0000000000164197
AUTHOR
Gabriella Amodeo
Persistence of High Plasma Elastase Level in Young Subjects With Acute Myocardial Infarction
Esercizio fisico ed emoreologia
Polymorphonuclear leukocyte membrane fluidity and cytosolic Ca2+ concentration in subjects with vascular atherosclerotic disease subdivided according to the extent.
An abnormal activation state of polymorphonuclear leukocytes (PMN) plays a key role in organ injury induced by vascular atherosclerotic disease (VAD) and diabetes mellitus (DM). PMN membrane fluidity and cytosolic Ca2+ content can be considered markers of PMN activation. In this research we evaluated the PMN membrane fluidity and cytosolic Ca2+ content in VAD subjects with and without type 2 DM and examined the association between these parameters and the mono- or polyvascular localization. We enrolled 155 VAD subjects, including 92 non-diabetic (group A: mean age 63.6 +/- 9.2 years) and 63 diabetic patients (group B: mean age 65.4 +/- 7.8 years). Among group A 63 patients had monovascular …
Correlation between markers of oxidative status and plasma elastase in juvenile myocardial infarction.
Hemorheological pattern in different groups of athletes submitted to cardio-pulmonary exercise test
Pattern emoreologico in diversi gruppi di atleti sottoposti a test da sforzo cardiopolmonare.
Acute ischemic stroke: behaviour of granulocyte membrane fluidity and cytosolic Ca2+ content at baseline and after in vitro activation
Polymorphonuclear leukocyte: rheology, metabolism and integrin pattern in vascular atherosclerotic disease and in type 2 diabetes mellitus
Leukocytes, and in particular polymorphonuclear cells (PMN), play a role in the organ injury that characterizes the progression of vascular atherosclerotic disease (VAD) and diabetes mellitus (DM). We enrolled subjects with VAD, subjects with type 2 DM (DM2) and subjects with VAD and DM2. We evaluated the initial relative flow rate (IRFR) of PMN, using the St. George Filtrometer, the PMN membrane fluidity, labelling intact PMN cells with the fluorescent probe 1.4-(trimethylamino)-phenyl-4-phenylhexatriene (TMA-DPH), the PMN cytosolic Ca2+ content marking the cells with the fluorescent probe Fura 2-AM and the PMN integrin profile using the flow cytofluorimetry. All these evaluations were eff…
Cardiopatia ischemica cronica: pattern integrinico dei leucociti polimorfonucleati dopo attivazione in vitro e durante test ergometrico
Emoreologia negli atleti
Valutazione dell’assetto emoreologico in condizioni basali e dopo prova da sforzo cardio-polmonare in atleti che praticano attività sportiva con diverso impegno energetico
Deformabilita' eritrocitaria, metaboliti stabili dell'NO e perossidazione lipidica in atleti non professionisti
Polymorphonuclear leukocyte integrin expression in subjects with type 1 and 2 diabetes mellitus
Behaviour of the oxidative status in athletes before and after a cardio-pulmonary test
Relationship between elastase and total antioxidant status in young subjects with recent myocardial infarction
In a group of young subjects with acute myocardial infarction (AMI) (68 men and 7 women; mean age 39.6 ± 5.7 years) we examined the plasma concentration of elastase, the thiobarbituric acid-reactive substances (TBARS) and the total antioxidant status (TAS) at the initial stage of AMI. In this group we found an increase of elastase (p <0.001) and TBARS (p < 0.001) and a decrease of TAS (p < 0.001). A statistical correlation was observed in the whole group of AMI patients between plasma elastase and TAS (p < 0.01) and this correlation was more statistically significant in patients with more risk factors and not in those with more involved vessels.
Emoreologia, stress ossidativo ed attività agonistica.
Erythrocyte deformability and nitric oxide metabolites in athletes before and after a cardio-pulmonary test
Stress ossidativo in un gruppo di atleti sottoposti a test da sforzo cardiopolmonare.
Erythrocyte deformability and nitric oxide metabolites in athletes before and after a cardiopulmonary test.
OBJECTIVE: To evaluate erythrocyte deformability, nitric oxide metabolites, and their modifications induced by exercise in athletes who practised different sports. DESIGN: This evaluation was effected before and after cardiopulmonary test, using a cycloergometer. SETTING: The study was performed in the Department of Internal Medicine, Cardiovascular and Renal Diseases of the University of Palermo. PARTICIPANTS: We enrolled 62 male athletes who practised endurance (n = 23), mixed (n = 20), and power (n = 19) sports and 20 sedentary male subjects as controls. ASSESSMENT OF RISK FACTORS: No subject had diabetes or hypertension or dyslipidemia. Five control subjects and 14 athletes were smokers…
Relationship between lipid peroxidation and total antioxidant status in juvenile myocardial infarction.
Lipid peroxidation and total antioxidant status in unprofessional athletes before and after a cardiopulmonary test.
We examined lipid peroxidation, expressed as thiobarbituric acid-reactive substances (TBARS) and total antioxidant status (TAS) before and after a cardiopulmonary test, in 20 sedentary controls and in 62 unprofessional male athletes subdivided into 3 subgroups. The first included subjects who practised endurance sports (14 cyclists and 9 endurance swimmers), the second subjects who practised mixed sports (6 basket players, 6 judoists, 8 water polo players) and the third group subjects who practised power sports (3 sprint runners, 4 weightlifters, 12 sprint swimmers). In the whole group of athletes an increase in TBARS and a decrease in TAS were present at baseline. Subdividing the whole gro…