0000000000158285

AUTHOR

Davide Peddis

0000-0003-0810-8860

showing 2 related works from this author

Folate targeted coated SPIONs as efficient tool for MRI

2017

The development of more sensitive diagnostic tools allowing an early-stage and highly efficient medical imaging of tumors remains a challenge. Magnetic nanoparticles seem to be the contrast agents with the highest potential, if properly constructed. Therefore, in this study, hybrid magnetic nanoarchitectures were developed using a new amphiphilic inulin-based graft copolymer (INU-LAPEG-FA) as coating material for 10-nm spinel iron oxide (magnetite, Fe3O4) superparamagnetic nanoparticles (SPION). Folic acid (FA) covalently linked to the coating copolymer in order to be exposed onto the nanoparticle surface was chosen as the targeting agent because folate receptors are upregulated in many can…

magnetic resonance imaging (MRI)Materials sciencecancer targetingfolic acid (FA)NanoparticleNanotechnology02 engineering and technologyengineering.material010402 general chemistryDiagnostic tools01 natural sciencesCoatingsuperparamagnetic spinel iron oxide nanoparticles (SPIONs)AmphiphilemedicineGeneral Materials ScienceElectrical and Electronic Engineeringinulin copolymermedicine.diagnostic_testMagnetic resonance imaging021001 nanoscience & nanotechnologyCondensed Matter PhysicsAtomic and Molecular Physics and Optics0104 chemical sciencesMagnetic hyperthermiaFolic acidengineeringMagnetic nanoparticlesMaterials Science (all)0210 nano-technologyhuman activities
researchProduct

Manganese iron oxide superparamagnetic powder by mechanochemical processing. Nanoparticles functionalization and dispersion in a nanofluid

2012

Manganese ferrite nanoparticles were synthesized using a High-Energy Ball-Milling mechanochemical method. After 1 h of milling, the process produces a material consisting of single crystalline domain nanoparticles having a diameter of about 8 nm. Chemical properties of the synthesized powders allow an easy functionalization with citric acid. Both as-obtained and functionalized samples show superparamagnetic behaviour at room temperature, and the functionalized powder is stably dispersible in aqueous media at physiological pH. The average hydrodynamic diameter is equal to similar to 60 nm. Nanoparticles obtained by the reported High-Energy Ball-Milling method can be synthesized with high yie…

Materials scienceNanoparticlechemistry.chemical_elementBioengineeringNanotechnologyFerrite; Ferrofluid; Magnetic nanoparticles; Mechanochemical synthesis; Nanomedicine; Synthesis of nanofluidsManganeseNanofluidSynthesis of nanofluidsGeneral Materials ScienceFerriteGeneral ChemistryMagnetic nanoparticlesFerrite Mechanochemical synthesisFerrofluid NanomedicineSynthesis of nanofluidsCondensed Matter PhysicsAtomic and Molecular Physics and OpticsNanomedicinechemistryChemical engineeringFerrofluidModeling and SimulationMagnetic nanoparticlesSurface modificationNanomedicineFerrite (magnet)Magnetic nanoparticlesMechanochemical synthesisSuperparamagnetism
researchProduct