0000000000049772
AUTHOR
I. Escandell
showing 7 related works from this author
Remisión espontánea de verrugas recalcitrantes en niñas tras vacunación frente al virus del papiloma humano
2016
Nodular Lesion in Cheek With a Hair Tuft
2017
Trichostasis spinulosa is a rarely diagnosed disorder of the pilosebaceous unit, characterized by retention of telogen hairs within the dilated follicles. A hair tuft can be seen protruding from the follicles. We present a case of trichostasis spinulosa associated with intradermal melanocytic nevi, where dermoscopy helps to identify this entity.
Pruriginous Lesions in a Young Girl: Challenge.
2018
Novel Immunologic Approaches to Melanoma Treatment
2017
Approaches to treating melanoma have changed radically since the introduction of immunotherapy, and survival figures are now higher than possible with earlier therapies. The immunomodulators currently available mainly block CTLA-4 (cytotoxicT lymphocyte-associated molecule-4) and PD-1 (programed cell death protein 1) translocated to the cell surface, where they inhibit the antitumor immune response. Treatments blocking these molecules are being more widely used. Research now seeks new molecular targets, the best combinations of available drugs, and biomarkers that can identify ideal candidates for each one.
Novedades en inmunología del melanoma
2017
Resumen Desde la introduccion de la inmunoterapia el tratamiento del melanoma ha sufrido una revolucion, consiguiendose cifras de supervivencia superiores a las que se alcanzaban con los tratamientos previos. Los farmacos inmunomoduladores disponibles actualmente van dirigidos principalmente frente a las moleculas de superficie CTLA-4 y PD-1, que ejercen un efecto inhibidor sobre la respuesta inmune antitumoral. Se trata de un tratamiento en pleno proceso de expansion, y la investigacion se dirige hacia el descubrimiento de nuevas moleculas, las combinaciones de los farmacos disponibles o la identificacion de biomarcadores que permitan seleccionar a los pacientes idoneos para cada terapia.