0000000000152668

AUTHOR

N Khalid

showing 5 related works from this author

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

operativeMalepostoperative dischargePostoperative Complications0302 clinical medicineColostomyCRITERIAProspective StudiesBowel functionColectomyIMAGINEstomaintestinesProctectomyIleostomydigestive oral and skin physiologypatient dischargecolorectal surgery hospital discharge bowel functionRECOVERYMiddle Agedadult; colostomy; elective surgical procedures; female; follow-up studies; humans; ileostomy; ileus; male; middle aged; multivariate analysis; patient discharge; patient readmission; patient safety; postoperative complications; prospective studies; recovery of function; colectomy; proctectomyPatient DischargeColorectal surgeryileus - - discharge - bowel function - elective - colorectal surgeryElective Surgical Procedures030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologyPatient SafetyCohort studysafetyAdultmedicine.medical_specialtyIleusPatient Readmissiondefecation03 medical and health sciencesIleuspostoperative complicationsmedicineHospital dischargeHumanscolorectal surgery; postoperative discharge; IMAGINE; stomacolorectal resectionColorectal resectiondefecation postoperative complications colorectal surgery intestines patient discharge patient readmission safety surgical procedures operative colorectal resection ileusbusiness.industryRecovery of FunctionOdds ratiomedicine.diseasedigestive system diseasessurgical proceduresSurgeryMultivariate AnalysisDefecationcolorectal surgerySurgerybusinessFollow-Up Studies
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Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000-2018

2021

Exclusive breastfeeding (EBF)—giving infants only breast-milk for the first 6 months of life—is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and progress across low- and middle-income countries (LMICs) are required for planning policy and interventions. Here we present a geospatial analysis of EBF prevalence estimates from 2000 to 2018 across 94 LMICs mapped to policy-relevant administrative units (for example, districts), quantify subnational inequalities and their changes over time, and estimate probabilities of meeting the World Health …

RJ101Psychological interventionBreastfeedingSocial SciencesgeographyBehavioral Neuroscience0302 clinical medicineRA0421PrevalencePsychologypolicy making030212 general & internal medicinePolicy Makinghumansmedia_commonCHILD GROWTH FAILUREDeveloping world0303 health scienceseducation.field_of_studyPsychology BiologicalGeographyPsychology ExperimentalHealth Status DisparitieMultidisciplinary SciencesGeographyBreast Feedingbreast feedingScale (social sciences)Science & Technology - Other TopicsLife Sciences & BiomedicineHumanAFRICASocial PsychologyInequalityspatial analysismedia_common.quotation_subjectpublic policyPopulationprevalencePublic policyDeveloping countryExperimental and Cognitive PsychologyPublic PolicyLocal Burden of Disease Exclusive Breastfeeding CollaboratorsArticleDeveloping Countrie03 medical and health sciencesEnvironmental healthHumansNutrition disorderseducationDeveloping Countries030304 developmental biologySpatial AnalysisScience & TechnologyNeurosciencesHealth Status Disparitiesdeveloping countrieshealth status disparitiesRisk factorsNeurosciences & NeurologyBreast feedingNature Human Behaviour
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study…

2021

Background Documentation of patterns and long-term trends in mortality in young people, which reflect huge changes in demographic and social determinants of adolescent health, enables identification of global investment priorities for this age group. We aimed to analyse data on the number of deaths, years of life lost, and mortality rates by sex and age group in people aged 10–24 years in 204 countries and territories from 1950 to 2019 by use of estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods We report trends in estimated total numbers of deaths and mortality rate per 100 000 population in young people aged 10–24 years by age group (10–14 y…

MaleJoves -- MortalitatADOLESCENT HEALTHCHILDRENSocioeconomic FactorGlobal Burden of DiseaseRA0421Cause of DeathMedicineYoung adultChild11 Medical and Health SciencesCause of deatheducation.field_of_studyAdolescent; Age Distribution; Cause of Death; Child; Female; Global Burden of Disease; Humans; Male; Mortality; Sex Distribution; Socioeconomic Factors; Young AdultMortality ratePublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineArticlesHälsovetenskaperMIDDLE-INCOMEFemaleMENTAL-HEALTHAdolescent healthINTERVENTIONSHumanSUICIDEAdolescentTotal fertility ratePopulationAdolescent HealthAdolescents -- MortalitatYoung AdultAge DistributionGeneral & Internal MedicineHealth SciencesHumansQUALITY:Medicine [Science]Social determinants of healthINCOME COUNTRIESMortalitySex Distributioneducationbusiness.industryTRENDSFolkhälsovetenskap global hälsa socialmedicin och epidemiologiYears of potential life lostSocioeconomic FactorsINJURIESbusinessDemographyLancet
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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

2021

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Additionally, we provide subnational disparity analyses to provide a comprehensive overview of anemia prevalence inequalities within these countries and predict progress toward the World Health Organization’s Global Nutrition Target (WHO GNT) to reduce anemia by half by 2030. Our results …

Psychological interventionDiseasesResearch & Experimental MedicineGlobal HealthPrevalence11 Medical and Health Sciencesmedia_commonCHILD GROWTH FAILUREPublic Health Global Health Social Medicine and EpidemiologyAnemiaGeneral MedicineMiddle AgedanemiaPeer reviewIRON-DEFICIENCYNutritional StatuPREGNANCYMedicine Research & ExperimentalScale (social sciences)reproductive age/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingA990 Medicine and Dentistry not elsewhere classifiedFemalewomenLife Sciences & Biomedicinevulnerable populationsHumanAdultmedicine.medical_specialtyBiochemistry & Molecular BiologyInequalityAdolescentAnemiamedia_common.quotation_subjectMODELSImmunologyNutritional StatusReproductive ageLocal Burden of Disease Anaemia CollaboratorsGeneral Biochemistry Genetics and Molecular BiologyDeveloping CountrieYoung AdultSDG 3 - Good Health and Well-beingEnvironmental healthmedicineLife ScienceHumansDeveloping CountriesPovertyGlobal NutritionPregnancyWereldvoedingScience & Technologybusiness.industryPublic healthCell BiologyGLOBAL BURDENmedicine.diseaseFolkhälsovetenskap global hälsa socialmedicin och epidemiologiRisk factors1182 Biochemistry cell and molecular biology3111 Biomedicinebusiness
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