0000000000143589

AUTHOR

Minna Kellomäki

0000-0003-4321-1820

showing 3 related works from this author

Fractal-like Hierarchical CuO Nano/Microstructures for Large-Surface-to-Volume-Ratio Dip Catalysts

2022

Dip catalysts are attracting interest in both academia and industry for catalyzing important chemical reactions. These provide excellent stability, better recoverability, recyclability, and easy scale-up. Using the unique microstructures of leaf skeletons, we present a fractal-like hierarchical surface that can be used as a versatile and efficient dip catalyst. Copper oxide microcactuses with nanoscalar features were fabricated onto the Bauhinia racemosa leaf skeletons via a combination of physical vapor deposition, electroplating, and chemical oxidation methods. The coated leaf skeletons have a very high surface area, and the three-dimensional (3D) morphology allows the reactants to encoun…

mikrorakenteetalcohol dehydrogenationkatalyytitnanorakenteetbioinspiration216 Materials engineering221 Nanotechnologyleaf skeletondip catalystGeneral Materials Sciencekupari217 Medical engineeringcopper oxide
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Bioactive glass ions as strong enhancers of osteogenic differentiation in human adipose stem cells.

2015

Bioactive glasses are known for their ability to induce osteogenic differentiation of stem cells. To elucidate the mechanism of the osteoinductivity in more detail, we studied whether ionic extracts prepared from a commercial glass S53P4 and from three experimental glasses (2-06, 1-06 and 3-06) are alone sufficient to induce osteogenic differentiation of human adipose stem cells. Cells were cultured using basic medium or osteogenic medium as extract basis. Our results indicate that cells stay viable in all the glass extracts for the whole culturing period, 14 days. At 14 days the mineralization in osteogenic medium extracts was excessive compared to the control. Parallel to the increased mi…

MineralizationMaterials scienceBiomedical EngineeringAdipose tissuechemistry.chemical_elementBiocompatible MaterialsCalciumta3111BiochemistryBone tissue engineeringlaw.inventionBiomaterialsExtracellular matrixlawOsteogenic differentiationHumansBioactive glassMolecular Biologyta217Mesenchymal stem cellCell ProliferationIonsStem CellsMesenchymal stem cellta1182Cell DifferentiationGeneral MedicineIn vitroCell biologychemistryAdipose TissueBioactive glassAlkaline phosphataseGlassStem cellBiotechnologyBiomedical engineeringActa biomaterialia
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Bioactive glass ions induce efficient osteogenic differentiation of human adipose stem cells encapsulated in gellan gum and collagen type I hydrogels

2019

Abstract Background Due to unmet need for bone augmentation, our aim was to promote osteogenic differentiation of human adipose stem cells (hASCs) encapsulated in gellan gum (GG) or collagen type I (COL) hydrogels with bioactive glass (experimental glass 2-06 of composition [wt-%]: Na2O 12.1, K2O 14.0, CaO 19.8, P2O5 2.5, B2O3 1.6, SiO2 50.0) extract based osteogenic medium (BaG OM) for bone construct development. GG hydrogels were crosslinked with spermidine (GG-SPD) or BaG extract (GG-BaG). Methods Mechanical properties of cell-free GG-SPD, GG-BaG, and COL hydrogels were tested in osteogenic medium (OM) or BaG OM at 0, 14, and 21 d. Hydrogel embedded hASCs were cultured in OM or BaG OM fo…

SerumAdipose stem cellCompressive StrengthAdipose tissueCell Count02 engineering and technologySpectrum Analysis Raman01 natural sciencesMineralization (biology)Hydrogel Polyethylene Glycol Dimethacrylatelaw.inventionchemistry.chemical_compoundOsteogenesislawOsteogenic differentiationBioactive glassMineralsTissue ScaffoldsbiologyStem CellsPolysaccharides Bacterialbioactive glassCell DifferentiationMiddle Aged021001 nanoscience & nanotechnologyGellan gumCross-Linking ReagentsAdipose TissueMechanics of MaterialsBioactive glassSelf-healing hydrogelsOsteocalcinFemaleStem cellimplantit0210 nano-technologyMaterials scienceCell SurvivalOsteocalcinosteogenic differentiationchemistry.chemical_elementBioengineeringmacromolecular substancesCalciumta3111010402 general chemistryCollagen Type ICollagen type I hydrogelBiokemia solu- ja molekyylibiologia - Biochemistry cell and molecular biologylasiBiomaterialsCalcification Physiologicbiologinen aktiivisuusgellan gum hydrogelAnimalsHumansta217Ionsgeelitta1182adipose stem cellkantasolutRats0104 chemical sciencesDurapatiteGene Expression RegulationchemistryBiophysicsbiology.proteinGlassGellan gum hydrogelluukudoksetcollagen type I hydrogelBiomarkersMaterials Science and Engineering: C
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