0000000000054277

AUTHOR

Piergiorgio Cianciullo

0000-0003-0292-8892

showing 2 related works from this author

Dihydrophenanthrenes from a Sicilian Accession of Himantoglossum robertianum (Loisel.) P. Delforge Showed Antioxidant, Antimicrobial, and Antiprolife…

2021

The peculiar aspect that emerges from the study of Orchidaceae is the presence of various molecules, which are particularly interesting for pharmaceutical chemistry due to their wide range of biological resources. The aim of our study was to investigate the properties of two dihydrophenanthrenes, isolated, for the first time, from Himantoglossum robertianum (Loisel.) P. Delforge (Orchidaceae) bulbs and roots. Chemical and spectroscopic study of the bulbs and roots of Himantoglossumrobertianum (Loisel.) P. Delforge resulted in the isolation of two known dihydrophenanthrenes—loroglossol and hircinol—never isolated from this plant species. The structures were evaluated based on 1H-NMR, 13C-NMR…

dihydrophenanthrenes; <i>Himantoglossum robertianum</i>; NMR; antioxidant enzymes; antimicrobial activity; anti-proliferative activity; proapoptotic activityantimicrobial activityantioxidant enzymeEcologyproapoptotic activityBotany<i>Himantoglossum robertianum</i>Plant SciencedihydrophenanthreneNMRHimantoglossum robertianumQK1-989anti-proliferative activityAntioxidant enzymesEcology Evolution Behavior and SystematicsDihydrophenanthrenesPlants
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The chemical composition of the aerial parts of Stachys spreitzenhoferi (Lamiaceae) growing in Kythira Island (Greece), and their antioxidant, antimi…

2022

The Stachys L. genus has been used in traditional medicine to treat skin inflammations, stomach disorders, and stress. The aim of this study was to investigate the chemical profile and biological activity of the methanolic extract of Stachys spreitzenhoferi Heldr. (Lamiaceae) aerial parts, collected on the island of Kythira, South Greece. The analysis by liquid chromatography coupled with electrospray ionization and high-resolution mass spectrometry [LC-(-)ESI/HRMSn] of the methanol extract revealed the occurrence of thirty-six compounds - flavonoids, phenylethanoid glycosides, iridoids, quinic acid derivatives, aliphatic alcohol glycosides, and oligosaccharides - highlighting the substanti…

Staphylococcus aureusQuinic AcidPlant ScienceAntiproliferative activityHorticultureAntimicrobial activityBiochemistryAntioxidantsAntimicrobial activity; Antioxidant effects; Antiproliferative activity; LC-(−)ESI/HRMS(n); Lamiaceae; Stachys spreitzenhoferi Heldr.; Anti-Bacterial Agents; Antioxidants; Flavonoids; Glycosides; Greece; Humans; Iridoids; Methanol; Plant Components Aerial; Plant Extracts; Quinic Acid; Reactive Oxygen Species; Staphylococcus aureus; Superoxide Dismutase; U937 Cells; Anti-Infective Agents; Lamiaceae; StachysAnti-Infective AgentsHumansIridoidsStachys spreitzenhoferi HeldrGlycosidesMolecular BiologyFlavonoidsLamiaceaeGreecePlant ExtractsSuperoxide DismutaseMethanolStachys spreitzenhoferi Heldr.LC-(−)ESI/HRMS(n)AerialGeneral MedicineU937 CellsAntioxidant effectPlant Components AerialAnti-Bacterial AgentsAntioxidant effectsStachysPlant ComponentsReactive Oxygen Species
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