0000000000089663

AUTHOR

Jia Nee Foo

0000-0001-9899-2308

showing 2 related works from this author

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

2013

The author manuscript of this article is open access and is freely available online at PubMed Central

medicine.medical_specialtyKeratoconusCorneal Pachymetrygenetic structuresthickness; keratoconus; geneGlaucomaOcular hypertensionGenome-wide association studyBiologyReal-Time Polymerase Chain ReactionKeratoconusWhite PeopleArticleCentral corneal thicknessCorneaAsian PeopleOphthalmologyCorneaOdds RatioGeneticsmedicineHumansCorneal pachymetrymedicine.diagnostic_testForkhead Box Protein O1Forkhead Transcription FactorsGlaucomaOdds ratioMicroarray Analysismedicine.diseaseConfidence intervaleye diseasesFibronectinsmedicine.anatomical_structureGenetic Locisense organsGenome-Wide Association Study
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Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.

2014

Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10 -20) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10 -11) near ETS1; 3q28 (rs6444305, p = 1.10 × 10 -10) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10 -10) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10 -8) near PVT1. In an analysis of the HLA region, we identified four linked HLA-DRß1 multiallelic amino acids at p…

EXPRESSIONFollicular lymphomaSingle-nucleotide polymorphismGenome-wide association studyHuman leukocyte antigenBiologyVARIANTSPolymorphism Single Nucleotidefollicular lymphomaHLA AntigensPolymorphism (computer science)ReportCLASS-IRESOURCEBiomarkers TumorGeneticsmedicineChromosomes HumanHumansTOOLGenetic Predisposition to DiseaseGenetics(clinical)PEPTIDEAlleleLymphoma FollicularAllelesGenetics (clinical)Genetic associationSNPSGeneticsRISKGenome-wide associationHaplotypemedicine.diseaseHLAHaplotypesCase-Control StudiesUNIVERSITYSETGenome-Wide Association Study
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