0000000000039878

AUTHOR

Laura Boix-garcía

showing 3 related works from this author

Oxidant/antioxidant status in obese children compared to pediatric patients with type 1 diabetes mellitus.

2009

Codoner-Franch P, Pons-Morales S, Boix-Garcia L, Valls-Belles V. Oxidant/antioxidant status in obese children compared to pediatric patients with type 1 diabetes mellitus. Background: Type 1 diabetes (T1D) mellitus and obesity are recognized risk factors for cardiovascular disease (CVD). A common mechanism underlying an increased risk for endothelial dysfunction in these two metabolic diseases is oxidative stress. Objective: To evaluate and compare the oxidant/antioxidant defense systems in children affected with T1D or obesity in order to determine the importance of oxidative stress before the emergence of complications. Subjects: Children with T1D (n = 20) or obesity (n = 22), without com…

Malemedicine.medical_specialtyLipid PeroxidesAntioxidantErythrocytesAdolescentEndocrinology Diabetes and Metabolismmedicine.medical_treatmentalpha-TocopherolProtein oxidationmedicine.disease_causeLipid peroxidationProtein Carbonylationchemistry.chemical_compoundInternal medicineMalondialdehydeInternal MedicinemedicineHumansObesityProspective StudiesChildRetrospective Studieschemistry.chemical_classificationType 1 diabetesGlutathione Peroxidasebusiness.industryGlutathione peroxidaseMalondialdehydemedicine.diseasebeta CaroteneObesityGlutathioneOxidative StressEndocrinologyDiabetes Mellitus Type 1chemistryPediatrics Perinatology and Child HealthFemaleLipid PeroxidationbusinessOxidative stressPediatric diabetes
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Retinol-Binding Protein 4 Levels Are Associated with Measures of Liver and Renal Function and Oxidant/Antioxidant Status in Obese Children

2013

Serum retinol-binding protein 4 (RBP4) has been proposed as a metabolic risk factor in obesity. We found that RBP4 levels also were associated with liver enzymes and cystatin C. Oxidant stress is a significant feature in obese children with greater values of RBP4 that can mediate the development of comorbidities.

Malemedicine.medical_specialtyAdolescentRenal functionKidneyKidney Function TestsAntioxidantschemistry.chemical_compoundLiver Function TestsInternal medicinemedicineHumansObesityChildRetinol binding protein 4biologybusiness.industryMetabolic riskOxidant antioxidantGlutathioneOxidantsmedicine.diseaseObesityOxidative StressEndocrinologyLiverchemistryCystatin CPediatrics Perinatology and Child Healthbiology.proteinFemaleCystatinbusinessRetinol-Binding Proteins PlasmaThe Journal of Pediatrics
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Is obesity associated with oxidative stress in children?

2009

We evaluated the presence of oxidative stress in obese children without co-morbidities.The study population included 68 children (30 girls, 38 boys), between 6 and 14 years of age. The levels of markers of oxidative damage (malondialdehyde [MDA], and plasma carbonyl groups [CG]) and measures of antioxidant defense, such as the enzyme glutathione peroxidase (GPx) and low molecular scavengers (erythrocyte-reduced glutathione [GSH], alpha-tocopherol and beta-carotene) were determined. Children were categorized in groups by the standard deviation score of body mass index (SDS-BMI). Twenty children were non-obese (SDS-BMIor =1.33), and the 48 obese children (SDS-BMIor =2) were further divided in…

Malemedicine.medical_specialtyAntioxidantAdolescentmedicine.medical_treatmentalpha-Tocopherolmedicine.disease_causeAntioxidantsBody Mass IndexProtein Carbonylationchemistry.chemical_compoundHigh-density lipoproteinMalondialdehydeInternal medicinemedicineHumansObesityProspective StudiesChildchemistry.chemical_classificationGlutathione PeroxidaseNutrition and Dieteticsbusiness.industryGlutathione peroxidaseHealth PolicyCholesterol HDLPublic Health Environmental and Occupational HealthGlutathionebeta Carotenemedicine.diseaseMalondialdehydeGlutathioneObesityOxidative StressCholesterolCross-Sectional StudiesEndocrinologychemistrySpainCase-Control StudiesPediatrics Perinatology and Child HealthFemalebusinessBody mass indexBiomarkersOxidative stressInternational Journal of Pediatric Obesity
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