0000000000116640

AUTHOR

Raquel López-vilella

showing 11 related works from this author

The Female Sex Confers Different Prognosis in Heart Failure: Same Mortality but More Readmissions

2021

Introduction: Heart failure (HF) is a major cause of morbimortality both in men and women. Differences between sex in etiopathogenesis, response to treatment, and quality of care have been found in patients with HF. Females are usually under-represented in clinical trials and there is no solid evidence demonstrating the influence of sex in the prognostic of chronic HF. The primary objective of this study was to analyse the differences in mortality and probability of hospital readmission between males and females with HF. The secondary objective was to compare mortality and probability of hospital readmission by ejection fraction (reduced vs. preserved).Methods: Patients with decompensated H…

medicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemMultivariate analysisheart failuremorbidity030204 cardiovascular system & hematologyCardiovascular Medicinereadmissions03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineInternal medicinegenderMedicinesex030212 general & internal medicineOriginal ResearchHospital readmissionEjection fractionbusiness.industryFemale sexleft ventricular ejection fractionmedicine.diseaseResponse to treatmentmortalityClinical triallcsh:RC666-701Heart failureCardiologyCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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Impact of Circulatory Assistance in the Early Evolution After Heart Transplantation. Unicentric Experience.

2021

ABSTRACT Background Heart transplantation (HT) is the reference treatment for patients with terminal heart failure. In recent years there has been a progressive increase in HT procedures in patients who have a circulatory support (CS). Methods This is a retrospective single-center study of 293 consecutive patients who underwent HT from 2009 to 2018, analyzing the evolution of the 2 cohorts: patients with and without CS as a bridge to HT. Baseline and evolutionary clinical data collected following the usual follow-up protocol were recorded, including clinical events observed during the follow-up 1 year after the procedure. Results The subgroup of patients transplanted with CS showed a higher…

Heart transplantationMechanical ventilationHeart FailureTransplantationmedicine.medical_specialtyMultivariate analysisbusiness.industryIncidence (epidemiology)medicine.medical_treatmentOdds ratiomedicine.diseasePrognosisConfidence intervalHeart failureInternal medicineCirculatory systemmedicineCardiologyHeart TransplantationHumansSurgerybusinessFollow-Up StudiesRetrospective StudiesTransplantation proceedings
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Creatinine and NT-ProBNP levels could predict the length of hospital stay of patients with decompensated heart failure.

2021

Heart failure (HF) is a clinical syndrome that causes high morbidity and mortality with a high number of admissions and sometimes prolonged admissions. This study aimed at assessing whether parameters detected during the first 24 h of admission may predict a prolonged hospital stay in patients admitted to hospital for decompensated HF.From January 2016 to December 2019, 2359 admissions of decompensated HF were recorded. In-hospital transfers,Univariate differences were found at admission in NT-ProBNP, creatinine, history of cardiac surgery, smoking and alcoholism, left and right ventricular ejection fraction, systolic blood pressure and heart rate. The ROC analysis showed significant areas …

medicine.medical_specialty030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compoundHigh morbidity0302 clinical medicineNatriuretic Peptide BrainmedicineHumansDecompensation030212 general & internal medicineClinical syndromeHeart FailureCreatininebusiness.industryStroke VolumeGeneral MedicineLength of Staymedicine.diseasePeptide FragmentschemistryHeart failureCreatinineEmergency medicineVentricular Function RightCardiology and Cardiovascular MedicinebusinessHospital stayActa cardiologica
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Sensitivity and negative predictive value of treadmill exercise stress testing for the diagnosis of catecholaminergic polymorphic ventricular tachyca…

2015

TachycardiaMalemedicine.medical_specialtyStress testingTreadmill exerciseCatecholaminergic polymorphic ventricular tachycardiaVentricular Function LeftElectrocardiographyDna geneticsInternal medicineMedicineHumansmedicine.diagnostic_testVentricular functionbusiness.industryRyanodine Receptor Calcium Release ChannelGeneral MedicineDNAmedicine.diseasePredictive valueMutationCardiologyTachycardia VentricularFemalemedicine.symptombusinessElectrocardiographyRevista espanola de cardiologia (English ed.)
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Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron : The Myocardial- Trial

