0000000000132192

AUTHOR

Fabrice Lambert

showing 2 related works from this author

Dehydroepiandrosterone Induction of the Abcd2 and Abcd3 Genes encoding peroxisomal ABC Transporters

2003

Dehydroepiandrosterone (DHEA) is a peroxisome proliferator known to increase the expression of the genes encoding the peroxisomal s-oxidation enzymes in rodents. Using RT-PCR, we analysed the expression of the Abcd2 and Abcd3 genes encoding the peroxisomal ABC transporters ALDRP (ALD related protein) and PMP70 (70 kDa peroxisomal membrane protein) in primary cultures of rats hepatocytes treated with sulfated DHEA. We observed a time (12-72h) and dose (125-500μM) dependent increase in the expression of both genes.

chemistry.chemical_classificationSulfationEnzymeBiochemistrybiologychemistryABCD3ABCD2biology.proteinDehydroepiandrosteroneATP-binding cassette transporterPeroxisomeGene
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Anthropogenic Perturbations to the Atmospheric Molybdenum Cycle

2021

Molybdenum (Mo) is a key cofactor in enzymes used for nitrogen (N) fixation and nitrate reduction, and the low availability of Mo can constrain N inputs, affecting ecosystem productivity. Natural atmospheric Mo aerosolization and deposition from sources such as desert dust, sea‐salt spray, and volcanoes can affect ecosystem function across long timescales, but anthropogenic activities such as combustion, motor vehicles, and agricultural dust have accelerated the natural Mo cycle. Here we combined a synthesis of global atmospheric concentration observations and modeling to identify and estimate anthropogenic sources of atmospheric Mo. To project the impact of atmospheric Mo on terrestrial ec…

Atmospheric ScienceGlobal and Planetary ChangeNitrogenasechemistry.chemical_elementParticulatesAerosol depositionchemistryNitrogen fixationMolybdenumEnvironmental chemistryNutrient limitationNitrogenaseNitrogen fixationEnvironmental ChemistryEnvironmental scienceAerosol depositionParticulate matterGeneral Environmental Science
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