0000000000140955
AUTHOR
Jesús Millán Núñez-cortés
Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network
ABSTRACTBackgroundSpain has been one of the countries most affected by the COVID-19 pandemic.ObjectiveTo create a registry of patients with COVID-19 hospitalized in Spain in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease.MethodsA multicentre retrospective cohort study, including consecutive patients hospitalized with confirmed COVID-19 throughout Spain. Epidemiological and clinical data, additional tests at admission and at seven days, treatments administered, and progress at 30 days of hospitalization were collected from electronic medical records.ResultsUp to April 30th 2020, 6,424 patients from 109 hospitals were included. …
Consenso de expertos sobre propuestas para la mejora del manejo de la dislipemia aterogénica
Resumen Introduccion y objetivos La dislipemia aterogenica es un reconocido factor de riesgo cardiovascular; sin embargo, en la practica clinica frecuentemente se subestima y, en consecuencia, esta infratratada e infracontrolada. El objetivo es desarrollar un consenso multidisciplinario para establecer recomendaciones clinicas en torno a la dislipemia aterogenica para optimizar la prevencion, la deteccion precoz, la valoracion diagnostica, el abordaje terapeutico y el seguimiento. Metodos Tras la revision de las evidencias cientificas, el comite cientifico formulo 87 recomendaciones relacionadas con la dislipemia aterogenica, agrupadas en cinco areas: conceptos generales (10 items), impacto…
The REALIST (REsiduAl risk, LIpids and Standard Therapies) study: an analysis of residual risk attributable to lipid profile in acute coronary syndrome
The R3i Foundation (Residual Risk Reduction Initiative), an independent, multinational and academic organization, is conducting the REALIST (Residual Risk, Lipids and Standard Therapies) study in 40 centers in different countries. This is a retrospective epidemiological study, designed to provide new data on the residual risk of major coronary events attributable to lipid abnormalities in patients receiving the current standard treatment. The initial results are expected in mid 2010, and the overall results at the end of 2010.
Predicting critical illness on initial diagnosis of COVID-19 based on easily-obtained clinical variables: Development and validation of the PRIORITY model
ABSTRACTObjectivesCurrently available COVID-19 prognostic models have focused on laboratory and radiological data obtained following admission. However, these tests are not available on initial assessment or in resource-limited settings. We aim to develop and validate a prediction model, based on clinical history and examination findings on initial diagnosis of COVID-19, to identify patients at risk of critical outcomes.MethodsWe used data from the SEMI-COVID-19 Registry, a nationwide multicenter cohort of consecutive patients hospitalized for COVID-19 from 132 centers in Spain. Clinical signs and symptoms, demographic variables, and medical history ascertained at hospital admission were sc…
Consenso Delphi sobre el diagnóstico y manejo de la dislipidemia en pacientes con enfermedad renal crónica: análisis post-hoc del estudio DIANA
Resumen Antecedentes y objetivos: Este estudio post hoc analizó la percepción de la importancia de la enfermedad renal crónica (ERC) en el cribado de la dislipidemia y en la elección del tratamiento con estatinas entre médicos de Atención Primaria (MAP) y otras especialidades mediante cuestionario Delphi. Métodos: El cuestionario incluyó 4 bloques de preguntas alrededor del paciente dislipémico con alteración del metabolismo hidrocarbonado. Aquí se presentan los resultados relacionados con la consideración de la ERC en el cribado y la elección de la estatina. Resultados: De los 497 expertos incluidos, el 58% eran MAP y el 42%, especialistas (35, el 7%, nefrólogos). Hubo consenso en realizar…
Estudio REALIST (REsiduAl risk, LIpids and Standard Therapies): Un análisis del Riesgo Residual dependiente del perfil lipídico en el síndrome coronario agudo
La Fundacion R3i (Residual Risk Reduction initiative), una organizacion academica, multinacional e independiente, esta llevando a cabo el estudio REALIST (REsidual risk, LIpids and Standard Therapies) en mas de 40 centros de diferentes paises. Se trata de un estudio epidemiologico retrospectivo, que esta disenado para proporcionar nuevos datos referentes al riesgo residual de episodios coronarios mayores atribuible a las alteraciones lipidicas en pacientes que reciben los tratamientos de referencia actuales. Sus resultados iniciales se esperan para mediados del ano 2010, y los resultados globales para finales del ano 2010.
Consenso Delphi sobre el diagnóstico y manejo de la dislipidemia en pacientes con enfermedad renal crónica: análisis post-hoc del estudio DIANA
ResumenAntecedentes y objetivosEste estudio post hoc analizó la percepción de la importancia de la enfermedad renal crónica (ERC) en el cribado de la dislipidemia y en la elección del tratamiento con estatinas entre médicos de Atención Primaria (MAP) y otras especialidades mediante cuestionario Delphi.MétodosEl cuestionario incluyó 4bloques de preguntas alrededor del paciente dislipémico con alteración del metabolismo hidrocarbonado. Aquí se presentan los resultados relacionados con la consideración de la ERC en el cribado y la elección de la estatina.ResultadosDe los 497 expertos incluidos, el 58% eran MAP y el 42%, especialistas (35, el 7%, nefrólogos). Hubo consenso en realizar un cribad…
Use of Expert Consensus to Improve Atherogenic Dyslipidemia Management
Abstract Introduction and objectives Although atherogenic dyslipidemia is a recognized cardiovascular risk factor, it is often underassessed and thus undertreated and poorly controlled in clinical practice. The objective of this study was to reach a multidisciplinary consensus for the establishment of a set of clinical recommendations on atherogenic dyslipidemia to optimize its prevention, early detection, diagnostic evaluation, therapeutic approach, and follow-up. Methods After a review of the scientific evidence, a scientific committee formulated 87 recommendations related to atherogenic dyslipidemia, which were grouped into 5 subject areas: general concepts (10 items), impact and epidemi…
Atherogenic Ratios in Patients with Recurrent Acute Coronary Syndrome and Receiving Statin Therapy: Clinical Usefullness as Cardiovascular Predictors
Patients who have already suffered a vascular event require more and better control of cardiovascular risk factors. Different atherogenic indexes such as TC/HDLc, LDLc/HDLc, apoB/apoA-I, LDLc/apoB and non-HDLc/HDLc have been used to follow-up the patients because of their predictive capacity of the lipid profile. The aim of this study was to evaluate atherogenic ratios as a marker of the lipid residual risk in high-risk patients receiving statin therapy and to know the changes produced by previous lipid-lowering drugs treatment for a previous coronary event. The study including patients admitted to coronary care units of six Spanish tertiary hospitals for Acute Coronary Syndrome (ACS). A to…
Documento Abordaje de la dislipidemia. Sociedad Española de Arteriosclerosis (parte III)
Unidad de Riesgo Cardiovascular y Lipidos, Departamento de Medicina Interna, Hospital General Universitario Gregorio aranon, Universidad Complutense, Madrid, Espana Servicio de Cardiologia, Clinica Universitaria de Pamplona, Universidad de Navarra, Pamplona, Espana Unidad de Lipidos, Servicio de Medicina Interna, Hospital Clinico, Universidad de Valencia, Valencia, Espana Unidad de Lipidos, Servicio de Medicina Interna, Hospital Carlos III, Madrid, Espana Miembro del grupo de Lipidos de SEMFYC, Centro de Salud Prosperidad, Madrid, Espana Unidad de Lipidos, Servicio de Medicina Interna, Hospital del Mar, Universidad Autonoma, Barcelona, Espana Unidad de Lipidos, Servicio de Medicina Interna,…