0000000000121829

AUTHOR

Serena Fanara

showing 17 related works from this author

Antimicrobial and antistaphylococcal biofilm activity from the sea urchin Paracentrotus lividus

2010

Aims:  Staphylococcal biofilm-associated infections are resistant to conventional antibiotics. Consequently, new agents are needed to treat them. With this aim, we focused on the effector cells (coelomocytes) of the sea urchin Paracentrotus lividus immune system. Methods and Results:  We tested the activity of the 5-kDa peptide fraction of the cytosol from coelomocytes (5-CC) against a group of Gram-positive, Gram-negative bacteria and fungi. We determined minimal inhibitory concentrations (MICs) ranging from 253·7 to 15·8 mg ml−1. We observed an inhibitory activity and antibiofilm properties of 5-CC against staphylococcal biofilms of reference strains Staphylococcus epidermidis DSM 3269 an…

biologymedicine.drug_classAntibioticsAntimicrobial peptidesBiofilmGeneral Medicinemedicine.disease_causebiology.organism_classificationAntimicrobialApplied Microbiology and BiotechnologyParacentrotus lividusMicrobiologyStaphylococcus aureusStaphylococcus epidermidismedicineBacteriaBiotechnologyJournal of Applied Microbiology
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Occurrence of illicit drugs in two wastewater treatment plants in the South of Italy

2017

In this study the occurrence and the behavior of illicit drugs and their metabolites have been investigated for two wastewater treatment plants (WWTPs) (namely, WWTP-1 and WWTP-2) located in Sicily (island of Italy). Samples were analyzed for methamphetamine, cocaine (COC), 3,4-methylenedioxymethamphetamine (MDMA), methadone (METH), 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), 3,4-methylenedioxy amphetamine (MDA); 3,4-methylenedioxy ethylamphetamine (MDEA), 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH) and Benzoylecgonine (BEG). The BEG, COC, MOR and THC-COOH were found at the highest concentration in both WWTPs. The Wastewater-based epidemiology calculation for BEG, COC…

PyrrolidinesHealth Toxicology and Mutagenesis0208 environmental biotechnology02 engineering and technologyWastewater010501 environmental sciencesSettore MED/42 - Igiene Generale E ApplicataWaste Disposal Fluid01 natural sciencesMethamphetamineIllicit drugchemistry.chemical_compoundCocaineSettore BIO/10 - BiochimicaCannabidiolWater treatmentDronabinolSicilyDrug behavioreducation.field_of_studybiologyTraditional medicineChemistry (all)MDMAGeneral MedicineMethamphetaminePollutionContaminants of emerging concernSubstance Abuse DetectionDrug CombinationsBenzoylecgoninemedicine.drugEnvironmental EngineeringPopulationmedicineHumansEnvironmental Chemistryeducation0105 earth and related environmental sciencesSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleIllicit Drugsbusiness.industryAmphetaminesCodeinePublic Health Environmental and Occupational HealthGeneral Chemistrybiology.organism_classificationEthylamphetamine020801 environmental engineeringAmphetaminechemistryCannabisbusinessWater Pollutants ChemicalMethadoneChemosphere
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Effetto del PRD (Partial Rootzone Drying)sulla composizione della frazione volatile di mele ‘Pink Lady’

2008

Settore CHIM/10 - Chimica Degli Alimentimele
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Mucoadhesive Solid Lipid Microparticles (SLM) for sustained release of corticosteroids to the lungs

2016

Pulmonary delivery is the preferred route of drug administration in the treatment of many respiratory disease, such as asthma and chronic obstructive pulmonary disease (COPD). Over the years, several kinds of carriers have been studied for sustained release of corticosteroids and bronchodilators to the lungs. Solid Lipid Microparticles (SLM) due to their biocompatibility and size (3-5 µm) can reach the bronchial epithelium directly, circumvent first pass metabolism and avoid systemic toxicity [1,2]. In this work we describe the preparation and the characterization of two different systems subjected to chitosan and alginate coating for sustained release of fluticasone propionate (FP) into th…

DRUG DELIVERYMICROPARTICLESFLUTICASONE PROPIONATE BPCOLUNGmicroparticles lung delivery corticosteroids BPCO
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Orientation and molecular contacts of melatonin confined into AOT and lecithin reversed micellar systems

2008

Abstract The state of increasing amounts of melatonin (MLT) confined in dry AOT or lecithin reversed micelles dispersed in CCl 4 has been investigated by UV–vis and 1 H NMR spectroscopies. The experimental results are consistent with MLT totally entrapped in reversed micelles, as a consequence of specific melatonin/surfactant interaction; the main driving force of the MLT solubilization in the core of reversed micelles is the establishment of H-bonding between the MLT NH groups (both indolic and amidic) and the head group of surfactants. The short contacts deduced from intermolecular NOEs are accounted for by favourable interactions between the surfactant's polar head and the H7–NH–H2 fragm…

food.ingredientIntermolecular forceReversed micelleLecithinNuclear Overhauser enhancementPhotochemistryLecithinMicelleMelatoninchemistry.chemical_compoundconfinement melatonin reverse micellesColloid and Surface ChemistryfoodchemistryPulmonary surfactantPhosphatidylcholineProton NMRmedicineOrganic chemistryMoleculeAOTMelatoninmedicine.drug
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ESI/MS study of singly charged clusters formed by bis-(ethylhexyl)sulfosuccinate (AOT-) and Fe 3+

