0000000000115541

AUTHOR

Carmen Freire

showing 6 related works from this author

Residential Exposure to Outdoor Air Pollution during Pregnancy and Anthropometric Measures at Birth in a Multicenter Cohort in Spain

2011

Background: A growing body of research suggests that prenatal exposure to air pollution may be harmful to fetal development. We assessed the association between exposure to air pollution during pregnancy and anthropometric measures at birth in four areas within the Spanish Children’s Health and Environment (INMA) mother and child cohort study. Methods: Exposure to ambient nitrogen dioxide (NO2) and benzene was estimated for the residence of each woman (n = 2,337) for each trimester and for the entire pregnancy. Outcomes included birth weight, length, and head circumference. The association between residential outdoor air pollution exposure and birth outcomes was assessed with linear regress…

Questionnaires:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Environmental Monitoring [Medical Subject Headings]Fetus -- CreixementPediatricsHealth Toxicology and MutagenesisEspañaair pollution:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort StudiesbenzenebirthRecién NacidoPregnancyResidence CharacteristicsSurveys and Questionnaires:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Air Pollutants [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure [Medical Subject Headings]Birth WeightBody SizeMedicineProspective StudiesProspective cohort studyTamaño Corporal:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]Vehicle Emissions:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]Dióxido de NitrógenoPeso al NacerAir PollutantsInhalation ExposureanthropometryAdultoDistribución Espacial de la Población:Chemicals and Drugs::Complex Mixtures::Vehicle Emissions [Medical Subject Headings]Adulto JovenEstudios ProspectivosAire -- Contaminació -- Efectes fisiològics -- EpidemiologiaExposición MaternaHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Inhalation Exposure [Medical Subject Headings]Maternal ExposureFemeninaInfant Small for Gestational AgeCohort:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight::Infant Small for Gestational Age [Medical Subject Headings]:Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrogen Oxides [Medical Subject Headings]Emisiones de VehículosFemalepregnancyEnvironmental MonitoringCohort studyAdultmedicine.medical_specialty:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]nitrogen dioxideEmbarazoBirth weightMonitoreo del AmbienteExposición por Inhalación:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size [Medical Subject Headings]:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Young AdultRecién Nacido Pequeño para la Edad Gestacional:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansPregnancybusiness.industryResearchBencenoInfant NewbornPublic Health Environmental and Occupational Healthbirth weightAnthropometrymedicine.disease:Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Demography::Residence Characteristics [Medical Subject Headings]Confidence interval:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Cyclic::Hydrocarbons Aromatic::Benzene [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Prospective Studies [Medical Subject Headings]:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Contaminantes del AireSmall for gestational ageEstudios de CohortesbusinessDemographyEnvironmental Health Perspectives
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Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain

2011

Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during pregnancy through different water uses and evaluated the association with birth weight, small for gestational age (SGA), low birth weight (LBW), and preterm delivery. Methods: Mother–child cohorts set up in five Spanish areas during the years 2000–2008 contributed data on water ingestion, showering, bathing, and swimming in pools. We ascertained residential THM levels during pregnancy periods through ad hoc sampling campaigns (828 measurements) and regulatory data (264 me…

PediatricsFetus -- CreixementBathingHealth Toxicology and MutagenesisEspaña:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort Studies:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models Theoretical [Medical Subject Headings]small for gestational agePregnancynewbornFemeninosExposición a Riesgos Ambientales:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]water pollutionInfeccions respiratòries -- EpidemiologiaAdultodisinfection by-products:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight [Medical Subject Headings]Modelos TeóricosEnvironmental exposurepremature birthNacimiento PrematuroHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Premature birthInfant Small for Gestational AgeGestation:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight::Infant Small for Gestational Age [Medical Subject Headings]Femaleepidemiologymedicine.symptomAigua -- DepuracióAdultmedicine.medical_specialtytrihalomethanesContaminantes Químicos del AguaEmbarazoBirth weight:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Embaràs -- Aspectes nutricionalsRecién nacidoRecién Nacido Pequeño para la Edad GestacionalEnvironmental healthmedicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]cohort studyModelos LogísticosHumanslow birth weightEpidemiologiaRecién Nacido de Bajo Peso:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Halogenated::Trihalomethanes [Medical Subject Headings]Pregnancybusiness.industryTrihalometanoResearchPublic Health Environmental and Occupational HealthInfant Newbornbirth weightEnvironmental ExposureInfant Low Birth WeightModels Theoreticalmedicine.diseaseLow birth weightLogistic Models:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Small for gestational age:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Water Pollutants::Water Pollutants Chemical [Medical Subject Headings]:Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor Premature::Premature Birth [Medical Subject Headings]businessEstudios de CohortesWater Pollutants Chemical
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Trihalomethanes in swimming pool water in four areas of Spain participating in the INMA project

2010

ResumenObjetivoLa natación es uno de los deportes más practicados en España, por personas de todas las edades y condiciones físicas. También es una vía de exposición a subproductos de la desinfección, compuestos potencialmente tóxicos. Su concentración en el agua de las piscinas no está legislada y es poco conocida. El objetivo de este trabajo es describir la concentración de trihalometanos en el agua de piscinas de los municipios de cuatro cohortes del estudio INMA.MétodosEn julio de 2009 se analizaron los trihalometanos en el agua de piscinas (n=27) de Asturias, Granada, Valencia y Sabadell.ResultadosLa concentración media de trihalometanos totales fue de 42,7μg/l (desviación estándar [DE…

