0000000000054299

AUTHOR

Christophe Dubois

Outcome of urgent and elective percutaneous coronary interventions after pharmacologic reperfusion with tenecteplase combined with unfractionated heparin, enoxaparin, or abciximab

Item does not contain fulltext OBJECTIVES: The aim of this study was to evaluate percutaneous coronary intervention (PCI) in the Assessment of the Safety and Efficacy of New Thrombolytic Regimens (ASSENT-3) trial. BACKGROUND: In the ASSENT-3 trial, co-therapy with abciximab (ABC) or enoxaparin (ENOX) reduced ischemic complications after ST-elevation acute myocardial infarction treated with tenecteplase when compared with unfractionated heparin (UFH). The effect of these new co-therapies on the results of PCI is unknown. METHODS: Clinical outcomes in patients who received co-therapy with ABC, ENOX, or UFH and subsequently underwent an elective (n = 1,064) or urgent (n = 716) PCI in the ASSEN…

research product

Composition nutritionnelle des plats complets végétariens et non-végétariens proposés en restauration scolaire : une étude du collectif EnScol

Context: In France, since 1 November 2019, all school restaurants are required to offer a vegetarian menu at least once a week. This study was initiated and co-developed by researchers and school catering professionals from the « EnScol » team.Aim: To assess the nutritional content of vegetarian dishes served in school meals in France.Methods: The nutritional content of main dishes (i.e. the combination of protein dish and side dish) was studied and compared according to whether the dishes were vegetarian (n=315) or non-vegetarian (n=669). Within the vegetarian main dishes, three categories were defined and compared: dishes without any ingredient of animal origin, dishes with cheese, and di…

research product

CKD NUTRITION, INFLAMMATION AND OXIDATIVE STRESS

Introduction and Aims: Serum p-cresyl sulfate associates with cardiovascular disease in patients at different stages of chronic kidney disease. p-Cresyl sulfate concentrations are determined by intestinal uptake of p-cresol, human metabolism to p-cresyl sulfate and renal clearance. Whether intestinal uptake of p-cresol itself is associated with cardiovascular disease in patients with renal disease has not been studied to date. Methods: We performed a prospective study in patients with chronic kidney disease stage 1-5 (clinicaltrials.gov NCT00441623). Intestinal uptake of p-cresol, under steady state conditions, was estimated from 24h urinary excretion of p-cresyl sulfate. Primary endpoint w…

research product