0000000000125689

AUTHOR

Filippo Maria Salvini

showing 3 related works from this author

Factors Associated With Severe Gastrointestinal Diagnoses in Children With SARS-CoV-2 Infection or Multisystem Inflammatory Syndrome

2021

Key Points Question Is COVID-19 associated with severe gastrointestinal manifestations in children? Findings In this multicenter cohort study of 685 Italian children with COVID-19, 10% showed severe gastrointestinal involvement characterized by diffuse adeno-mesenteritis, appendicitis, abdominal fluid collection, ileal intussusception, or pancreatitis. Children older than 5 years and those presenting with abdominal pain, leukopenia, or receiving a diagnosis of multisystem inflammatory syndrome were more likely to have severe gastrointestinal manifestations. Meaning Severe gastrointestinal involvement is not uncommon in children with COVID-19, and awareness about its frequency and presentati…

MaleGastrointestinalPrognosiGastrointestinal DiseasesGastrointestinal DiseaseMultisystem Inflammatory SyndromeCOVID-19; Child; Child Preschool; Female; Gastrointestinal Diseases; Humans; Male; Prognosis; Radiography; Retrospective Studies; SARS-CoV-2; Systemic Inflammatory Response Syndromemacromolecular substancesSarsCoV2PediatricsRetrospective StudieHumansChildPreschoolChildrenOriginal InvestigationRetrospective StudiesSARS-CoV-2ResearchGastrointestinal Children SARS-CoV-2 Multisystem Inflammatory SyndromeCOVID-19General MedicinePrognosisSettore MED/38gastrointestinalSystemic Inflammatory Response SyndromeRadiographyOnline OnlyChild PreschoolFemaleSarsCoV2; COVID-19; gastrointestinalHuman
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Epidemiology, Clinical Features and Prognostic Factors of Pediatric SARS-CoV-2 Infection: Results From an Italian Multicenter Study

2021

Background: Many aspects of SARS-CoV-2 infection in children and adolescents remain unclear and optimal treatment is debated. The objective of our study was to investigate epidemiological, clinical and therapeutic characteristics of pediatric SARS-CoV-2 infection, focusing on risk factors for complicated and critical disease.Methods: The present multicenter Italian study was promoted by the Italian Society of Pediatric Infectious Diseases, involving both pediatric hospitals and general pediatricians/family doctors. All subjects under 18 years of age with documented SARS-CoV-2 infection and referred to the coordinating center were enrolled from March 2020.Results: As of 15 September 2020, 75…

Pediatricsmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MIS-CDisease030204 cardiovascular system & hematologyPediatrics03 medical and health sciences0302 clinical medicinechildren030225 pediatricsEpidemiologymedicinebookOriginal Researchmultisystem inflammatory syndromeMIS-C COVID-19business.industrySARS-CoV-2 infectionDisease progressionlcsh:RJ1-570COVID-19lcsh:PediatricsSettore MED/38Icu admissionCOVID-19; MIS-C; SARS-CoV-2 infection; children; multisystem inflammatory syndromeMulticenter studyPediatrics Perinatology and Child HealthPediatric Infectious Diseasebook.journalbusiness
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Severe Gastrointestinal Features in Children with COVID-19: A Multicenter Retrospective Cohort Study

2021

Background: Severe gastrointestinal (GI) involvement has been occasionally reported in children with SARS-CoV-2 infection or among those with multisystem inflammatory syndrome (MIS-C). We aimed to investigate the clinical, radiological and histopathological GI characteristics in order to identify factors associated with severe outcome. Methods: In this multicenter retrospective nationwide cohort study, symptomatic children with laboratory confirmed SARS-CoV-2 infection or MIS-C were enrolled. Children who received a diagnosis of acute abdomen, appendicitis, intussusception, pancreatitis, diffuse adeno-mesenteritis or abdominal fluid collections requiring surgical consultation and temporally…

Abdominal painPediatricsmedicine.medical_specialtybusiness.industryRetrospective cohort studyOdds ratiomedicine.diseaseAppendicitisAcute abdomenIntensive careMedicinePancreatitismedicine.symptombusinessCohort studySSRN Electronic Journal
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