0000000000147297

AUTHOR

Christoph Hintermüller

0000-0002-9132-4216

showing 2 related works from this author

Natural gas hydrate investigations by synchrotron radiation X-ray cryo-tomographic microscopy (SRXCTM)

2008

[1] We report the 3D microstructure analyses of natural gas hydrates sampled from Gulf of Mexico. The samples were characterized by synchrotron radiation X-ray cryo-tomographic microscopy (SRXCTM) using the ‘TOMCAT’ beam line at the Swiss Light Source (SLS). The SRXCTM demonstrates its applicability to unlock some microscopic features of the marine hydrates, in particular of crystallite size and grain boundary network. The gas hydrate domains are surrounded by a network of pores of typically a few micrometers, which are largely due to decomposition. Out of the SRXCTM data, the porosity, total volume of the voids, the void surface area and number of the total gas-filled voids have been calcu…

010504 meteorology & atmospheric sciencesbusiness.industryClathrate hydrateSynchrotron radiationMineralogy010502 geochemistry & geophysics01 natural sciencesGeophysicsNatural gasGeneral Earth and Planetary SciencesGrain boundaryCrystallitePorositybusinessHydrateGeologySwiss Light Source0105 earth and related environmental sciencesGeophysical Research Letters
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Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain

2021

The formation of new blood vessels and the establishment of vascular networks are crucial during brain development, in the adult healthy brain, as well as in various diseases of the central nervous system. Here, we describe a step-by-step protocol for our recently developed method that enables hierarchical imaging and computational analysis of vascular networks in postnatal and adult mouse brains. The different stages of the procedure include resin-based vascular corrosion casting, scanning electron microscopy, synchrotron radiation and desktop microcomputed tomography imaging, and computational network analysis. Combining these methods enables detailed visualization and quantification of t…

Vessel networkBiochemistry & Molecular BiologyBrain developmentBrain vasculatureScanning electron microscopeComputer sciencePoint densityCentral nervous systemVascular volumeGenetics and Molecular BiologyINTUSSUSCEPTIVE ANGIOGENESISINHIBITS TUMOR-GROWTHTortuosityBiochemical Research MethodsSCANNING-ELECTRON-MICROSCOPYGeneral Biochemistry Genetics and Molecular BiologyBLOOD-VESSELSSPROUTING ANGIOGENESIS10180 Clinic for NeurosurgeryNEUROVASCULAR UNIT1300 General Biochemistry Genetics and Molecular Biologymedicine10237 Institute of Biomedical EngineeringComputational analysisAdult stageMICROVASCULAR NETWORKSIntussusceptive angiogenesisSprouting angiogenesisScience & TechnologySTRUCTURAL ADAPTATIONCOCHLEAR VASCULATUREMOLECULAR-MECHANISMS10177 Dermatology Clinic10081 Institute of Veterinary Physiology10124 Institute of Molecular Life SciencesVessel diametermedicine.anatomical_structureVascular network10036 Medical ClinicGeneral Biochemistry570 Life sciences; biologyLife Sciences & BiomedicinePerfusionBiomedical engineering
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