0000000000121548
AUTHOR
K. Birkenkamp
Multirotations-CT und ARDS
Purpose Aim of the study was to investigate alveolar inspiration and expiration using multiscan CT. Results of a visual assessment using a scoring system were compared with density ranges known to represent alveolar ventilation best. Method Pigs were examined before and after lavage-induced ARDS. All animals were examined using dynamic multiscan CT. The visual assessment was done by a scoring system proposed by Gattinoni. The results were compared with planimetric determination of defined density ranges. Results In the healthy lung, the visual analysis showed higher scores at lower airway pressures with a marked gradient, whereas at higher pressures neither opacities nor gradients were obse…
Multirotations-CT während kontinuierlicher Beatmung: Vergleich unterschiedlicher Dichtebereiche bei gesunden Lungen und im Lavage-ARDS Modell
PURPOSE In this animal study, density ranges for CT-based quantification of ventilated lung area were determined. Healthy lungs and ARDS lungs were compared during artificial respiration. MATERIAL AND METHODS CT-scans were performed in 5 anesthetized pigs using a dynamic multiscan CT option on a predefined transverse slice (slice thickness 1 mm; effective temporal resolution, 250 ms). During continuous CT acquisition, airway pressure was increased or decreased in a stepwise manner. In all images, areas of defined HU ranges were determined planimetrically. The lower threshold was set to -910 HE in all images. The upper threshold was varied from -800 HE to -200 HE in steps of 100 HE. RESULTS …