Spectral entropy based neuronal network synchronization analysis based on microelectrode array measurements

Synchrony and asynchrony are essential aspects of the functioning of interconnected neuronal cells and networks. New information on neuronal synchronization can be expected to aid in understanding these systems. Synchronization provides insight in the functional connectivity and the spatial distribution of the information processing in the networks. Synchronization is generally studied with time domain analysis of neuronal events, or using direct frequency spectrum analysis, e.g., in specific frequency bands. However, these methods have their pitfalls. Thus, we have previously proposed a method to analyze temporal changes in the complexity of the frequency of signals originating from differ…

On the regularity of very weak solutions for linear elliptic equations in divergence form

AbstractIn this paper we consider a linear elliptic equation in divergence form $$\begin{aligned} \sum _{i,j}D_j(a_{ij}(x)D_i u )=0 \quad \hbox {in } \Omega . \end{aligned}$$ ∑ i , j D j ( a ij ( x ) D i u ) = 0 in Ω . Assuming the coefficients $$a_{ij}$$ a ij in $$W^{1,n}(\Omega )$$ W 1 , n ( Ω ) with a modulus of continuity satisfying a certain Dini-type continuity condition, we prove that any very weak solution $$u\in L^{n'}_\mathrm{loc}(\Omega )$$ u ∈ L loc n ′ ( Ω ) of (0.1) is actually a weak solution in $$W^{1,2}_\mathrm{loc}(\Omega )$$ W loc 1 , 2 ( Ω ) .

Quasi-linear parabolic equations with degenerate coercivity having a quadratic gradient term

We study existence and regularity of distributional solutions for possibly degenerate quasi-linear parabolic problems having a first order term which grows quadratically in the gradient. The model problem we refer to is the following (1){ut−div(α(u)∇u)=β(u)|∇u|2+f(x,t),in Ω×]0,T[;u(x,t)=0,on ∂Ω×]0,T[;u(x,0)=u0(x),in Ω. Here Ω is a bounded open set in RN, T>0. The unknown function u=u(x,t) depends on x∈Ω and t∈]0,T[. The symbol ∇u denotes the gradient of u with respect to x. The real functions α, β are continuous; moreover α is positive, bounded and may vanish at ±∞. As far as the data are concerned, we require the following assumptions: ∫ΩΦ(u0(x))dx<∞ where Φ is a convenient function which …

Spectral entropy based neuronal network synchronization analysis based on microelectrode array measurements

Synchrony and asynchrony are essential aspects of the functioning of interconnected neuronal cells and networks. New information on neuronal synchronization can be expected to aid in understanding these systems. Synchronization provides insight in the functional connectivity and the spatial distribution of the information processing in the networks. Synchronization is generally studied with time domain analysis of neuronal events, or using direct frequency spectrum analysis, e.g., in specific frequency bands. However, these methods have their pitfalls. Thus, we have previously proposed a method to analyze temporal changes in the complexity of the frequency of signals originating from differ…

Corrigendum: Spectral Entropy Based Neuronal Network Synchronization Analysis Based on Microelectrode Array Measurements