygen speciesAtherogenic dyslipidemiabusiness.industryVascular diseaseBiochemistry (medical)Public Health Environmental and Occupational HealthAtherogenic dyslipidemia2739 Public Health Environmental and Occupational HealthGeneral MedicineAtherosclerosismedicine.disease3. Good healthLipoproteins LDLOxidative StressEndocrinologychemistrybusinessOxidized ldlOxidative stressTranslational Research
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Alteration in Redox Status and Lipoprotein Profile in COVID-19 Patients with Mild, Moderate, and Severe Pneumonia

2022

Background. Metabolic alterations, particularly disorders of lipoprotein metabolism in COVID-19, may affect the course and outcome of the disease. This study aims at evaluating the lipoprotein profile and redox status in SARS-CoV-2 infected patients with different pneumonia severity and their association with lethal outcomes. Methods. The prospective cohort study was performed on 98 COVID-19 patients with mild, moderate, and severe pneumonia. Lipid and inflammatory parameters, lipoprotein subclasses, and redox status biomarkers were determined at the study entry and after one week. Results. Compared to patients with mild and moderate pneumonia, severely ill patients had higher oxidised low-…

AgingArticle SubjectoxidationSARS-CoV-2LipoproteinsHumansCOVID-19Cell BiologyGeneral MedicineProspective StudiesBiochemistryOxidation-ReductionAntioxidants
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