6533b839fe1ef96bd12a66d4

RESEARCH PRODUCT

Retinol-Binding Protein 4 Levels Are Associated with Measures of Liver and Renal Function and Oxidant/Antioxidant Status in Obese Children

Raquel Simó-jordáAlba Faus-pérezClara Pérez-ramblaAntonio Mora-herranzLaura Boix-garcíaPilar Codoñer-franch

subject

Malemedicine.medical_specialtyAdolescentRenal functionKidneyKidney Function TestsAntioxidantschemistry.chemical_compoundLiver Function TestsInternal medicinemedicineHumansObesityChildRetinol binding protein 4biologybusiness.industryMetabolic riskOxidant antioxidantGlutathioneOxidantsmedicine.diseaseObesityOxidative StressEndocrinologyLiverchemistryCystatin CPediatrics Perinatology and Child Healthbiology.proteinFemaleCystatinbusinessRetinol-Binding Proteins Plasma

description

Serum retinol-binding protein 4 (RBP4) has been proposed as a metabolic risk factor in obesity. We found that RBP4 levels also were associated with liver enzymes and cystatin C. Oxidant stress is a significant feature in obese children with greater values of RBP4 that can mediate the development of comorbidities.

https://doi.org/10.1016/j.jpeds.2013.03.060