2007

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Self Assembling di tensioattivi in fase gassosa: ESI/MS di aggregati a sigola carica di Yb(AOT)3

2006

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Analisi ambientale: determinazione di IPA, pesticidi e acrilammide in bacini idrogeologici della regione sicilia

2007

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Aroma compounds in sicilian olive oils from three cultivars at different ripening stages

2007

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Partitioning study of polyciclic aromatic hydrocarbons between water and water insoluble phases

2006

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Idrocarburi policiclici aromatici: studi di ripartizione tra acqua e sistemi complessi per la ricerca di nuove metodiche analitiche

2006

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Analysis of furan in coffee of different provenance by head-space solid phase microextraction gas chromatography-mass spectrometry: effect of brewing…

2009

A simple, sensitive and accurate method for the analysis of furan in roasted coffee has been used based on headspace-solid-phase micro-extraction (HS-SPME) coupled to gas chromatography-mass spectrometry (GC-MS). The extraction was performed using 75-microm carboxen/polydimethylsiloxane fiber. Ionic strength, extraction time and temperature, and desorption time were assessed as the most important parameters affecting the HS-SPME procedure and d(4)-furan was used as the internal standard. The linearity range was in the range 0.0075-0.486 ng g(-1); the LOD and LOQ calculated using the signal-to-noise ratio approach were 0.002 and 0.006 ng g(-1), respectively. The inter- and intra-day precisio…

Hot TemperatureSettore CHIM/10 - Chimica Degli AlimentiFood HandlingfuranHealth Toxicology and MutagenesisAnalytical chemistryFood ContaminationToxicologyMass spectrometrySolid-phase microextractionCoffeeGas Chromatography-Mass SpectrometryBeverageschemistry.chemical_compoundbrewing procedures; coffee; furan; SPME-GC/MSFuranFuransSolid Phase MicroextractionSPME-GC/MSChromatographybusiness.industryExtraction (chemistry)Public Health Environmental and Occupational HealthGeneral ChemistryGeneral MedicinechemistryIonic strengthCarcinogensbrewing procedureBrewingGas chromatographyGas chromatography–mass spectrometrybusinessFood ScienceFood additivescontaminants. Part A, Chemistry, analysis, control, exposurerisk assessment
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Partitioning study of polycyclic aromatic hydrocarbons between water and some selected water-insoluble phases

2007

An investigation on the partitioning of naphthalene and phenanthrene between water and some water-insoluble phases has been carried out by Uv-vis-NIR spectrophotometry. The analysis of the experimental results emphasized the role of intermolecular interactions and structural features of the hosting phases as driving forces of the partitioning of these polycyclic aromatic hydrocarbons. The critical comparison of the resulting distribution constants allowed to evaluate the potentials of some extracting phases to set up sensitive analytical methods and/or effective environment remediation technologies.

DNA-ADDUCTSEXTRACTIONSpectroscopy Near-Infraredmedicine.diagnostic_testEnvironmental remediationChemistryMUTATIONSIntermolecular forcetechnology industry and agricultureWaterWater insolublePhenanthreneSensitivity and SpecificityAnalytical Chemistrychemistry.chemical_compoundSolubilityEnvironmental chemistrySpectrophotometrySOLUBILIZATIONmedicinePolycyclic CompoundsSpectrophotometry UltravioletGeneral Environmental ScienceNaphthalene
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FT-IR investigation of the state of iron (III) chloride clusters confined in AOT reverse micelles dispersed in carbon tetrachloride

2007

The state of the water-soluble salt iron(III) chloride in AOT reverse micelles dispersed in carbon tetrachloride has been investigated by FT-IR spectroscopy. Interestingly, while the entrapment of a lot of water-soluble inorganic salts in AOT reverse micelles requires preliminarily the presence of significant amounts of water within the micellar core, solubilization of FeCl3 occurs without the need to add water in the micellar solution reaching the very high solubility value, expressed as the maximum salt-to-surfactant molar ratio, of 1.30. The analysis of the spectral features of the investigated samples leads to hypothesize that iron(III) chloride is confined within the reverse micellar c…

chemistry.chemical_classificationChemistryInorganic chemistryIonic bondingGeneral ChemistryConductivityCondensed Matter PhysicsBiochemistryChlorideMicelleCrystallographychemistry.chemical_compoundmedicineGeneral Materials ScienceSolubilization Confinement effects Ferric chloride AOT reverse micelles Ionic clustersCounterionSolubilitySpectroscopyIron(III) chloridemedicine.drug
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Analysis of furan in toasted coffee by HS/SPME-GC-MS

2008

Furan coffeeHS/SPME-GC-MSSettore CHIM/10 - Chimica Degli Alimenti
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Studi di macroaggregati a singola carica in fase gassosa: AOT in presenza di ioni sodio e itterbio

2008

complessi non covalenti self assembling itterbio
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Fruit quality evolution of different olive table cultivars during fermentation.

2008

Settore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeLactic fermentation Sensory profile Nocellara del belice
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