Subproductos de la desinfecciónPublic Health Environmental and Occupational HealthWaterAguaSwimming pool waterExposureSwimming poolTrihalomethanechemistry.chemical_compoundDisinfection by-productschemistryTrihalometanosExposiciónEnvironmental healthEnvironmental sciencehuman activitiesPiscinaTrihalomethanesGaceta Sanitaria
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Placental metal concentrations and birth outcomes: The Environment and Childhood (INMA) project

2019

To examine the association of placental levels of arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb), manganese (Mn), and chromium (Cr) with birth outcomes (birth weight, length, and head circumference, low birth weight [LBW], gestational age, preterm delivery, and small for gestational age [SGA]) in mother-child pairs from the Environment and Childhood (INMA) Project in Spain.Metal concentrations were measured in placenta tissue samples randomly selected from five INMA cohorts. Data on birth outcomes were obtained from medical records. Associations were assessed in a sub-sample of 327 mother-infant pairs by regression models adjusted for confounding factors and for all metals simultaneous…

AdultMalePlacentaBirth weightPhysiologyGestational Age010501 environmental sciences01 natural sciencesArsenicCohort StudiesFetal Development03 medical and health sciences0302 clinical medicinePregnancyMetals HeavyPlacentaBirth WeightHumansMedicine030212 general & internal medicineMaternal-Fetal ExchangePreterm delivery0105 earth and related environmental sciencesbusiness.industryConfoundingInfant NewbornPublic Health Environmental and Occupational HealthGestational agemedicine.diseaseLow birth weightmedicine.anatomical_structureMaternal ExposureSpainIn uteroSmall for gestational ageEnvironmental PollutantsFemalemedicine.symptombusinessHeadBiological MonitoringInternational Journal of Hygiene and Environmental Health
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Prenatal co-exposure to neurotoxic metals and neurodevelopment in preschool children: The Environment and Childhood (INMA) Project

2018

We sought to determine whether prenatal co-exposure to As, Cd, Hg, Mn, and Pb was associated with impaired neurodevelopment in preschool children from the Spanish Environment and Childhood (INMA) Project, using the placenta as exposure matrix. We measured metal levels in placenta tissue samples randomly selected from five of the seven population-based birth cohorts participating in the INMA Project, collected between 2000 and 2008. Neuropsychological assessment of cognitive and motor function was carried through the use of the McCarthy Scales of Children's Abilities (MSCA) at the age of 4-5years. Data on placental metal levels, MSCA scores, and relevant covariates was available for 302 chil…

Pediatricsmedicine.medical_specialtyEnvironmental EngineeringPlacentaGross motor skillPopulationNeuropsychological Tests010501 environmental sciences01 natural sciencesArsenic03 medical and health sciencesChild Development0302 clinical medicinePregnancyMetals HeavymedicineMemory spanHumansEnvironmental Chemistry030212 general & internal medicineNeuropsychological assessmentRisk factoreducationWaste Management and Disposal0105 earth and related environmental sciencesManganeseeducation.field_of_studymedicine.diagnostic_testbusiness.industryNeurotoxicityCognitionMercurymedicine.diseaseExecutive functionsPollutionLeadSpainChild PreschoolPrenatal Exposure Delayed EffectsFemalebusinessCadmiumScience of the Total Environment
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Association of placental concentrations of phenolic endocrine disrupting chemicals with cognitive functioning in preschool children from the Environm…

2020

Developmental exposure to bisphenol A (BPA) and other phenolic endocrine disrupting chemicals (EDCs) may affect child neurodevelopment, but data on the effects of prenatal exposure to phenols on cognitive function remain sparse. Our aim was to examine the association of placental concentrations of several phenolic EDCs, including BPA, parabens (PBs), and benzophenones (BzPs), with cognitive development in preschool children from the Environment and Childhood (INMA) Project in Spain. Concentrations of BPA, four PBs (methylparaben [MePB], ethylparaben [EtPB], propylparaben [PrPB], and butylparaben [BuPB]), and six BzPs (BzP-1, BzP-2, BzP-3, BzP-6, BzP-8, and 4-hydroxybenzophenone [4-OH-BzP]) …

MalePlacentaPhysiology010501 environmental sciencesEndocrine DisruptorsNeuropsychological Tests01 natural sciencesMotor function03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCognitionPhenolsPregnancyEndocrine systemMedicineHumans030212 general & internal medicineNeuropsychological assessmentCognitive skillBenzhydryl CompoundsAssociation (psychology)ChildPrenatal exposure0105 earth and related environmental sciencesGeneral Environmental ScienceButylparabenmedicine.diagnostic_testbusiness.industryConfoundingPublic Health Environmental and Occupational HealthchemistryChild PreschoolGeneral Earth and Planetary SciencesFemalebusinessClinical psychologyInternational journal of hygiene and environmental health
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