0000000000163031

AUTHOR

Stefano Furlani

Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial.

BackgroundRespiratory complications are an important cause of postoperative morbidity. We aimed to investigate whether continuous positive airway pressure (CPAP) administered immediately after major abdominal surgery could prevent postoperative morbidity.MethodsPRISM was an open-label, randomised, phase 3 trial done at 70 hospitals across six countries. Patients aged 50 years or older who were undergoing elective major open abdominal surgery were randomly assigned (1:1) to receive CPAP within 4 h of the end of surgery or usual postoperative care. Patients were randomly assigned using a computer-generated minimisation algorithm with inbuilt concealment. The primary outcome was a composite of…

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Relative sea-level rise and potential submersion risk for 2100 on 16 coastal plains of the mediterranean sea

The coasts of the Mediterranean Sea are dynamic habitats in which human activities have been conducted for centuries and which feature micro-tidal environments with about 0.40 m of range. For this reason, human settlements are still concentrated along a narrow coastline strip, where any change in the sea level and coastal dynamics may impact anthropic activities. In the frame of the RITMARE and the Copernicus Projects, we analyzed light detection and ranging (LiDAR) and Copernicus Earth Observation data to provide estimates of potential marine submersion for 2100 for 16 small-sized coastal plains located in the Italian peninsula and four Mediterranean countries (France, Spain, Tunisia, Cypr…

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Holocene sea level change in Malta

A multidisciplinary approach has been applied to study sea level changes along the coast of Malta using data collected from underwater archaeological remains. The elevation of archaeological markers have been compared with predicted sea level curves providing new bodies of evidence that outline the vertical tectonic behaviour of this region, allowing estimation of the relative sea level changes that occurred in this area of the Mediterranean since the Bronze Age. During the Roman Age, sea level was at −1.36 ± 0.1 m, while in the Midde Age it was at −0.56 ± 0.2 m, in agreement with previous estimations for the Mediterranean region. Data indicate that Malta was tectonically stable during the …

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Preservation of modern and mis 5.5 erosional landforms and biological structures as sea level markers: A matter of luck?

The Mediterranean Basin is characterized by a significant variability in tectonic behaviour, ranging from subsidence to uplifting. However, those coastal areas considered to be tectonically stable show coastal landforms at elevations consistent with eustatic and isostatic sea level change models. In particular, geomorphological indicators—such as tidal notches or shore platforms—are often used to define the tectonic stability of the Mediterranean coasts. We present the results of swim surveys in nine rocky coastal sectors in the central Mediterranean Sea using the Geoswim approach. The entire route was covered in 22 days for a total distance of 158.5 km. All surveyed sites are considered to…

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Tidal notches, coastal landforms and relative sea-level changes during the Late Quaternary at Ustica Island (Tyrrhenian Sea, Italy)

In this paper we present and discuss data concerning the morphostructural evolution at Ustica Island (Tyrrhenian Sea, Italy) during Late Quaternary. New insights on the relative sea-level changes of Ustica are coming from data collected during a geomorphological field survey around the island, together with the bathymetric analysis of the surrounding seabed and 14C datings on samples of speleothems, flowstones and marine shells found inside three selected sea caves. The survey was mainly accomplished on June 2015 through the first complete snorkel investigation off the about 18 km-long volcanic coast of the island, which allowed to precisely define location, relationship and morphometric fe…

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Palaeogeographical evolution of the Egadi Islands (western Sicily, Italy). Implications for late Pleistocene and early Holocene sea crossings by humans and other mammals in the western Mediterranean

Abstract The continental shelf morphology offshore of western Sicily suggests that during the Last Glacial Maximum (LGM, 20 ka cal BP), two of the Egadi Islands, Favignana and Levanzo, were connected to Sicily by a wide emerged plain, while Marettimo was only separated from the other islands by a narrow channel. We studied the relative sea-level variation from the LGM until today, focussing on two important time slices: the Mesolithic (9.5–13 ka cal BP) and the Neolithic (6.5–7.5 ka cal BP). In this research, we discuss a sea-level rise model by means of geomorphological, archaeological and geophysical observations and new radiocarbon dating of marine and terrestrial fossil fauna. The resul…

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Reply to comment by C. Morhange, C. Flaux, P.A. Pirazzoli, M.B. Carre on “Holocene Sea level Change in Malta”

The pits of Birzebbugia are located near the present-day mean sea level, and some are partially submerged. They were dated using pottery discovered in an archaeological site close to the coast, dated to the Bronze Age (Zammit, 1928; Abela, 1999). As they have been interpreted as sites for the retting of flax, during their utilization they should have remained dry and the sea could not submerge them. This is the reason why these structures are not directly related to the sea level, as suggested by Biolchi et al. (2011), so they represent an upper limit.

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Submerged speleothems and sea level reconstructions: a global overview and new results from the Mediterranean Sea

This study presents a global overview of the submerged speleothems used to reconstruct paleo sea levels and reports new results from two stalactites collected in the Mediterranean Sea. Coastal cave deposits significantly contributed to the understanding of global and regional sea-level variations during the Middle and Late Quaternary. The studied speleothems cover the last 1.4 Myr and focused mainly on Marine Isotope Stages (MIS) 1, 2, 3, 5.1, 5.3, 5.5, 7.1, 7.2, 7.3 and 7.5. The results indicate that submerged speleothems represent extraordinary archives that can provide detailed information on former sea-level changes. The two stalactites collected in the central Mediterranean Sea, at Fa…

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