2020

Background Intravenous ferric carboxymaltose ( FCM ) improves symptoms, functional capacity, and quality of life in heart failure and iron deficiency. The mechanisms underlying these effects are not fully understood. The aim of this study was to examine changes in myocardial iron content after FCM administration in patients with heart failure and iron deficiency using cardiac magnetic resonance. Methods and Results Fifty‐three stable heart failure and iron deficiency patients were randomly assigned 1:1 to receive intravenous FCM or placebo in a multicenter, double‐blind study. T2* and T1 mapping cardiac magnetic resonance sequences, noninvasive surrogates of intramyocardial iron, were eval…

MaleCardiac magnetic resonance*ferric carboxymaltoseMagnetic Resonance Imaging (MRI)Myocardial ironAnèmia*heart failure030204 cardiovascular system & hematologyFerric Compounds0302 clinical medicine030212 general & internal medicineOriginal Researchcardiac magnetic resonance ferric carboxymaltose heart failure iron deficiency myocardial ironAnemia Iron-DeficiencyAnemiaIron deficiencyMiddle AgedMyocardial ironMagnetic Resonance Imaging*myocardial ironMagnetic resonanceCardiologyAdministration IntravenousFemaleCardiology and Cardiovascular Medicine*cardiac magnetic resonancemedicine.medical_specialtyNoninvasive imagingCardiomyopathyIronIntravenous ironHeart failureFERRIC CARBOXYMALTOSE03 medical and health sciencesDouble-Blind MethodInternal medicinemedicineHumansMaltoseAgedPharmacologybusiness.industryMyocardiumIron deficiencyRessonància magnèticaMiocardimedicine.diseaseFerric carboxymaltoseTreatmentHeart failureHematinicsbusinessCardiac magnetic resonance*iron deficiencyFerro
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Implicaciones pronósticas de la hipo e hiperpotasemia en la insuficiencia cardíaca aguda con fracción de eyección reducida. Análisis de la mortalidad…

2022

Resumen Antecedentes y objetivos Las alteraciones del potasio constituyen un problema clinico de gran magnitud en la insuficiencia cardiaca (IC) descompensada. Este estudio pretende valorar las implicaciones pronosticas de la hipo e hiperpotasemia al ingreso por IC aguda en la mortalidad cardiovascular y reingresos hospitalarios. Material y metodo De enero de 2016 a junio de 2020 fueron ingresados 1.397 casos con diagnostico de IC aguda. Se excluyeron ingresos programados para estudio, terapias electivas y pacientes con fraccion de eyeccion del ventriculo izquierdo  >  40%. El estudio se realizo sobre 689 pacientes, 45 con potasio (K+)   5,0 mmol/l y 595 K+  =  3,5-5,0 mmol/l. Se analizaron…

Gynecologymedicine.medical_specialtyEjection fractionbusiness.industryHeart failureMedicineGeneral Medicinebusinessmedicine.diseaseCardiovascular mortalityMedicina Clínica
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Impact of donor-recipient age on cardiac transplant survival. Subanalysis of the Spanish Heart Transplant Registry.

2020

[Abstract] Introduction and objectives. The age of heart transplant recipients and donors is progressively increasing. It is likely that not all donor-recipient age combinations have the same impact on mortality. The objective of this work was to compare survival in transplant recipients according to donor-recipient age combinations. Methods. We performed a retrospective analysis of transplants performed between 1 January 1993 and 31 December 2017 in the Spanish Heart Transplant Registry. Pediatric transplants, retransplants and combined transplants were excluded (6505 transplants included). Four groups were considered: a) donor < 50 years for recipient < 65 years; b) donor < 50 years for r…

medicine.medical_specialtyPrognostic factorTrasplante cardiacoMultivariate analysisSurvivalCombinaciones de edad de donante y receptor Donor age Donor/recipient age combinations Edad del donante Edad del receptor Heart transplant Recipient age Supervivencia Survival Trasplante cardiacoEnfermedad cardiovascularDonor/recipient age combinationsRecipient age030204 cardiovascular system & hematologyDonor age03 medical and health sciences0302 clinical medicineInternal medicineRetrospective analysisEdad del receptorMedicineHumansTrasplante de corazónRegistriesChildRetrospective StudiesSupervivenciabusiness.industryEdad del donanteGraft SurvivalAge FactorsCombinaciones de edad de donante y receptorGeneral MedicineTissue DonorsTransplant RecipientsTrasplante de órganosDatos estadísticosHeart TransplantationHeart transplantSupervivencia tisularbusinessMedian survival
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Epidemiological Study of Tricuspid Regurgitation After Cardiac Transplantation. Does it Influence Survival?

