A multispectral imaging approach for diagnostics of skin pathologies
Noninvasive multispectral imaging method was applied for different skin pathology such as nevus, basal cell carcinoma, and melanoma diagnostics. Developed melanoma diagnostic parameter, using three spectral bands (540 nm, 650 nm and 950 nm), was calculated for nevus, melanoma and basal cell carcinoma. Simple multispectral diagnostic device was established and applied for skin assessment. Development and application of multispectral diagnostics method described further in this article.
Skin cancer screening – better safe than sorry
Skin cancer is the most common type of cancers. In Latvia, on average there are approximately 200 new melanoma and 1300 non-melanoma cancer cases per year. Non-melanoma cancers are: Basal Cell Carcinoma, Squamous Cell Carcinoma and others. It is essential to discover skin cancer at an early stage when it is treatable. For this reason, a reliable, non-invasive and quantitative skin cancer screening method is necessary in order to discover skin cancer as early as possible and to help physicians such as general practitioners and dermatologists assign patients to the best treatment as soon as possible. In this article, the current skin cancer incidence as well as the screening situation in Latv…
Spectral imaging as a tool for the evaluation of skin cancer post-operative scars
Skin cancer is the most common type of cancer in the USA and worldwide.1 An early diagnosis is the key to a successful treatment. Among the skin cancers, the malignant melanoma (MM) accounts for 1% of the cases while it is responsible for the majority of deaths. Basal cell carcinoma (BCC) is the most common form of skin cancer with a very low mortality rate.2 Unfortunately, skin cancer recurrence is a common problem for MM and BCC patients. We propose a post-operative scar screening with non-invasive autofluorescence (AF) imaging to detect an early growth of any residual tissue from the cancer removal procedure. The screening images can serve also as a visual evidence for the post-op patien…
Imaging of LED-excited autofluorescence photobleaching rates for skin diagnostics
The aim of this study is to develop a novel non-invasive approach for skin cancer (melanoma, basal cell and squamous cell carcinomas) diagnostics by mapping the AF intensity decrease (photo-bleaching) rates under continuous 405 nm LED excitation. For parametric mapping of skin AF intensity decrease rates a sequence of filtered AF imaging under 405 nm LED excitation for 20 seconds at a power density of ~7 mW/cm2 with a frame rate 0.5 fps was recorded and analyzed by cloud-based prototype device. Several clinical cases and potential future applications of the proposed autofluorescence photobleaching rate imaging technique are discussed.
Autofluorescence imaging for recurrence detection in skin cancer postoperative scars
This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to r…
Non-invasive LED-based screening solution for skin cancer
Skin cancer is the most common type of malignant tumors in humans. Early diagnosis is the key to successful surgical treatment. In this work we present a non-invasive screening tool for early stage detection of skin cancer and also for the evaluation of post-operative scars.