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RESEARCH PRODUCT

Relationship between elastase and total antioxidant status in young subjects with recent myocardial infarction

Maria MontanaBaldassare CaninoGregorio CaimiGabriella AmodeoRosalia Lo PrestiDaniela LucidoAdele RomanoAnna Catania

subject

AdultMaletotal antioxidant statusmedicine.medical_specialtyanimal structuresPhysiologyMyocardial InfarctionThiobarbituric Acid Reactive SubstancesGastroenterologyAntioxidantsPhysiology (medical)Internal medicineTBARSHumansMedicineIn patientMyocardial infarctionPancreatic Elastasebusiness.industryElastaseCase-control studyHematologyMiddle Agedmedicine.diseaseJuvenile myocardial infarctionplasma elastaseOxidative StressAntioxidant capacityCase-Control StudiesImmunologyFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersStatistical correlationRecent myocardial infarction

description

In a group of young subjects with acute myocardial infarction (AMI) (68 men and 7 women; mean age 39.6 ± 5.7 years) we examined the plasma concentration of elastase, the thiobarbituric acid-reactive substances (TBARS) and the total antioxidant status (TAS) at the initial stage of AMI. In this group we found an increase of elastase (p <0.001) and TBARS (p < 0.001) and a decrease of TAS (p < 0.001). A statistical correlation was observed in the whole group of AMI patients between plasma elastase and TAS (p < 0.01) and this correlation was more statistically significant in patients with more risk factors and not in those with more involved vessels.

yearjournalcountryeditionlanguage
2008-09-16Clinical Hemorheology and Microcirculation
https://doi.org/10.3233/ch-2008-1060