0000000000083092
AUTHOR
H. Schönborn
Experimentelle Untersuchungen zur Speciesspezifität von Anti-Gamma-Globulinfaktoren
Nach Charakterisierung des Rheumafaktors bei der chronischen Polyarthritis durch Waaler [16], Rose [14] sowie Waller u. Vaughan [17] konnten Rheumafaktor-ahnliche Substanzen auch bei Fallen von Tuberkulose, Syphilis, Endokarditis lenta, bei Kollagenosen, Sarkoidosen, bei Lebererkrankungen und im Serum von Normalpersonen (Ubersich in [8]) beobachtet und zum Teil an Hand bestimmter Reaktionen vom Rheumafaktor abgegrenzt werden [3, 8, 19]. Es handelt sich bei den Faktoren um Antikorper vom 19 S-Typ [5], die gegen Human-Gamma-Globulin gerichtet sind und z. T. mit Gamma-Globulin anderer Species kreuzreagieren. Zur Entstehung der Rheumafaktoren nahmen Najjar [13] und Milgrom [10] unabhangig von e…
The influence of dopamine on hemodynamics, microcirculation and renal function in patients with hypnotic drug intoxication
The effect of dopamine on hemodynamics (CO, AoPm, TPR, SV, SW, CVP, PAPm, PAEDP), microcirculation (MBF, PS-product) and renal function (VU, CKI, CNa, CK, Cosm, TcH2O) was studied in 8 patients with hypnotic drug poisoning. With increasing doses of dopamine, cardiac output and heart rate increased and the peripheral resistance decreased. An augmentation of stroke volume and left ventricular stroke work was observed in the low dose range only (200--400 mug/min). With increasing doses, central venous pressure as well as mean pulmonary artery pressure and enddiastolic pulmonary artery pressure decreased. No vasoconstriction was found in muscle tissue vessels even with large doses of dopamine. …
Klinik und Morphologie der akuten peroralen Diquatintoxikation (Reglone)
Klinische Daten, morphologische Befunde und quantitative Giftanalysen einer letal verlaufenden akuten Intoxikation durch Trinken von Reglone (Diquat) werden beschrieben, da ahnliche Falle aus der Literatur bisher nicht bekannt sind.
Spread of hepatitis B virus infection among family contacts of asymptomatic HBsAg carriers
Family members of 34 asymptomatic HBsAg carriers were tested for different hepatitis B virus (HBV) markers. Among 67 family members tested 24 (36%) presented signs of a past or ongoing HBV-infection. Spread of HBV-infection was particularly high in those families in which the HBsAg carrier was positive for HBeAg and Dane particle-associated DNA polymerase activity. Non-parenteral “horizontal” transmission of HBV among spouses and brothers and sisters and probably parenteral vertical transmission of HBV from carrier mothers to their infants occurred in approximately the same frequency. Fathers transmitted HBV unfrequently to their offsprings. The results show that the risk to acquire a HBV-i…