0000000000064289

AUTHOR

Francesco Stellato

showing 2 related works from this author

IRIDE: Interdisciplinary research infrastructure based on dual electron linacs and lasers

2014

This paper describes the scientific aims and potentials as well as the preliminary technical design of RUDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity "particles factory", based on a combination of high duty cycle radio-frequency superconducting electron linacs and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of sci…

Nuclear and High Energy PhysicsHigh energySC Linac;Neutron source;FEL;Compton source;Advanced accelerators concepts;Particle physicsSettore FIS/07 - FISICA APPLICATA (A BENI CULTURALI AMBIENTALI BIOLOGIA E MEDICINA)Advanced accelerators conceptTechnical designNOAdvanced accelerators conceptsParticle physicSC Linac; FEL; Particle physics; Neutron source; Compton source; Advanced accelerators conceptsInstrumentationFELPhysicsSC LinacSettore FIS/01 - Fisica SperimentaleAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linac; Instrumentation; Nuclear and High Energy PhysicsParticle physicsAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linac; Nuclear and High Energy Physics; InstrumentationCompton sourceNeutron sourceWide fieldSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Dual (category theory)Free Electron LaserAdvanced accelerators concepts Compton source FEL Neutron source Particle physics SC LinacAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linacadvanced accelerators concepts; particle physics; sc linac; compton source; fel; neutron sourceneutron sourcefree electron lasersSystems engineeringFactory (object-oriented programming)Free electron laser
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Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser

2014

We describe a method to measure ultrafast protein structural changes using time-resolved wide-angle X-ray scattering at an X-ray free-electron laser. We demonstrated this approach using multiphoton excitation of the Blastochloris viridis photosynthetic reaction center, observing an ultrafast global conformational change that arises within picoseconds and precedes the propagation of heat through the protein. This provides direct structural evidence for a 'protein quake': the hypothesis that proteins rapidly dissipate energy through quake-like structural motions. peerReviewed

Photosynthetic reaction centreMaterials scienceProtein ConformationPhysics::OpticsPhycobiliproteinsfrequency vibrational-modesRadiation DosageBiochemistryMolecular physicsArticlelaw.inventionProtein structureX-Ray Diffractionlawddc:570Scattering Small AngleMolecular Biologyta116Quantitative Biology::BiomoleculesScatteringLasersMolecular biophysicsFree-electron laserCell BiologyLaserstructural dynamicsEnergy TransferPicosecondBiophysicsUltrashort pulseBiotechnologyNature methods
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