0000000000161271
AUTHOR
V. Lanza
Une méthode rapide et simple pour l'estimation de la position de la courbe de dissociation de l'oxyhémoglobine
The methods currently available for assessing the oxyhaemoglobin dissociation curve parameters are expensive, lengthy, require a large volume of blood, and the results obtained are modified by anaesthetic gases. The equipment required for the method described includes: a microtonometre, microcuvettes, 3 gas bottles containing different oxygen, carbon dioxide and nitrogen mixtures (4.5%, 5.6%, 89.9%; 3.5%, 5.6%, 90.9%; 2.5%, 5.6%, 91.9% respectively), a microxymetre, and a micropHmetre. The samples in the microcuvettes are incubated at 37 degrees C in a gas flow of 45 ml.min-1 from the bottles. SO2 is then read using the microxymetre. P50, i.e. PO2 at 50% saturation, is calculated, as well a…
An introduction to Open Source software licensing and use in anaesthesia department
EU member states are supporting the Open Source initiative suggesting the adoption of free software in government installation instead of commercial software. The latest national laws suggest adoption of Open Source solutions in educational structures as well, such as in schools and universities. It is clear that imprisoning knowledge with license fees does not allow any improvement nor any growth.
Correction of the unfavourable effects of vasopressin by nitroglycerin infusion
Nitroglycerin was administered with vasopressin to prevent adverse effects. Vasopressin 0.25U . 70 kg-1 min-1 was infused intravenously in four dogs for 40 minutes, when a venous infusion of nitroglycerin 1.2 micrograms . kg-1 . min-1 was added for 20 minutes. Nitroglycerin 1.2 micrograms . kg-1 . min-1 alone was infused intravenously in another four dogs for 40 minutes. The venous blood pressures (mesenteric and central) and arterial pressures (mesenteric and femoral), the electrocardiogram and arterio-venous difference were recorded. Nitroglycerin was shown to annul the unfavourable effects of vasopressin without altering its efficacy upon portal pressure.
La réponse neuro-endocrinienne à l'anesthésie par isoflurane
Resume Dans le contexte de la reaction endocrinienne et metabolique a l'anesthesie et a la chirurgie, les effets de l'isoflurane sur l'axe hypothalamohypophysocorticosurrenalien et le systeme hypothalamothyroidien ont ete etudies. L'ACTH, le cortisol, la TSH, la T3, la T4 et la prolactine ont ete doses chez 16 patients avant et au cours de l'intervention chirurgicale sous anesthesie avec isoflurane. Les resultats objectivent une augmentation significative des valeurs de la prolactine, du cortisol et de T4, permettant de conclure que l'isoflurane ne bloque pas l'augmentation du taux plasmatique de ces hormones au cours du stress chirurgical et se comporte donc a ce point de vue comme l'enflu…