2022

Background: Tricuspid valve disease is the most frequent valvulopathy after heart transplantation (HTx). Evidence for the negative effect of post-transplant tricuspid regurgitation (TR) on survival is contradictory. The aim of this study was to analyze the causes of post-transplant TR and its effect on overall mortality.Methods: This is a retrospective observational study of all transplants performed in two Spanish centers (1009 patients) between 2000 and 2019. Of the total number of patients, 809 had no TR or mild TR and 200 had moderate or severe TR. The etiology of TR was analyzed in all cases.Results: The prevalence of moderate and severe TR was 19.8%. The risk of mortality was greater …

TransplantationSurvivalIncidenceTricuspid regurgitationHeart transplantationPrognosisSeverity of Illness IndexTricuspid Valve Insufficiency*aetiologyTreatment Outcome*heart transplantation*tricuspid regurgitation*prognosisHumansHeart Transplantation*survivalAetiologyRetrospective StudiesTransplant international : official journal of the European Society for Organ Transplantation
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Abstract 16304: Readiness for Physical Activity in Patients With Heart Failure

2020

Introduction: Little attention has been given to assessing the physical readiness and psychological readiness (motivation &amp; self-efficacy) in patients with heart failure (HF). The aim of this study is to explore the readiness for PA (physical and psychological) in patients with HF and factors related. Method: A cross-sectional study with 163 patients included (mean age 66±16, 50% female, 63% NYHA I, 37% NYHA II) assessing background and clinical data, physical activity (IPAQ-s), depression and anxiety (HADs), quality of life (SF36). Readiness for PA was assessed with physical readiness based on the PA Readiness Questionnaire (PAR-Q) and psychological readiness was measured with the Exe…

medicine.medical_specialtyRehabilitationbusiness.industrymedicine.medical_treatmentPhysical activitymedicine.diseasePhysiology (medical)Heart failurePhysical therapymedicineIn patientCardiology and Cardiovascular MedicinebusinessCardiovascular nursingCirculation
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Depression mediates physical activity readiness and physical activity in patients with heart failure.

2021

Aims Although physical activity (PA) and exercise are essential for patients with heart failure (HF), adherence to the recommended guidelines is low. Not much is known about the mediating effect of HF patients mental state with their readiness for PA and reported activity levels. The purpose of this study is to investigate the mediatory effect of depression on PA readiness (physical limitation and psychological readiness) and self-reported PA in patients with HF. Methods and results In this cross-sectional study, 163 New York Heart Association Class I and II HF patients, during their clinic visit, reported on their physical limitation (PAR-Q) and psychological readiness [self-efficacy (ESES…

medicine.medical_specialtyPhysical activityDiseases of the circulatory (Cardiovascular) systemMedicineHumansIn patientSjukgymnastikPhysiotherapyExerciseDepression (differential diagnoses)Heart failure; Depression; Physical activity; Readiness; Motivation; Self-efficacyNew York Heart Association Class ISelf-efficacyHeart FailureMotivationbusiness.industryDepressionPhysical activityDepression Heart failure Motivation Physical activity Readiness Self-efficacyOriginal Articlesmedicine.diseaseReadinessPhysical limitationsCross-Sectional StudiesRC666-701Mental stateHeart failurePhysical therapyOriginal ArticleSelf ReportCardiology and Cardiovascular MedicinebusinessSelf‐efficacyESC heart failure
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A New Mutation in the Ryanodine Receptor 2 Gene (RYR2 C2277R) as a Cause Catecholaminergic Polymorphic Ventricular Tachycardia

2015

GeneticsTachycardiabusiness.industryGeneral MedicineCatecholaminergic polymorphic ventricular tachycardiamedicine.diseaseRyanodine receptor 2Dna geneticsDNA Mutational AnalysisMutation (genetic algorithm)New mutationMedicinemedicine.symptombusinessGeneRevista Española de Cardiología (English Edition)
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