0000000000121465

AUTHOR

Ulrike Kottler

showing 9 related works from this author

Keratopathie als Zeichen einer multifokalen kongenitalen sensiblen Polyneuropathie

2001

Patient. Bei einer 63-jahrigen Patientin bestanden seit 10 Jahren beidseits rezidivierende korneale Ulzera mit Trubungen, Vaskularisation und aufgehobener Sensibilitat. Daneben fanden sich asymmetrisch angeordnete hypasthetische Areale. Sensible Nervenaktionspotenziale der betroffenen Regionen waren nicht ableitbar, sensorisch evozierte Potenziale fielen pathologisch aus, Muskeleigenreflexe waren ausgefallen. In der Suralisbiopsie zeigte sich ein hochgradiger Mangel an markhaltigen Axonen. Erworbene Polyneuropathieformen konnten ausgeschlossen werden. Therapie. Nach konservativen Therapieversuchen erfolgte wegen der vaskularisierten Hornhautnarbe eine perforierende Keratoplastik am linken A…

GynecologyOphthalmologymedicine.medical_specialtybusiness.industryMedicinebusinessDer Ophthalmologe
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Central corneal thickness in mucopolysaccharidosis II and VI.

2010

Objective To describe the ultrasonographically detected central corneal thickness (CCT) in patients with Type II and VI mucopolysaccharidosis (MPS) and its impact on applanation tonometry and glaucoma detection. Methods Twenty-eight patients with MPS (19 MPS II, nine MPS VI) underwent pachymetric investigation of CCT. Additionally, ultrasound measurements of axial length of the globe, slit-lamp evaluation with semiquantitative grading of corneal clouding, applanation tonometry, and assessment of refractive error were performed. Results Median average corneal thickness was 534.5 microm (range, 491.5-579.0 microm) in the MPS II and 547.0 microm (range, 492.5-693.05 microm) in the MPS VI group…

Applanation tonometryAdultMalecongenital hereditary and neonatal diseases and abnormalitiesRefractive errorIntraocular pressuremedicine.medical_specialtygenetic structuresAdolescentMucopolysaccharidosis IIMucopolysaccharidosisGlaucomaCorneal DiseasesCorneaTonometry OcularOphthalmologymedicineHumansIn patientProspective StudiesChildIntraocular PressureMucopolysaccharidosis IIUltrasonographyMucopolysaccharidosis VIAnthropometrybusiness.industryUltrasoundnutritional and metabolic diseasesGlaucomaMiddle Agedmedicine.diseaseeye diseasesOphthalmologyFemalesense organsbusinessCornea
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Prevalence of refractive errors in the European adult population: the Gutenberg Health Study (GHS).

2014

Objective To study the distribution of refractive errors among adults of European descent. Design Population-based eye study in Germany with15 010 participants aged 35–74 years. Methods The study participants underwent a detailed ophthalmic examination according to a standardised protocol. Refractive error was determined by an automatic refraction device (Humphrey HARK 599) without cycloplegia. Definitions for the analysis were myopia +0.5 D, astigmatism >0.5 cylinder D and anisometropia >1.0 D difference in the spherical equivalent between the eyes. Exclusion criterion was previous cataract or refractive surgery. Results 13 959 subjects were eligible. Refractive errors ranged from −21.5 to…

AdultMalemedicine.medical_specialtyRefractive errorgenetic structuresmedicine.medical_treatmentPopulationVisual AcuityAstigmatismWhite PeopleCellular and Molecular NeuroscienceAge DistributionRefractive surgeryOphthalmologyGermanymedicinePrevalenceHumansVision testProspective StudiesSex DistributioneducationRetinoscopyAnisometropiaAgededucation.field_of_studymedicine.diagnostic_testbusiness.industryVision TestsCycloplegiaMiddle Agedmedicine.diseaseRefractive ErrorsHealth Surveyseye diseasesSensory SystemsOphthalmologyOptometryFemalemedicine.symptombusinessRetinoscopyThe British journal of ophthalmology
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Mitomycin C bei oberflächlichen Hornhautablationen mit dem Excimer-Laser: Eigene Erfahrungen und Literaturübersicht

2005

Haze formation with loss of corneal transparency and surface irregularities and myopic regression are the major complications after corneal refractive surface surgery. The use of mitomycin C (MMC) with its antibiotic and antineoplastic properties is intended to inhibit wound healing mechanisms leading to subepithelial fibrosis. We report the use of MMC to achieve visual rehabilitation in the re-treatment of 3 eyes of 2 patients following refractive corneal surgery. According to the literature, the local use of MMC 0.02 % for 2 minutes is safe and enables one to treat and prevent stromal haze and myopic regression and allows a reduction of the postoperative topical pharmacotherapy. Results a…

medicine.medical_specialtygenetic structuresbusiness.industryMitomycin CVisual rehabilitationCorneal opacityeye diseasesCorneal transparencySurgeryOphthalmologyPharmacotherapyCorneal surgerySubepithelial fibrosisMedicinesense organsMajor complicationbusinessKlinische Monatsblätter für Augenheilkunde
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Effect of large positioning holes on capsule fixation of plate-haptic intraocular lenses

2000

Abstract Purpose To compare the centration and fixation of silicone plate-haptic intraocular lenses (IOLs) with different-sized positioning holes. Setting Eye Clinic of the Johannes Gutenberg-University Mainz, Mainz, Germany. Methods In a prospective randomized study, 51 Chiroflex C10 and 56 Chiroflex C11 IOLs were implanted under standardized conditions by the same surgeon. The IOL position was documented at the end of surgery and by retroillumination on the first day and 5 months postoperatively. The positioning-hole area was evaluated by ultrasound biomicroscopy (50 MHz) 5 months postoperatively. Results One day postoperatively, no IOL in either group was decentered more than 1.0 mm. Aft…

Malemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentEye diseaseLens Capsule CrystallineUltrasound biomicroscopyIntraocular lensProsthesis Designlaw.inventionFixation (surgical)Foreign-Body MigrationLens Implantation IntraocularlawOphthalmologyHumansMedicineProspective StudiesCapsulorhexisAgedUltrasonographyAged 80 and overLenses Intraocularbusiness.industrySuture TechniquesCapsuleMiddle Agedmedicine.diseaseCapsulorhexiseye diseasesSensory SystemsSurgeryLens (optics)OphthalmologyCapsulotomyFemaleSurgerysense organsbusinessCell DivisionJournal of Cataract and Refractive Surgery
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Impact of the line of sight on toric phakic intraocular lenses for hyperopia

2003

We present a hyperopic patient with a decentered line of sight in whom the residual refractive error after toric phakic intraocular lens (TP IOL) implantation was improved by displacement and individualized treatment. A 35-year-old woman presented with asthenopic complaints 2 months after bilateral TP IOL implantation and IOL rotation 4 weeks later. Examination revealed the line of sight to be nasally and inferiorly decentered in relation to the center of the pupil. A more nasal reenclavation of the TP IOL decreased the coma, and the uncorrected visual acuity was 20/20. We conclude that line of sight should be measured before TP IOL implantation, especially in hyperopic eyes.

AdultReoperationRefractive errormedicine.medical_specialtygenetic structuresEye diseasemedicine.medical_treatmentVision DisordersVisual AcuityComa (optics)Intraocular lensUncorrected visual acuityPhakic intraocular lensPupilVision disorderForeign-Body MigrationLens Implantation IntraocularOphthalmologyLens CrystallinemedicineHumansbusiness.industryAstigmatismCorneal TopographyPupilmedicine.diseaseeye diseasesSensory SystemsOphthalmologyHyperopiaOptometryFemaleSurgeryAsthenopiasense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
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Correlations between central corneal thickness and general anthropometric characteristics and cardiovascular parameters in a large European cohort fr…

2014

PURPOSE The aim of this study was to evaluate the correlations between general anthropometric features and cardiovascular parameters and central corneal thickness (CCT) in an adult European cohort. METHODS Analysis was based on a Gutenberg Health Study cohort that included 5000 subjects (2540 male, 2460 female), aged 35 to 74 years at enrollment. The participants underwent a standardized protocol with a comprehensive questionnaire; ophthalmic examination (slit-lamp biomicroscopy; autorefractometry; noncontact tonometry; fundus photography; CCT measurements (optical pachymetry); visual field testing; and a thorough general examination focused on cardiovascular parameters, psychosomatic evalu…

AdultMalemedicine.medical_specialtygenetic structuresCorneal PachymetryBody Mass IndexCorneaTonometry OcularSex FactorsRisk FactorsDiabetes mellitusOphthalmologySurveys and QuestionnairesMedicineHumansProspective StudiesCorneal pachymetryProspective cohort studyIntraocular PressureAgedmedicine.diagnostic_testAnthropometrybusiness.industryBody WeightFundus photographyAnthropometryMiddle Agedmedicine.diseaseeye diseasesOphthalmologyCardiovascular DiseasesCohortOptometryVisual Field TestsFemalesense organsbusinessBody mass indexDyslipidemiaCornea
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Komplikationen einer großen kongenitalen Ziliarkörperzyste

2002

Background Multiple cysts of iris and ciliary body may cause many complications such as acute or chronic angle closure glaucoma. Patient We present a boy with multiple congenital cysts of the iris pigment epithelium and a voluminous cyst of the unpigmented ciliary body epithelium of the right eye. This resulted in lenticular astigmatism, concomitant strabismus divergens and subsequently to anisometropia. The voluminous cyst (8 x 12 mm in diameter) was folded around the lens, reached the optic axis and resulted in displacement of the lens and contact between the iris and the corneal endothelium from 6.30 to 11. After puncture and partial resection of the cyst at the age of 8 months the boy d…

medicine.medical_specialtyVisual acuitygenetic structuresbusiness.industrymedicine.medical_treatmentVitrectomyCataract surgerymedicine.diseaseeye diseasesSurgeryOphthalmologyCiliary bodymedicine.anatomical_structureLens (anatomy)OphthalmologymedicineIris pigment epitheliumCystsense organsmedicine.symptomIris (anatomy)businessKlinische Monatsblätter für Augenheilkunde
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Distribution of Intraocular Pressure and Its Association with Ocular Features and Cardiovascular Risk Factors

2013

Purpose To describe the distribution of intraocular pressure (IOP) and its association with ocular features and cardiovascular risk factors in an adult European cohort. Design Population-based, cross-sectional study. Participants This analysis was based on a Gutenberg Health Study (GHS) cohort that included 4335 eligible enrollees from among 5000 subjects who participated in the survey from 2007 through 2008. The age range was 35 to 74 years at enrollment. Methods Participants underwent a standardized protocol with a comprehensive questionnaire; ophthalmic examination including slit-lamp biomicroscopy, noncontact tonometry, fundus photography, central corneal thickness measurement, and visu…

Intraocular pressuremedicine.medical_specialtyMultivariate analysisWaistgenetic structuresmedicine.diagnostic_testbusiness.industryFundus photographymedicine.diseaseeye diseasesOphthalmologyDiabetes mellitusOphthalmologyCohortMedicinesense organsbusinessBody mass indexDyslipidemiaOphthalmology
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