0000000000115401

AUTHOR

Alejandro Romero

showing 5 related works from this author

A combined dietary approach using isotope and dental buccal-microwear analysis of human remains from the Neolithic, Roman and Medieval periods from t…

2016

Stable isotope and dental-microwear analysis are methods commonly used to reconstruct dietary habits in modern and ancient human populations. However, it is rare that they are both used together in the same study, and here both methods are combined to obtain information on human dietary habits from the site of Tossal de les Basses (Alicante, Spain) through time. Middle Neolithic, Late Roman and Medieval (Islamic) individuals have been analyzed for carbon and nitrogen stable isotope ratios of bone collagen, as well as for buccal-dental microwear. Overall, δ13C and δ15N isotopic values show that for all periods the diet was mainly based on C3 terrestrial resources. However, the isotopic signa…

010506 paleontologyArcheologyNitrogenRestes humanes (Arqueologia)PopulationBiología Celular01 natural sciencesIsotopic signature0601 history and archaeologyMiddle Ageseducation0105 earth and related environmental sciences2. Zero hungereducation.field_of_studyBone collagen060102 archaeologyδ13C06 humanities and the artsδ15NArchaeologyCarbonDietGeographyHabitatPeriod (geology)Dental-microwearIberiaHuman
researchProduct

Genomic transformation and social organization during the Copper Age–Bronze Age transition in southern Iberia

2021

Description

010506 paleontologySouthern IberiaArgarArqueologiaBiología CelularCopper Age01 natural sciencesSocial and Interdisciplinary Sciences03 medical and health sciencesBronze AgePolitical scienceGeneticsread alignmentSocial organizationancient genomes030304 developmental biology0105 earth and related environmental sciences0303 health sciencesMultidisciplinaryEuropean researchskin color predictionancestrySciAdv r-articlesHuman GeneticsPrehistoriaChalcolithicsequencestepperevealAnthropologyprehistoryadmixtureChristian ministryhistoryBronce AgeHumanitiesResearch Article
researchProduct

Ten millennia of hepatitis B virus evolution

2021

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd…

Phylogeographic historyHepatitis B/history01 natural sciencesThe RepublicCommunicable Diseases EmergingGermanCommunicable Diseases Emerging/historyAgency (sociology)Science and technologyComputingMilieux_MISCELLANEOUSHistory AncientPhylogenymedia_common0303 health sciencesMultidisciplinaryAncient DNAEuropean researchvirus diseasesGenomicsHepatitis B3. Good healthEuropelanguageComputingMethodologies_DOCUMENTANDTEXTPROCESSINGChristian ministryPaleogenomic analysesAsian Continental Ancestry Group010506 paleontologyHepatitis B virusAsiaHepatitis B virus/classificationEuropean Continental Ancestry GroupLibrary scienceBiología CelularWhite PeopleMarie curieEvolution Molecular03 medical and health sciencesAmerican NativesAsian PeoplePolitical scienceGenomic datamedia_common.cataloged_instanceHumansSlovakEuropean unionAmerican Indian or Alaska Native030304 developmental biology0105 earth and related environmental sciencesGenetic VariationPaleontologyPrehistoriaA300language.human_languagedigestive system diseasesAmerican natives; Americas; Asia; Asian continental ancestry group; Communicable diseases Emerging; Europe; European continental ancestry group; Evolution molecular; Genetic variation; Genomics; Hepatitis B; Hepatitis B virus; History Ancient; Humans; Paleontology; PhylogenyAmericas
researchProduct

A History of the Pharmacological Treatment of Bipolar Disorder.

2018

In this paper, the authors review the history of the pharmacological treatment of bipolar disorder, from the first nonspecific sedative agents introduced in the 19th and early 20th century, such as solanaceae alkaloids, bromides and barbiturates, to John Cade’s experiments with lithium and the beginning of the so-called “Psychopharmacological Revolution” in the 1950s. We also describe the clinical studies and development processes, enabling the therapeutic introduction of pharmacological agents currently available for the treatment of bipolar disorder in its different phases and manifestations. Those drugs include lithium salts, valproic acid, carbamazepine, new antiepilep…

Farmacología veterinariamedicine.drug_classPsychopharmacologyFarmacologíaantipsychotic drugsAtypical antipsychoticCariprazineReviewPharmacologyLamotrigineLithiumHistory 21st CenturyCatalysisTreatment of bipolar disorderInorganic Chemistrylcsh:Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicinepharmacological treatmentmedicineAsenapineAnimalsHumansZiprasidoneantiepileptic drugsPhysical and Theoretical ChemistryMolecular Biologylcsh:QH301-705.5SpectroscopyPsiquiatríaLurasidonebipolar disorderbusiness.industrymood stabilizer drugsOrganic ChemistryHistory 19th CenturyGeneral MedicineHistory 20th Century030227 psychiatryComputer Science ApplicationsTranquilizing Agentschemistrylcsh:Biology (General)lcsh:QD1-999Quetiapinebusiness030217 neurology & neurosurgerymedicine.drug
researchProduct

The Bronze Age burials from Cova Dels Blaus (Vall d′Uixó, Castelló, Spain): An approach to palaeodietary reconstruction through dental pathology, occ…

2005

This paper reports a palaeodietary investigation of the human remains found in the collective Bronze Age burial cave from Vall d'Uixó (Castelló, Spain). Dental pathology, tooth wear as well as buccal dental microwear were analysed. Percentages of dental pathologies were compared with Chalcolithic and Bronze Age sites from the same territory. Dental caries, ante-mortem tooth loss, periodontal disease and abscess frequencies indicate a diet rich in carbohydrate foods. However, dental calculus percentages and macroscopic wear patterns suggest a diet not exclusively relying on agricultural resources. In addition, buccal dental microwear density and length by orientation recorded on micrographs …

MalePathologymedicine.medical_specialtyMeatDentistryDental CariesDental OcclusionTooth Lossstomatognathic systemCaveBronze AgeDietary CarbohydratesmedicineTooth lossHumansHistory AncientPaleodontologyOrthodonticsgeography.geographical_feature_categoryDental occlusionbusiness.industryCalculus (dental)Chalcolithicmedicine.diseaseDietstomatognathic diseasesGeographySpainTooth wearAnthropologyTooth pathologyFemalemedicine.symptomEdible GrainbusinessToothHOMO
researchProduct